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| 1 | Role of insulin resistance in uric acid nephrolithiasis显示文摘Metabolic syndrome has been implicated in the pathogenesis of uric acid stones.Although not completely understood,its role is supported by many studies demonstrating increased prevalence of uric acid stones in patients with metabolic syndrome and in particular insulin resistance,a major component of metabolic syndrome.This review presents epidemiologic studies demonstrating the association between metabolic syndrome and nephrolithiasis in general as well as the relationship between insulin resistance and uric acid stone formation,in particular.We also review studies that explore the pathophysiologic relationship between insulin resistance and uric acid nephrolithiasis. | Hanhan Li Dane E Klett Raymond Littleton Jack S Elder Jesse D Sammon | 2014 | World Journal of Nephrology2014，3，4： | 6 |
| 2 | Automated defect analysis in electron microscopic images显示文摘Electron microscopy and defect analysis are a cornerstone of materials science,as they offer detailed insights on the microstructure and performance of a wide range of materials and material systems.Building a robust and flexible platform for automated defect recognition and classification in electron microscopy will result in the completion of analysis orders of magnitude faster after images are recorded,or even online during image acquisition.Automated analysis has the potential to be significantly more efficient,accurate,and repeatable than human analysis,and it can scale with the increasingly important methods of automated data generation.Herein,an automated recognition tool is developed based on a computer vison–based approach;it sequentially applies a cascade object detector,convolutional neural network,and local image analysis methods.We demonstrate that the automated tool performs as well as or better than manual human detection in terms of recall and precision and achieves quantitative image/defect analysis metrics close to the human average.The proposed approach works for images of varying contrast,brightness,and magnification.These promising results suggest that this and similar approaches are worth exploring for detecting multiple defect types and have the potential to locate,classify,and measure quantitative features for a range of defect types,materials,and electron microscopic techniques. | Wei Li Kevin G.Field Dane Morgan | 2018 | npj Computational Materials2018，，1： | 5 |
| 3 | Intercomparison of GPS radiosonde soundings during the eastern tropical Indian Ocean experiment显示文摘Temperature and relative humidity profiles derived from two China-made global positioning system(GPS)radiosondes(GPS-TK and CF-06-A)during the east tropical Indian Ocean(ETIO)experiment were compared with Vaisala RS92-SGP to assess the performances of China-made radiosondes over the tropical ocean.The results show that there have relative large biases in temperature observations between the GPSTK and the RS92-SGP in the low troposphere,with a warm bias of greater than 2 K in the day and a cooling bias of 0.6 K at night.The temperature differences of the CF-06-A were small in the troposphere both in daytime and nighttime,and became large peak-to-peak fluctuations in the stratosphere.The intercomparison of the relative humidity showed that the CF-06-A had large random errors due to the limitation of sensors and the lack of correction scheme,and the GPS-TK had large systematic biases in the low troposphere which might be related to the temperature impact.GPS height measurements are clearly suitable for China-made radiosonde systems operation.At night,the CF-06-A and the GPS-TK could provide virtual potential temperature and atmospheric boundary layer height measurements of suitable quality for both weather and climate research.As a result of the intercomparison experiment,major errors in the Chinamade radiosonde systems were well indentified and subsequently rectified to ensure improving accuracy for historical and future radiosondes. | XIE Qiang HUANG Ke WANG Dongxiao YANG Lei CHEN Ju WU Zewen LI Daning LIANG Zhiyan | 2014 | Acta Oceanologica Sinica2014，33，1： | 4 |
