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| 1 | Prospective validation of %p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4-10 ng ml-1显示文摘尽管有它为屏蔽的前列腺癌症的普遍使用,低特性使 PSA 成为非最优的 biomarker,特别在 4-10 ng ml 1 的诊断灰色的地区。假积极与伴随的病态导致不必要的活体检视。这在与在 4.0 和 10 ng ml 1 之间的全部的 PSA 介绍的亚洲人是 % p2PSA 和前列腺健康索引(PHI ) 的第一未来的确认研究。我们学习了在 50 和 75 岁之间的 157 个亚洲人,与每直肠的前列腺考试的正常,经历他们的第一前列腺活体检视,用一个标准化活体检视协议,为 4-10 ng ml 1 的 PSA 层次。(19.1%) 三十被发现在活体检视上有前列腺癌症。有或没有前列腺癌症的病人之间的统计上重要的差别被作出对有利的裁决全部的 PSA, p2PSA, % p2PSA,和 PHI。在为全部的 PSA, % fPSA, % p2PSA,和 PHI 操作典型曲线的接收装置的曲线下面的区域分别地是 0.479, 0.420, 0.695,和 0.794。PHI 最好预言 prostatic 活体检视结果。在 90% 的敏感, PHI 的特性(95% CI ) 是 58.3% ,多于在 17.3% 点使全部的 PSA 的特性增加两倍,潜在地避免 77 (49%) 不必要的活体检视。类似于研究在主要白种人人口,我们有希望地证明了 % p2PSA 和 PHI 极大地超过总数并且释放总计 PSA 比率,在前列腺癌症的察觉起初活体检视。更高的 PHI 层次也对应于增加检测 GS 7 癌症的风险。我们验证了 PHI 的使用与在 4 和 10 ng ml 1 之间的浆液 PSA 在亚洲人关于前列腺活体检视帮助决策。 | Lincoln GL Tan Yung Khan Tan Bee Choo Tai Karen ML Tan Vineet Gauhar Ho Yee Tiong Robert CW Hawkins Thomas P Thamboo Felicia SK Hong Edmund Chiong | 2017 | Asian Journal of Andrology2017，19，3： | 13 |
| 2 | A low frequency piezoelectric power harvester using a spiral-shaped bimorph显示文摘We propose a spiral-shaped piezoelectric bimorph power harvester operating with coupled flexural and extensional vibration modes for applications to low frequency energy sources. A theoretical analysis is performed and the computational results show that the spiral structure has relatively low operating frequency compared to beam power harvesters of the same size. It is found that to optimize the performance of a piezoelectric spiral-shaped harvester careful design is needed. | HU Yuantai1,2,HU Hongping2 & YANG Jiashi3 1. Institute of Mechanics and Sensing Technology,Central South University,Changsha 410083,China 2. Department of Mechanics,Huazhong University of Science and Technology,Wuhan 430074,China 3. Department of Engineering Mechanics,University of Nebraska,Lincoln,NE 68588-0526,USA | 2006 | Science China(Physics,Mechanics & Astronomy)2006，49，6： | 9 |
| 3 | 中国卫生人力资源:数量、质量和分布显示文摘在本文中,我们从数量、质量和分布的角度对中国现有的卫生人力资源进行了分析。与绝大多数国家不同,2005年中国拥有的医生总数大于护士总数——注册的执业医师和执业助理医师总数达190多万,注册的护士总数为140多万。城市地区的医生密度是农村地区的2倍多,而城市地区护士的密度是农村地区的3倍多。中国大多数医生(67.2%)和护士(97.5%)所接受的教育仅为大专或中专水平。自1998年以来,中国的医学卫生教育事业有了很大的发展,医学院校不断扩招又导致了卫生人员供过于求的局面。 | Sudhir Anand Victoria Y Fan Junhua Zhang Lingling Zhang Yang Ke Zhe Dang Lincoln C Chen | 2009 | 世界临床医学2009，3，1： | 9 |
| 4 | 中国慢性病的挑战与应对显示文摘中国在短短几十年内,完成了从传染病向慢性病的流行病学模式转变,转变速度远远高于其他许多国家。而行为模式的转变,包括膳食习惯变化、体力活动减少、高水平的男性吸烟率等危险因素是中国疾病模式快速转变的重要原因。其结果是,这些本可避免的慢性病的发病率和死亡率快速上升。引发了医疗卫生服务费用显著上升。目前,中国有1.77亿高血压患者,有3.03亿烟民(占世界烟民的1/3),并有5.3亿人遭受被动吸烟危害。 | Gonghuan Yang Lingzhi Kong Wenhua Zhao Xia Wan Yi Zhai Lincoln C Chen Jeffrey P Koplan | 2008 | 世界临床医学2008，2，6： | 5 |
| 5 | CT偶发肾上腺肿块的管理--美国放射学院(ACR)偶发病变委员会白皮书显示文摘美国放射学院(American College of Radiology,ACR)偶发病变委员会(Incidental Findings Committee,IFC)针对CT和MRI上偶然发现的肾上腺肿块,提出了新的管理建议。该建议是对美国放射学院杂志(JACR)2010版肾上腺、肾脏、肝脏及胰腺偶发病变管理白皮书中肾上腺部分的更新。由腹部放射科医师和1位内分泌外科医生组成的肾上腺亚组委员会制定了该方案。该方案结合已发表的文献和专家意见,经过反复推敲最终达成共识。该方案依据患者的特征和图像的特点对偶然发现的肾上腺肿块进行分类。对于每种特定的组合,总结良性或惰性的特征(足以终止随访),并提出后续管理建议。该方案涵盖了很多、但并非适用于所有的病理及临床情况,旨在通过提供肾上腺偶发肿块的管理意见以提升医疗质量。 | William W.Mayo-Smith Julie H.Song Giles L.Boland Isaac R.Francis Gary M.Israel Peter J.Mazzaglia Lincoln L.Berland Pari V.Pandharipande 张惠茅 胡道予 江新青 刘爱连 伍兵 | 2018 | 放射学实践2018，33，2： | 3 |
