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| 1 | Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer显示文摘AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality. | Mohamad A Mouchli Lidia Ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman | 2018 | World Journal of Gastroenterology2018，24，8： | 5 |
| 2 | Liver and colon DNA oxidative damage and gene expression profiles of rats fed Arabidopsis thaliana mutant seeds containing contrasted flavonoids 显示文摘 | Cristina L Lisa G Vanessa P | 2008 | Food and Chemical Toxicology2008，46，： | 1 |
| 3 | Stabilization of alumina with Poiyelectrolyte and Comb Copolymer in Solvent Mixtures of Water and alcohols显示文摘 | Ola L Lisa P Ells C | 2009 | Journal of the European Ceramic Society2009，29，： | 1 |
| 4 | Riparian woody plant diversity and forest structure along an urban-rural gradient显示文摘 | Michele L B Lisa J S Shufen P | 2005 | Urban E- cosystems2005，8，： | 1 |
| 5 | Clearance of hepatitis B eantigen in patients with chronic hepatitis B and genotypes A,B,C,D and F显示文摘 | Stephen E L Josephine P S Lisa R B | 2007 | Gastroenterology2007，133，5： | 1 |
| 6 | Antigen-driven murine CD4+ T lymphocyte proliferation and interleukin-2 production are diminished by dietary (n-3) polyunsaturated fatty acids 显示文摘 | Lisa J P Kevin L F | 2002 | J Nutr2002，32，： | 1 |
| 7 | Product toxicity and cometa- bolic competitive inhibition modeling of chloroform and trichloroethylene transformation by methanotrophic resting cells 显示文摘 | LISA A C MCCARTY P L | 1991 | Appl Environ Microbiol1991，57，4： | 1 |
| 8 | Specific Patterns of Gene Methylation in Natural killer cell lymphomas : P73 Is Consisitently Involved显示文摘 | LISA L P S JOHN K KITFAI W | 2002 | Am J Pathol2002，160，6： | 1 |
| 9 | Methane combustion over the a-alumina supported Pd catalyst: activity of the mixed Pd/PdO state显示文摘 | MAXIM L LISA P | 1998 | Applied Catalysis A1998，173，1： | 1 |
| 10 | Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat 显示文摘 | Angela C Sveva B Michela P Saverio S Andrea C Lisa G Jenny T Martina P Elisabetta L Gino G Igor V Emanuele C Annalisa A Laura I Giovanni F Z Anthony A Paolo D C and Saverio S | 2007 | Journal of Molecular and Cellular Cardiology2007，42，4： | 1 |
| 11 | Peanuts, peanut oil, and fat free peanut flour reduced cardiovascular disease risk factors and the development of atherosclerosis in syrian golden hamsters 显示文摘 | Amanda M Stephens Lisa L Dean Jack P Davis Jason A Osborne Timothy H Sanders | 2010 | Journal of Food Science2010，75，4： | 1 |
| 12 | In vitro metabolism of modazolam,triazolam,Nifedipine,and testosterone by human liver microsomes and recombinant cytochrome CPY:roles of CYP3A4 and CYP3A5显示文摘 | Kiran C P Lisa L Von M | 2003 | DMD2003，，31： | 1 |
| 13 | Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore显示文摘 | Scorrano L Petronilli V Di Lisa F Bernardi P | 1999 | J Biol Chem1999，274，22： | 1 |
| 14 | Identification of PVYNTN in potato tubers with necrotic ringspot in Piedmont 显示文摘 | Roggero P Del lvalle G Lisa V Weidemann H L | 1998 | Informatore Fitopatologico1998，48，3： | 1 |
| 15 | The plaintiff's attorney in the liability insur- ance claims settlement process: a game theoretic ap- proach显示文摘 | LISA L P | 1998 | Journal of Insurance Issues1998，21，2： | 1 |
| 16 | Viperin restricts chikungunya virus replication and pathology显示文摘 | Terk Shin Teng Suan Sin Foo Diane Simamarta Fok Moon Lum Teck Hui Teo Aleksei Lulla Nicholas K W Yeo Esther G L Koh Angela Chow Yee Sin Leo Andres Merits Keh Chuang Chin Lisa F P Ng | 2012 | J Cin Invest2012，122，12： | 1 |
| 17 | The effect of exper imental presentation of thin media images on body satisfaction: A meta-analytic review 显示文摘 | LISA M G MICHAEL P L SARAH K M | 2002 | Int J Eating Disorders2002，31，1： | 1 |
| 18 | Shortening Osteotomy and Compression Plating for Atrophic Humeral Nonunions: Surgical Technique显示文摘 | Michael L Brennan Lisa A Taitsman David P Barei Eric Puttler Sean E Nork | 2008 | Journal of Orthopaedic Trauma2008，，9： | 1 |
| 19 | Binding of to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice 显示文摘 | Harrington P R Lisa L norwalk virus-like particles Boyd Y | 2002 | J Virol2002，76，12： | 1 |
| 20 | Antigen-driven murine CD4^+ T lymphocyte proliferation and interleukin-2 production are diminished by dietary (n-3 ) polyunsaturated fatty acids 显示文摘 | Lisa J P Kevin L F | 2002 | J Nutr2002，32，： | 1 |
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