| 4 | Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells显示文摘Background: The objective of this study was to study how changing the ratio of Lys to Thr, Lys to His, and Lys to Val affects the expression of lipogenic genes and micro RNA(mi RNA) in bovine mammary epithelial cells.Results: Triplicate cultures with the respective 'optimal' amino acid(AA) ratio(OPAA = Lys:Met 2.9:1; Thr:Phe 1.05:1;Lys:Thr 1.8:1; Lys:His 2.38:1; Lys:Val 1.23:1) plus rapamycin(OPAARMC; positive control), OPAA, Lys:Thr 2.1:1(LT2.1),Lys:Thr 1.3:1(LT1.3), Lys:His 3.05:1(LH3.0), or Lys:Val 1.62:1(LV1.6) were incubated in lactogenic medium for 12 h.The expression of 15 lipogenic genes and 7 mi RNA were evaluated. Responses to LT2.1, LT1.3, LH3.0, and LV1.6relative to the control(OPAARMC) included up-regulated expression of ACSS2, FABP3, ACACA, FASN, SCD, LPIN1,INSIG1, SREBF1, PPARD, and NR1H3(commonly known as LXR-α). Furthermore, LV1.6 up-regulated expression of ACSL1, DGAT1, and RXRA and down-regulated PPARG expression. Although no effect of OPAA on expression of PPARG was observed, compared with the control, OPAA up-regulated expression of the PPAR targets ACSS2, FABP3,ACACA, FASN, SCD, LPIN1, INSIG1, and SREBF1. Compared with the control, the expression of the anti-lipogenic MIR27 AB was down-regulated by OPAA, LT2.1, LT1.3 and LH3.0. In contrast, compared with the control, the expression of the pro-lipogenic MIR21 was up-regulated by LT2.1, LT1.3, LH3.0, and LV1.6.Conclusions: The observed up-regulation of lipogenic gene networks and the changes in expression of key mi RNA involved in the control of lipogenic balance are indicative of a potentially important role of EAA ratios and m TOR signaling in the regulation of milk fat synthesis. | Shanshan Li Afshin Hosseini Marina Danes Carolina Jacometo Jianxin Liu Juan J.Loor | 2016 | Journal of Animal Science and Biotechnology2016，7，4： | 3 |
| 5 | Improved characteristics and protective efficacy in an animal model of E. coli -derived recombinant double-layered rotavirus virus-like particles显示文摘 | Tingdong Li Haijun Lin Yue Zhang Min Li Daning Wang Yaojian Che Yinbin Zhu Shaowei Li Jun Zhang Shengxiang Ge Qinjian Zhao Ningshao Xia | 2014 | Vaccine2014，，： | 2 |
| 6 | Systemic risk management and investment analysis with financial network analytics:research opportunities and challenges显示文摘Recent economic crises like the 2008 financial tsunami has demonstrated a critical need for better understanding of the topologies and various economic,social,and technical mechanisms of the increasingly interconnected global financial system.Such a system largely relies on the interconnectedness of various financial entities such as banks,firms,and investors through complex financial relationships such as interbank payment networks,investment relations,or supply chains.A network-based perspective or approach is needed to study various financial networks in order to improve or extend financial theories,as well as develop business applications.Moreover,with the advance of big data related technologies,and the availability of huge amounts of financial and economic network data,advanced computing technologies and data analytics that can comprehend such big data are also needed.We referred this approach as financial network analytics.We suggest that it will enable stakeholders better understand the network dynamics within the interconnected global financial system and help designing financial policies such as managing and monitoring banking systemic risk,as well as developing intelligent business applications like banking advisory systems.In this paper,we review the existing research about financial network analytics and then discuss its main research challenges from the economic,social,and technological perspectives. | Daning Hu Gerhard Schwabe Xiao Li | 2015 | Financial Innovation2015，1，1： | 2 |
| 7 | Computer Simulation of Molecular Diffusion in Amorphous Polymers显示文摘 | LI Tong-lei DANE O K KINAM P | 1997 | Journal of Controlled Release1997，48，： | 1 |
| 8 | Computer simulation of molecular diffusion in amorphous polymers显示文摘 | Tonglei Li Dane O. Kildsig Kinam Park | 1997 | Journal of Controlled Release1997，，1： | 1 |
| 9 | Computer simulation of molecular diffusion in amorphous polymers 显示文摘 | Li Tonglei Dane O Kildsig Kinam Park | 1997 | Journal of Controlled Release1997，48，： | 1 |
| 10 | Tranexamic acid can treat ultraviolet radiation-induced pigmentation in guinea pigs 显示文摘 | Daning L1 Yu SHI Meiyun LI | 2010 | Eur J Dermatol2010，20，3： | 1 |