| 6 | Dietary approaches following endoscopic retrograde cholangiopancreatography: A survey of selected endoscopists显示文摘AIM: To describe the dietary recommendations of experienced endoscopists for patients who have undergone endoscopic retrograde cholangiopancreatography (ERCP) and the factors that influence these recommendations. METHODS: Selected U.S. endoscopists with ERCP experience were surveyed by e-mail. A questionnaire with three hypothetical ERCP cases of patients at low, medium and high risk for development of post-ERCP pancreatitis (PEP) was shown. For each scenario, respondents were asked to recommend a post-procedure diet and time to first oral intake. Respondents were also asked about the effect of various clinical factors on their recommendations, including risk of PEP.RESULTS: 97/187 selected ASGE members (51.9%) responded. When risk of PEP was either low, medium or high, 53%, 88% and 96% recommended a diet of clear liquids/NPO respectively, and 2%, 5% and 18% recommended delaying first oral intake until the following day. About 88% of respondents gave the same type of diet to patients at high as those with moderate-risk of PEP (P = 0.04). However, 37% and 43% of respondents gave different types of diet to patients at low vs moderate-risk and low-risk vs high-risk of PEP respectively (P < 0.001). No statistically significant associations were found regarding the effect of other clinical factors or respondent demographics.CONCLUSION: Most experienced endoscopists limit diet to NPO/clear liquids after ERCP for patients at high or moderate risk of post-ERCP pancreatitis. About half allow a low-fat or regular diet in patients at low risk. | Lincoln EVVC Ferreira Mark D Topazian William S Harmsen Alan R Zinsmeister Todd H Baron | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，12： | 3 |
| 7 | 帕金森病患者睡眠障碍——病例对照调查显示文摘目的 观察帕金森病 (Parkinson sdisease ,PD)患者出现睡眠障碍的频率及比较睡眠障碍与抗PD药物、情绪、PD运动障碍程度之间的关系。方法 随机病例 对照 ,量表方式调查了澳大利亚新南威尔士大学脑捐献中心非痴呆PD患者 5 2例、同龄非PD对照组 5 0例 ,为增加信息的可靠程度 9%被调查者采用直接会见方式、2 7%附加电话问询进一步确认症状的可靠性与准确性。结果 完成调查表者 38例PD患者和 32例年龄匹配的对照组均在社区居住。PD组与对照组比较有较多的白天过量嗜睡 ( 4 5 %比 6 % )、不安腿 ( 5 0 %比 19% )和睡眠异常运动 ( 34%比 0 % ) ,此类症状多在PD诊断后的 3~ 5年内发现。上述异常表现与患者情绪障碍及药物无关。结论 多数PD患者存在睡眠障碍 ,且发现这些症状多出现在PD诊断后平均 3~ 5年 ,L | 鲁佑瑜 王少石 JM Henderson Chen Lincoln | 2004 | 中国神经精神疾病杂志2004，30，3： | 3 |
| 8 | Successful endoscopic treatment of colonic gallstone ileus using electrohydraulic lithotripsy显示文摘The surgical management of gallstone ileus is complex and potentially highly morbid.Initial management requires enterolithotomy and is generally followed by fistula resection at a later date.There have been reports of gallstone extraction using various endoscopic modalities to relieve the obstruction,however,to date,there has never been a published case of endoscopic stone extraction from the colon using electrohydraulic lithotripsy.In this report,we present the technique employed to successfully perform an electrohydraulic lithotripsy for removal of a large gallstone impacted in the sigmoid colon.A cavity was excavated in an obstructing 4.1 cm lamellated stone in the sigmoid colon using electrohydraulic lithotripsy.A screw stent retractor and stent extractor bored a larger lumen which allowed for guidewire advancement and stone fracture via serial pneumatic balloon dilatation.The stone fragments were removed.Electrohydraulic lithotripsy is a safe and effective method to treat colonic obstruction in the setting of gallstone ileus. | Martin D Zielinski Lincoln E Ferreira Todd H Baron | 2010 | World Journal of Gastroenterology2010，16，12： | 2 |
