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| 1 | Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review显示文摘Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, however many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma was performed and information on the topic was gathered. In this article, we present an extensive review of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator with better overall survival than HPV-negative tumours. A distinct group of younger patients with limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. However, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities. | Robbie SR Woods Esther M O'Regan Susan Kennedy Cara Martin John J O'Leary Conrad Timon | 2014 | World Journal of Clinical Cases2014，2，6： | 5 |
| 2 | 爱尔兰海洋经济和资源显示文摘什么是爱尔兰?
这或许是个奇怪的问题。目前还很少有人认为爱尔兰是一个海洋国家。如果有人认为爱尔兰由9万平方公里的陆域面积和90万平方公里的海域面积组成,就更加稀奇了。 | Y Shields J O’Cornor J O’Leary 周怡圃 王占坤 羊志洪 | 2010 | 经济资料译丛2010，，1： | 4 |
| 3 | The adaptive significance of amphistomatic leaves 显示文摘 | Mott K A Gibson A G O'Leary J W | 1982 | Plant Cell Environ1982，9，： | 2 |
| 4 | Leukocyte and Bacterial Counts Do Not Correlate With Severity of Symptoms in Men With Chronic Prostatitis: The National Institutes of Health Chronic Prostatitis Cohort Study显示文摘 | Anthony J. Schaeffer Jill S. Knauss J. Richard Landis Kathleen J. Propert Richard B. Alexander Mark S. Litwin J. Curtis Nickel Michael P. O’leary Robert B. Nadler Michel A. Pontari Daniel A. Shoskes Scott I. Zeitlin Jackson E. Fowler Carissa A. Mazurick J | 2002 | The Journal of Urology2002，，3： | 2 |
| 5 | The bleachability of wheat straw alkaline peroxide mechanical pulp显示文摘 | Pan George X Leary Gordon J | 2000 | Cellulose chemistry and technology2000，34，56： | 1 |
| 6 | Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose:bio-blots显示文摘 | Leary J L Brigati D J Ward D C | 1983 | Proc Natl Acad Sci USA1983，80，： | 1 |
| 7 | A knowledge - basedapproach to response surface modeling in multifidelity optimization显示文摘 | LEARY S J BHASKAR A KEANE A J | 2003 | Journal of Global Optimization2003，26，3： | 1 |
| 8 | BRAFV600E: implications for carcinogenesis and mo lecular therapy显示文摘 | Cantwell ER O ' Leary J J Sheils OM | 2011 | Mol Cancer Ther2011，10，38： | 1 |
| 9 | Characterization of phycocyanin produced by cpcE and cpcF mutants and identification of an intergenic suppressor of the defect in bilin attachment显示文摘 | Swanson R V Zhou J Leary J A | 1992 | J Biol Chem1992，267，16： | 1 |
| 10 | A constraint mapping approach to the structural optimization of an expensive model using surrogates显示文摘 | LEARY S J BHASKAR A KEANE A J | 2001 | Optimization and Engineering2001，2，38： | 1 |
| 11 | The role of ferulic acid removalduring bleaching of wheat straw mechanical pulp with peroxygen reagents显示文摘 | Pan G X Thomson C I Leary G J | 2003 | Holzforschung2003，57，3： | 1 |
| 12 | Gastrointestinal stromal tumor workshop显示文摘 | Berman J O'Leary TJ | 2001 | Hum Pathol2001，32，5： | 1 |
| 13 | Urea for preservation of moist hay显示文摘 | Henning J C Dougherty C T Leary J | 1990 | Anim Feed Sci Technol1990，31，34： | 1 |
| 14 | Phosphoenolpyruvate earboxylase:a ubiquitous,highly regulated enzyme in plants显示文摘 | Chollet R Vidal J O'Leary M H | 1996 | Ann Rer Plant Physiol Plant Mol Biol1996，47，： | 1 |
| 15 | Improved detection systems for TY virus reveal high prevalence in humans, non - human primates and farm animals 显示文摘 | LEARY T P ERKER J C CHALMERS M L | 1999 | J Gen Virol1999，80，： | 1 |
| 16 | Regulation of ribosome biogenesis with in the nueleolus 显示文摘 | Leary D J Huang S | 2001 | FEBS Lett2001，509，： | 1 |
| 17 | Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma显示文摘 | Finn S P Smyth P O' Leary J | 2003 | J Clin Endocrinol Metab2003，88，： | 1 |
| 18 | A statistical overview of mass movement characteristics on the North American Atlantic outer continental margin 显示文摘 | Booth J M O Leary D W | 1991 | Marine Geotechnology1991，10，： | 1 |
| 19 | Activation of nonspecific cytotoxic cells with a multiple antigenic peptide: Specificity and requirements for receptor crosslinkage 显示文摘 | JasoFriedmann L Leary J H Weisman Z | 1996 | Cellular Immunology1996，170，2： | 1 |
| 20 | A means-end investigation of ropes course experiences显示文摘 | Goldenberg M A Klenosky D B O' Leary J T | 2000 | Journal of Leisure Research2000，32，2： | 1 |
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