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| 1 | Renin-angiotensin system in the kidney: What is new?显示文摘The renin-angiotensin system(RAS)has been known for more than a century as a cascade that regulates body fluid balance and blood pressure.AngiotensinⅡ(AngⅡ)has many functions in different tissues;however it is on the kidney that this peptide exerts its main functions.New enzymes,alternative routes for AngⅡformation or even active AngⅡ-derived peptides have now been described acting on AngⅡAT1or AT2receptors,or in receptors which have recently been cloned,such as Mas and AT4.Another interesting observation was that old members of the RAS,such as angiotensin converting enzyme(ACE),renin and prorenin,well known by its enzymatic activity,can also activate intracellular signaling pathways,acting as an outside-in signal transduction molecule or on the renin/(Pro)renin receptor.Moreover,the endocrine RAS,now is also known to have paracrine,autocrine and intracrine action ondifferent tissues,expressing necessary components for local AngⅡformation.This in situ formation,especially in the kidney,increases AngⅡlevels to regulate blood pressure and renal functions.These discoveries,such as the ACE2/Ang-(1-7)/Mas axis and its antangonistic effect rather than classical deleterious AngⅡeffects,improves the development of new drugs for treating hypertension and cardiovascular diseases. | Fernanda M Ferr?o Lucienne S Lara Jennifer Lowe | 2014 | World Journal of Nephrology2014，3，3： | 5 |
| 2 | Efficient metallization of magnetite concentrate by reduction with agave bagasse as a source of reducing agents显示文摘The reduction behavior and metallization degree of magnetite concentrate with agave bagasse were investigated in an inert atmosphere.The effects of temperature,biomass content,and residence time on reduction experiments and metallization degree were investigated by X-ray diffraction and scanning electron microscopy.Compared with other types of biomass,agave bagasse had lower contents of nitrogen,sulfur,and ash.X-ray diffraction analysis showed that the metallization degree improved with increasing temperature and biomass content.Complete metallization was achieved at 1100℃ for 30 min with 65:35 and 50:50 ratios of the magnetite concentrate to the agave bagasse.These results demonstrate that agave bagasse promotes the efficient metallization of magnetite concentrate without the external addition of a reducing agent.Therefore,this biomass is a technical suitable alternative to replace fossil fuels in steelmaking. | Diana Cholico-González NoemíOrtiz Lara Mario Alberto Sánchez Miranda Ricardo Morales Estrella Ramiro Escudero García Carlos ALeón Patiño | 2021 | International Journal of Minerals,Metallurgy and Materials2021，28，4： | 2 |
| 3 | Clean recovery of antioxidant flavonoids from citrus peel:optimizing an aqueous ultrasound-assisted extraction method显示文摘 | Londono-Londono J Delima VR Lara O | | 0，，01： | 1 |
| 4 | A survey on human activity recognition using wearable sensors 显示文摘 | Lara O D Labrador M A | 2013 | IEEE Communications Surveys & Tu- torials2013，15，3： | 1 |
| 5 | Quantum Study of the Li + HF → LiF + H Reaction显示文摘 | AGUADO A PANIAGUA M LARA M RONCERO O | 1997 | Journal of Chemi- cal Physics1997，107，10： | 1 |
| 6 | Adaptive fuzzy Petri nets for dynamic knowledge representation and inference显示文摘 | Li X O Yu W Lara F R | 2000 | Expert Systems with Application2000，30，4： | 1 |
| 7 | A simple method for real-time DSP-based neutron-chopper speed and phase control显示文摘 | ROSE C R LARA P D NELSON R O | 2001 | Proceedings of the Particle Accelera- tor Conference2001，，： | 1 |
| 8 | Biomarkers of DNA repair and related pathways: significance in non-small cell lung cancer显示文摘 | Rothschild SI Gautschi O Lara PN Jr | 2011 | Curr Opin Oncol2011，23，2： | 1 |
| 9 | Effects of body size and home range on access to mates and paternity in male bridled naihail wallabies 显示文摘 | Fisher D O Lara M C | 1999 | Anim Behav1999，58，： | 1 |
| 10 | A power system stabi- lizer for DFIG - based wind generation 显示文摘 | Hughes F M Anaya lara O Jenkins N | 2006 | IEEE Trans on Power systems2006，24，3： | 1 |
| 11 | Automated Di- agnosis of Rolling Bearings Using MRA and Neural Networks显示文摘 | Castejon C Lara O Garcia Prada J C | 2010 | Mechanical Systems and Signal Processing2010，24，1： | 1 |
| 12 | Automated diagnosis of rolling bearings using MRA and neural networks显示文摘 | Castejon C Lara O Carcia-Prada J C | 2010 | Mechanical Systems and Signal Processing2010，24，1： | 1 |
| 13 | Dynamic knowledge inference and learning under adaptive fuzzy Petri net framework显示文摘 | Li X O Yu W Lara Rosano F | 2000 | Systems Man and Cybernetics - Part C2000，30，4： | 1 |
| 14 | Phosphorus stress in common bean: root transcript and metabolic, responses 显示文摘 | Hern6ndez G Ramirez M Valdes-L6pez O Tesfaye M Graham M A Czechowski T Schlereth A Wandrey M Erban A Cheung F Wu H C Lara M Town C D Kopka J Udvardi M K Vance C P | 2007 | Plant Physiol2007，144，： | 1 |
| 15 | On the influence of the number of objectives on the hardness of a multiobjective optimization problem显示文摘 | Schutze O Lara A Coello C A C | 2011 | IEEE Transactions on Evolutionary Computation2011，15，4： | 1 |
| 16 | Biochemicaland proteomic analysis of 'Dixiland' peach fruit (Prunus persica) upon heat treatment 显示文摘 | Lara M V Borsani J Budde C O | 2009 | J Exp Bot2009，60，： | 1 |
| 17 | Living with heteroge neities in bioreactors: Understanding the effects of environ mental gradients on cells 显示文摘 | Lara A R Galindo E Ramirez O | 2006 | Molecular Biotechnology2006，34，3： | 1 |
| 18 | A survey on human activity recogni- tion using wearable sensors显示文摘 | Lara O D Labrador M A | 2013 | Communications Surveys : Tu- torials IEEE2013，15，11： | 1 |
| 19 | Embedded control system for a four-rotor UAV显示文摘 | S Salazar-Cruz J Escare o D Lara | 2007 | International Journal of Adaptive Control and Signal Processing2007，21，23： | 1 |
| 20 | Sintering of glasses in the system RO-Al2O3-BaO-SiO2 (R=Ca, Mg, Zn) studied by hot-stage microscopy显示文摘 | LARA C PASCUAL M J PRADO M O | 2004 | Solid State Ionics2004，170，： | 1 |
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