| 9 | Predictors of itch and pain in the 12 months following burn injury:results from the Burns Registry of Australia and New Zealand(BRANZ)Long-Term Outcomes Project显示文摘Background:Itch and pain are common complaints of patients with burn injuries.This study aimed to describe the prevalence and predictors of itch and moderate to severe pain in the first 12 months following a burn injury,and determine the association between itch,moderate to severe pain,workrelated outcomes,and health-related quality of life following a burn injury.Methods:Burn patients aged 18 years and older were recruited from five Australian specialist burn units.Patients completed the 36-item Short Form Health Survey Version 2(SF-36 V2),the Sickness Impact Profile(SIP)work scale,and a specially developed questionnaire relating to itch at 1,6,and 12 months post-injury.Moderate to severe pain was defined as a score less than 40 on the bodily pain domain of the SF-36 V2.Multivariate mixed-effects regression models were used to identify patient and burn injury predictors of itch and moderate to severe pain.Results:Three hundred and twenty-eight patients were included.The prevalence of itch decreased from 50%at 1 month to 27%at 12 months.Similarly,the prevalence of moderate to severe pain decreased from 23%at 1 month to 13%at 12 months.Compared to patients aged 18-34,the adjusted odds of experiencing any itch were 59%(95%CI:0.20,0.82)and 55%(95%CI:0.22,0.91)lower for patients aged between 35 and 49 and≥50 years,respectively.Compared to patients aged 18-34,the adjusted odds of experiencing moderate to severe pain were 3.12(95%CI:1.35,7.20)and 3.42(95%CI:1.47,7.93)times higher for patients aged 35-49 and≥50 years,respectively.Conclusions:Less than 15%of patients reported moderate or severe pain at 12 months,while approximately one-quarter of the patients reported itch at the same period.The presence of moderate to severe pain was associated with a greater negative impact on health-related quality of life and work outcomes compared to itch.Further research is needed to improve our ability to identify patients at higher risk of persistent itch and pain who would benefit from targeted review and intervention studies. | Lincoln M.Tracy Dale W.Edgar Rebecca Schrale Heather Cleland Belinda J.Gabbe on behalf of the BRANZ Adult Long-Term Outcomes Pilot Project participating sites and working party | 2020 | Burns & Trauma2020，8，1： | 2 |
| 10 | A formulaic approach to translation at the post office: reading the signs显示文摘 | Alison Wray Stephen Cox Mike Lincoln Judy Tryggvason | 2003 | Language and Communication2003，，1： | 2 |
