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| 1 | More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus显示文摘Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted. | Santosh K Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala Kamala Andrzej Ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius | 2019 | General Psychiatry2019，32，4： | 11 |
| 2 | Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial显示文摘 | D. Russell-Jones A. Vaag O. Schmitz B. K. Sethi N. Lalic S. Antic M. Zdravkovic G. M. Ravn R. Simó | 2009 | Diabetologia2009，，10： | 2 |
| 3 | Deletion and duplication screening in the DMD gene using MLPA显示文摘 | Lalic T Vossen RH Coffa J e al | 2005 | Eur J Hum Genet2005，13，： | 1 |
| 4 | Chromosome aberrations in peripheral bloodlymphocytes in subjects occupationally exposed to ionizing radiation orchemical clastogens显示文摘 | Lalic H Radosevic SB | 2002 | Folia Biol Praha2002，48，3： | 1 |
| 5 | Complex small supernumerary marker chromosomes-an update显示文摘 | Thomas Liehr Sanja Cirkovic Tanja Lalic | 2013 | Molecular Cytogenetics2013，6，： | 1 |
| 6 | Electroluminescence of single silicon nanocrystals 显示文摘 | Valenta J Lalic N Linnros J | 2004 | Appl Phys Lett2004，84，9： | 1 |
| 7 | Oxidized LDL and lipids as risk factor for ischemic heart disease in type 2 diabetes显示文摘 | Zamaklar M Lalic K Rajkovic N | 2005 | Vojnosanit Pregl2005，62，7： | 1 |
| 8 | Effect of various enamel etching on shear bond strength in orthodontics显示文摘 | Aleksic E Lalic M Perisic S | 2013 | Healthmed2013，，7： | 1 |
| 9 | Altered daytime fluctuation pattern of plasminogen activator inhibitor 1 in type 2 diabetes patients with coronary artery disease:A strong association with persistently elevated plasma insulin,increased insulin resistance,and abdominal obesity显示文摘 | Lalic K Jotic A Rajkovic N | 2015 | Int J Endocrinol2015，2015，39： | 1 |
| 10 | Relationship between obesity, adipoeytokines and inflammatory markers in type 2 diabetes : relevance for cardiovaseular risk prevention 显示文摘 | Rajkovic N Zamaklar M Lalic K | 2014 | Int J Environ Res Public Health2014，11，4： | 1 |
| 11 | Acute effects of ghrelin on insulin secretion and glucose disposal rate in gastrectomized patients显示文摘 | Damjanovic SS Lalic NM Pesko PM | 2006 | J Clin Endocrinol Metab2006，91，7： | 1 |
| 12 | Deletion and duplication screening in the DMD gene using MLPA 显示文摘 | Lalic T Vossen RH Coffa J | 2005 | Eur J Hum Genet2005，13，11： | 1 |
| 13 | The prevalence of hypertension and microalbuminuria in diabetes mellitus type l and type 2显示文摘 | Vasovic O Zamaklar M Lalic K | 2005 | Srpski Arhiv Za Celokupno Lekarstvo2005，133，56： | 1 |
| 14 | Urinary prostate-specific antigen:predictor of benign prostatic hyperplasia progres-sion? 显示文摘 | PEJCIC T P TULIC CDZ LALIC N V | 2013 | Can J Urol2013，20，2： | 1 |
| 15 | Hypertension in obese type 2 diabetes patients is associated with increases in insulin resistance and IL-6 cytokine levels: potential targets for an efficient preventive intervention 显示文摘 | Lukic L Lalic NM Rajkovic N | 2014 | Int J Environ Res Public Health2014，11，4： | 1 |
| 16 | Analysis of the stretched exponential photoluminescence decay from nano- meter-sized silicon crystals in SiO2 显示文摘 | LINNROS J LALIC N GALECKAS A | 1999 | J Appl Phys1999，86，11： | 1 |
| 17 | A porous silicon light-emitting diode with a high quantum efficiency during pulsed operation 显示文摘 | LALIC N LINNROS J | 1996 | Thin Solid Films1996，276，1： | 1 |
| 18 | The prevalence of hyper- tension and microalbuminuria in diabetes mellitus type 1 and type 2显示文摘 | Vasovic O Zamaklar M Lalic K | 2005 | Srp Arh Celok Lek2005，133，56： | 1 |
| 19 | Glucose homeostasis in Huntington disease: abnormalities in insulin sensitivity and early-phase insulin secretion 显示文摘 | Lalic NM Marie J Svetel M | 2008 | Arch Neurol2008，65，4： | 1 |
| 20 | Relationship between Obesity, Adipocytokines and Inflammatory Markers in Type 2 Diabetes: Relevance for Cardiovascular Risk Prevention显示文摘 | Rajkovic Natasa Zamaklar Miroslava Lalic Katarina Jotic Aleksandra Lukic Ljiljana Milicic Tanja Singh Sandra Stosic Ljubica Lalic Nebojsa M | 2014 | International Journal of Environmental Research and Public Health2014，，4： | 1 |
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