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| 1 | Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis. | Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski | 2019 | World Journal of Gastroenterology2019,25,48: | 8 |
| 2 | Utstein-style guidelines for uniform reporting of laboratory CPR research显示文摘 | Ahamed H Idris Lance B Becker | 1996 | Resuscitation1996,33,1: | 1 |
| 3 | An empirical study of applied game theory: Transmission constrained Cournot behavior显示文摘 | Lance B C Ross B Martin L B | 2002 | IEEE Transactions on Power Systems2002,17,1: | 1 |
| 4 | Recognizes veterinary shortage in public health 显示文摘 | JESSUP D A KARESH W B LANCE W R | 2005 | J Am Vet bled Assoc2005,227,3: | 1 |
| 5 | XX/XY Chimerism and Freemartinism in a Female Llama Co - twin to a Male显示文摘 | Katrin H Lance C Buoen B S | 1999 | Journal of the American Veterinary Medical Association1999,215,8: | 1 |
| 6 | Utstein - style guidelines for uniform reporting of laboratory CPR research 显示文摘 | Ahamed H Idris Lance B Becker | 1996 | Resuscitation1996,33,1: | 1 |
| 7 | Microchip capillary electrophoresis with an integrated postcolumn reactor显示文摘 | STEPHEN C J LANCE B K ROLAND H | 1994 | Anal Chem1994,66,20: | 1 |
| 8 | Characterization of commercial EB-PVD TBC systems with CVD(Ni,Pt) Al bond coatings显示文摘 | HAYNES J A LANCE M J PINT B A WRIGHT I G | 2001 | Surface and Coatings Technology2001,,: | 1 |
| 9 | The Application of SHRIMP to Phanerozoic geochronology: a critical appraisal of four zircon standards显示文摘 | Lance P B Sandra L K Ian S Williams | 2003 | Chemical Geology2003,200,: | 1 |
| 10 | TEMORA 1: a new zircon standard for Phanerozoic U-Pb geochronology显示文摘 | Lance P B Sandra L K Charlotte M A | 2003 | Chemical Geology2003,200,: | 1 |
| 11 | Thomas goetzen electrophilic tetraal-kylammonium nitrate nitration显示文摘 | SCOTT A SHACKELFORD MARK B ANDERSON LANCE C CHRISTIE | 2003 | Org Chem2003,68,2: | 1 |
| 12 | Steroid levels and reproduc- tive cycle of the Galapagos tortoise, Geochelone nigra, living under seminatural conditions on Santa Cruz Island (Galapagos) 显示文摘 | Schramm B G Casares M Lance V A | 1999 | Gen Comp Endocrinol1999,114,: | 1 |
| 13 | Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in eardiomvoeytes显示文摘 | TERRY L VANDEN HOEK LANCE B | 1998 | J Biol Chem1998,273,18: | 1 |
| 14 | TEMORA 1:a new zircon standard for Phanerozoic U-Pb geochronology显示文摘 | Lance P B Sandra L K Charlotte M A | 2003 | Chemical Geology2003,200,: | 1 |
| 15 | Root aeration improves yield and water use efficiency of tomato in heavy day and saline soils 显示文摘 | Surya P B Lance P David J M | 2006 | Science Phalopathyentia Horticulturae2006,108,: | 1 |
| 16 | Acquisition or greenfield start-up? Institutional, cultural and transaction cost influences 显示文摘 | Keith D B Lance E B | 2000 | Strategic Management Jour-nal2000,21,13: | 1 |
| 17 | TEMORA 1: a new zircon standard for Phanerozoic U-Pb geochronology显示文摘 | Lance P B Sandra L K Charlotte M A | 2003 | Chemical Geology2003,200,12: | 1 |
| 18 | Therole of a9 desat-urase in the production ofcis 9, trans 11 CLA 显示文摘 | Benjamin A C Lance H B Debra A D | 2001 | Journal of Nutritional Biochemistry2001,,12: | 1 |
| 19 | XX/XY Chimerism and freemartinism in a female llama co-twin to a male显示文摘 | Lance C Buoen B S | 1999 | J Am Vet Med Assoc1999,25,8: | 1 |
| 20 | Utstein-style guidelines for uniform reporting of laboratory CPR research 显示文摘 | Ahamed H Lance B Becker T | 1996 | Resuscitation1996,33,1: | 1 |