|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biological therapy in inflammatory bowel diseases:Access in Central and Eastern Europe显示文摘Biological drugs opened up new horizons in the management of inflammatory bowel diseases(IBD).This study focuses on access to biological therapy in IBD patients across 9 selected Central and Eastern European(CEE)countries,namely Bulgaria,the Czech Republic,Estonia,Hungary,Latvia,Lithuania,Poland,Romania and Slovakia.Literature data on the epidemiology and disease burden of IBD in CEE countries was systematically reviewed.Moreover,we provide an estimation on prevalence of IBD as well as biological treatment rates.In all countries with the exception of Romania,lower biological treatment rates were observed in ulcerative colitis(UC)compared to Crohn’s disease despite the higher prevalence of UC.Great heterogeneity(up to 96-fold)was found in access to biologicals across the CEE countries.Poland,Bulgaria,Romania and the Baltic States are lagging behind Hungary,Slovakia and the Czech Republic in their access to biologicals.Variations of reimbursement policy may be one of the factors explaining the differences to a certain extent in Bulgaria,Latvia,Lithuania,and Poland,but association with other possible determinants(differences in prevalence and incidence,price of biologicals,total expenditure on health,geographical access,and cost-effectiveness results)was not proven.We assume,nevertheless,that healthdeterioration linked to IBD might be valued differently against other systemic inflammatory conditions in distinct countries and which may contribute to the immense diversity in the utilization of biological drugs for IBD.In conclusion,access to biologicals varies widely among CEE countries and this difference cannot be explained by epidemiological factors,drug prices or total health expenditure.Changes in reimbursement policy could contribute to better access to biologicals in some countries. | Fanni Rencz Márta Péntek Martin Bortlik Edyta Zagorowicz Tibor Hlavaty Andrzej Sliwczyński Mihai M Diculescu Limas Kupcinskas Krisztina B Gecse László Gulácsi Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，6： | 4 |
| 2 | A hysteretic model for a vanadium dioxide transitionedge microbolometer显示文摘 | de Almeida L A L L Deep G S Lima A M N | 2001 | IEEE Trans Instrum Meas2001，50，4： | 2 |
| 3 | Effects of resistance training on the lipid profile in obese women显示文摘 | Costa R R Lima Alberton C Tagliari M Martins Kruel L F | 2011 | Journal of Sports Medicine and Physical Fitness2011，，1： | 2 |
| 4 | Photochemical responses and oxidative stress in the clones of Coffea canephora under water deficit conditions显示文摘 | Lima A L S DaMatta F M Pinheiro H A | 2002 | Environmental and Experimental Botany2002，47，23： | 1 |
| 5 | Photochemical responses and oxidative stress in two clones of Coffea canephora under water deficit conditions显示文摘 | LIMA A L S DAMATT F M PINHEIRO H A | 2002 | Environmental and Experimental Botany2002，47，： | 1 |
| 6 | Third-generation nephrectomy by natural orifice transluminal endoscopic surgery显示文摘 | Lima E Rolanda C Pego J M Henriques-Coelho T Silva D Osorio L | 2007 | J Urol2007，178，： | 1 |
| 7 | Identification, expression and phylogenetic analysis of the Anticarsia gemmatalis, multicapsid nucleopolyhedrovirus ( AgMNPV ) helicase 显示文摘 | Lima L Pinedo F J Ribeiro B M | 2004 | Virus Genes2004，29，： | 1 |
| 8 | Groundwater Vulnerability Assessment Combining the Drastic and Dyna-Clue Model in the ArgentinePampas显示文摘 | Lima M L Zelaya K Massone H | 2011 | Environmental Management2011，47，5： | 1 |
| 9 | Study of catalyst deactivation and reaction mechanism of steam reforming,partial oxidation,and oxidative steam reforming of ethanol over Co/CeO2 catalyst显示文摘 | de Lima S M da Silva A M da Costa L O O | 2009 | J Catal2009，268，2： | 1 |
| 10 | Nanocasted oxides for gas phase glycerol conversion显示文摘 | LIMA C L VASCONCELOS S J S FILHO J M | 2011 | Appl Catal A: General2011，599，： | 1 |
| 11 | Model structure determination in neural network models显示文摘 | E L Lima D E Seborg | 2000 | Chemical Engineering Science2000，55，22： | 1 |
| 12 | Population dynamics of rice rats (a Hantavirus reservoir) in southern Chile: feedback structure and non-linear effects of climatic oscillations显示文摘 | Murua R Gonzalez L A Lima M | 2003 | Oikos2003，102，11： | 1 |
| 13 | Prevalence and nonrandom distribution of exonic mutations in inter-feron regulatory factor 6 in 307 families with Van der Woude syndrome and 37 families with popliteal pterygium syndrome显示文摘 | de LIMA R L HOPER S A GHASSIBE M | 2009 | Genet Med2009，11，： | 1 |
| 14 | A novel preisach operator for modeling of hysterisi in VO2 microbolometer显示文摘 | Almeida L A L Deep G S Lima A M N | 2002 | IEEE Instrumentation and Measurement Technology2002，1，2123： | 1 |
| 15 | Adsorption modeling of Cr,Cd and Cu on activa- ted carbon of different origins by using fractional factorial design 显示文摘 | De Lima L S Araujo M D M QuinOia S P | 2011 | Chemical Engineering Jour- nal2011，166，3： | 1 |
| 16 | A Mathematical model for evaluating the effect of wind on downward-spraying rainfall simulators显示文摘 | De Lima J L M P Torfs P J J F Singh V P | 2002 | Catena2002，46，4： | 1 |
| 17 | Armillaria paulensis : a new South American species 显示文摘 | Lima M L Asai T Capelari M | 2008 | Mycological Research2008，112，： | 1 |
| 18 | MW and Mvar management on supply and demand side for meeting voltage stability margin criteria显示文摘 | AFFONSO C M SILVA L C LIMA F G | 2004 | IEEE Trans on Power Systems2004，19，3： | 1 |
| 19 | A new Fusarium lineage within the Gibberellafujikuroi species complex is the main causal agent of mango malformation disease in Brazil显示文摘 | LIMA C S PFENNING L H COSTA S S CAMPOS M A LESLIE J F | 2009 | Plant Pathology2009，58，： | 1 |
| 20 | Particle filter with differential evolution for trajecttry tracking 显示文摘 | DE LIMA L M KROHLING R A | 2011 | Advances in Intelligent and Soft Computing2011，96，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员