| 11 | Exploiting Multi-scale Support Vector Regression for Image Compression显示文摘 | Li Bin Zheng Daning Sun Lifeng | | 0，，16： | 1 |
| 12 | Calibration after bootstrap for accurate uncertainty quantification in regression models显示文摘Obtaining accurate estimates of machine learning model uncertainties on newly predicted data is essential for understanding the accuracy of the model and whether its predictions can be trusted.A common approach to such uncertainty quantification is to estimate the variance from an ensemble of models,which are often generated by the generally applicable bootstrap method.In this work,we demonstrate that the direct bootstrap ensemble standard deviation is not an accurate estimate of uncertainty but that it can be simply calibrated to dramatically improve its accuracy.We demonstrate the effectiveness of this calibration method for both synthetic data and numerous physical datasets from the field of Materials Science and Engineering.The approach is motivated by applications in physical and biological science but is quite general and should be applicable for uncertainty quantification in a wide range of machine learning regression models. | Glenn Palmer Siqi Du Alexander Politowicz Joshua Paul Emory Xiyu Yang Anupraas Gautam Grishma Gupta Zhelong Li Ryan Jacobs Dane Morgan | 2022 | npj Computational Materials2022，，1： | 0 |
| 13 | System Identification Modeling and Unstable Behavior of the Dynamics of Flows within the Tip Region of an Axial Compressor Blade Passage显示文摘In recent years, the correlation coefficient of pressure data from the same blade passage in an axial compressor unit has been used to characterize the state of flow in the blade passage. In addition, the correlation coefficient has been successfully used as an indicator for active control action using air injection. In this work, the correlation coefficient approach is extended to incorporate system identification algorithms in order to extract a mathematical model of the dynamics of the flows within a blade passage. The dynamics analyzed in this research focus on the flow streams and pressure along the rotor blades as well as on the unsteady tip leakage flow from the rotor tip gaps. The system identification results are used to construct a root locus plot for different flow coefficients, starting far away from stall to near stall conditions. As the compressor moves closer to stall, the poles of the identified models move towards the imaginary axis of the complex plane, indicating an impending instability. System frequency data is captured using the proposed correlation based system identification approach. Additionally, an oscillatory tip leakage flow is observed at a flow coefficient away from stall and how this oscillation changes as the compressor approaches stall is an interesting result of this research. Comparative research is analyzed to determine why the oscillatory flow behavior occurs at a specific sensor location within the tip region of the rotor blade. | STERBENTZ Dane M. PRASAI Sujan HOFLE Mary M. WALTERS Thomas LIN Feng LI Ji-chao BOSWORTH Ken SCHOEN Marco P. | 2016 | Journal of Thermal Science2016，25，2： | 0 |
| 14 | 人乳头瘤病毒衣壳蛋白C末端结构臂具有免疫原性并参与病毒-宿主细胞的相互作用显示文摘宫颈癌是全球女性第二大常见恶性肿瘤,人乳头瘤病毒(HPV)是导致女性宫颈癌发生的主要原因。HPV型别众多,主要的高危型型别种类多达15种,且型别间免疫血清交叉保护能力极低,目前国际上已上市的预防性多价HPV疫苗均不能为接种者提供完全保护。 | Zhihai Li Xiaodong Yan Hai Yu Daning Wang Shuo Song Yunbing Li Maozhou He Qiyang Hong Qingbing Zheng Qinjian Zhao Ying Gu Jun Zhang Mandy E.W.Janssen Giovanni Cardone Norman H.Olson Timothy S.Baker 李少伟 Ningshao Xia | 2017 | 科学新闻2017，19，4： | 0 |
| 15 | Nonparametric multivariate analysis of variance for affecting factors on the extent of forest fire damage in Jilin Province, China显示文摘Forest fires are influenced by several factors,including forest location,species type,age and density,date of fire occurrence,temperatures,and wind speeds,among others.This study investigates the quantitative effects of these factors on the degree of forest fire disaster using nonparametric statistical methods to provide a theoretical basis and data support for forest fire management.Data on forest fire damage from 1969 to 2013 was analyzed.The results indicate that different forest locations and types,fire occurrence dates,temperatures,and wind speeds were statistically significant.The eastern regions of the study area experienced the highest fire occurrence,accounting for 85.0%of the total number of fires as well as the largest average forested area burned.April,May,and October had more frequent fires than other months,accounting for 78.9%,while September had the most extensive forested area burned(63.08 ha)and burnt area(106.34 ha).Hardwood mixed forest and oak forest had more frequent fires,accounting for 31.9%and 26.0%,respectively.Hardwood-conifer mixed forest had the most forested area burned(50.18 ha)and burnt area(65.09 ha).Temperatures,wind speeds,and their interaction had significant impacts on forested area burned and area burnt. | Jing Li Yanlong Shan Sainan Yin Mingxia Wang Long Sun Daning Wang | 2019 | Journal of Forestry Research2019，30，6： | 0 |
| 16 | Influence of ^(14)N^(7+) Ion Penetration and Implantation on Chromosomal Aberrations in Root Tip Cells显示文摘Influence of ^(14)N^(7+) Ion Penetration and Implantation on Chromosomal Aberrations in Root Tip CellsInfluenceof^(14)N^(7+)Ion... | Li Wenjian Wei Zengquan Xie Hongmei Li Qiang Dane Bingrong Han Guangwu | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 17 | A portable,auxiliary photovoltaic power system for electric vehicles based on a foldable scissors mechanism显示文摘In recent years,countries worldwide have actively advocated electric vehicles for environmental protection.How-ever,restrictions on the driving range and charging have hampered the promotion of electric vehicles.This study proposes a portable,auxiliary photovoltaic power system based on a foldable scissors mechanism for electric vehicles.The system includes a photovoltaic power generation module and an electricity transfer module.The photovoltaic power generation module built based on a foldable scissors mechanism is five times smaller than in its unfolded state,improving its portability in its folded state.The electricity transfer module transfers electricity into the cabin via wireless power transfer units and stores electricity in supercapacitors.Solar simulation exper-iments were conducted to evaluate the system’s performance:maximum output power of 1.736 W is measured when the load is 5Ω,while maximum wireless power transfer efficiency is up to 57.7% with 10Ω load.An elec-tric vehicle in Chengdu city was simulated for a case study.The results show that the annual output of a single photovoltaic power system can drive the MINIEV for 423.625 km,indicating that the proposed system would be able to supply power for electric vehicles as an auxiliary power supply system. | Zhou Jin Dongyang Li Daning Hao Zutao Zhang Liang Guo Xiaoping Wu Yanping Yuan | 2024 | Energy and Built Environment2024，5，1： | 0 |
| 18 | Effective fabrication of porous Au-Ag alloy nanorods for in situ Raman monitoring catalytic oxidation and reduction reactions显示文摘Porous metal nanostructures exhibit excellent catalytic properties due to their high surface-to-volume ratios and abundant catalytic active sites. However, it is still challenging to control nanopores density and structural features in a facile route and the preparation of porous alloy nanorods for catalytic application has not been well explored. In this work, we demonstrate a synthetic strategy to fabricate highly porous Au–Ag alloy nanorods(P-Au Ag NRs) by critically dealloying Ag atoms from homogeneous solid Au–Ag alloy nanorods(Au Ag NRs). Combining the merits of the tunable plasmonic properties of noble metal nanorods, excellent stabilities of alloys, and superior catalytic activities of porous structures, we use the P-Au Ag NRs as a Raman probe for the in situ monitoring of the catalytic oxidation of 3,3',5,5' tetramethylbenzidine(TMB) and reduction of 4-nitrothiophenol(4-NTP). We also compare their compositiondependent catalytic activities. The results show that P-Au Ag NRs possess superior chemical stability and higher catalytic activity than those of core-shell structures due to synergistic structural and chemical mechanisms. This strategy provides a predictive design approach for the next-generation alloy catalysts with high-performance. | Shanlin Ke Caixia Kan Xingzhong Zhu Changshun Wang Weijian Gao Zhaosheng Li Xiaoguang Zhu Daning Shi | 2021 | Journal of Materials Science & Technology2021，，32： | 0 |
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