| 11 | Analytical and numerical modeling of resonant piezoelectric devices in China-A review显示文摘The results on theoretical and numerical modeling of resonant piezoelectric devices in China are reviewed. Solutions to dynamic problems of the propagation of bulk acoustic waves (BAW), surface acoustic waves (SAW), vibrations of finite bodies, and analyses of specific devices are discussed. Results from both the ultrasonics community and mechanics researchers are included. It is hoped that the paper will be useful for the understanding, communication and collaboration between Chinese and foreign scholars. The paper may also be helpful for bridging the gap between ultrasonics and mechanics researchers on piezoelectricity re- search. The paper contains 316 references. | YANG JiaShi1,2↑ & YANG ZengTao1 1 Institute of Mechanics and Sensing Technology, School of Civil Engineering and Architecture, Central South University, Changsha 410083, China 2 Department of Engineering Mechanics, University of Nebraska, Lincoln, NE 68588-0526, USA | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，12： | 2 |
| 12 | CT肝脏偶发病灶管理--美国放射学院(ACR)偶发病变委员会白皮书显示文摘美国放射学院(American College of Radiology,ACR)偶发病变委员会(Incidental Findings Committee,IFC)发布了关于肝脏CT偶发病灶的管理建议。这些建议是对ACR 2010年胰腺、肾上腺、肾脏及肝脏偶发病变管理白皮书中肝脏部分的更新。该方案由肝脏亚组委员会(包括5位腹部影像学专家,1位肝病学专家和1位肝胆外科医生)制定。这些建议结合已发表的文献及专家意见,并最终达成专家共识。该方案主要基于患者特征及影像学特征对肝脏病灶进行分类,评估终点为某种良性诊断或具体的随访建议。该方案适用于大多数病理或临床情况,但并非所有情况均适用。该方案旨在通过提供肝脏偶发病灶管理意见以提升医疗质量。 | Richard M.Gore Perry J.Pickhardt Koenraad J.Mortele Elliot K.Fishman Jeanne M.Horowitz Claus J.Fimmel Mark S.Talamonti Lincoln L.Berland Pari V.Pandharipande 宋彬 严福华 杨正汉 叶惠义 姜慧杰 | 2018 | 放射学实践2018，33，2： | 2 |
| 13 | 胰腺偶发囊肿的管理--美国放射学院(ACR)偶发病变委员会白皮书显示文摘美国放射学院(American College of Radiology,ACR)偶发病变委员会(Incidental Findings Committee,IFC)发布了CT或MR偶发胰腺囊肿的管理建议。该建议是对美国放射学院杂志(JACR)2010年发布的肾上腺、肾脏、肝脏以及胰腺偶发病变管理白皮书中胰腺部分的更新。该管理方案由多位腹部影像医师、1位胃肠道学医师以及1位胰腺外科医师所组成的胰腺亚组委员会制定。该方案参考已发表的文献和专家意见,经反复协商,最终达成共识。该方案的分支成功地根据患者的临床特点及影像特征将胰腺囊肿进行分类,评估终点为良性和/或进展缓慢病变的诊断(足以结束随访)或具体的管理建议。该方案适用于大多数但非全部的病理及临床情况。该方案旨在通过提供胰腺偶发囊肿的管理指导,来提高患者的管理质量。 | Alec J.Megibow Mark E.Baker Desiree E.Morgan Ihab R.Kamel Dushyant V.Sahani Elliot Newman William R.Brugge Lincoln L.Berland Pari V.Pandharipande 赵心明 曾蒙苏 薛华丹 刘再毅 石喻 | 2018 | 放射学实践2018，33，2： | 2 |
| 14 | 公猪阉割术的末路与动物福利问题显示文摘对于养猪业而言,小公猪的阉割一直是涉及动物福利的主要问题。但手术阉割有利于去除公猪膻味,减少其对生产不利的雄性行为.因此如何废除手术阉割同时保留这一手段的积极作用是亟待解决的一个关键问题. | 张贤群 Nigel Lincoln | 2012 | 国外畜牧学(猪与禽)2012，，12： | 2 |
| 15 | Venous thromboembolism prophylaxis practice and its association with outcomes in Australia and New Zealand burns patients显示文摘Background:Patients with burn injuries are considered to have an increased risk of venous thromboembolism(VTE).While untreated VTEs can be fatal,no studies have examined chemoprophylaxis effectiveness.This study aimed to quantify the variation in prevalence of VTE prophylaxis use in patients in Australian and New Zealand burns units and whether prophylaxis use is associated with in-hospital outcomes following burn injury.Methods:Admission data for adult burns patients(aged≥16 years)admitted between 1 July 2016 and 31 December 2018 were extracted from the Burns Registry of Australia and New Zealand.Mixed effects logistic regression modelling investigated whether VTE prophylaxis usewas associated with the primary outcome of in-hospital mortality.Results:There were 5066 admissions over the study period.Of these patients,81%(n=3799)with a valid response to the VTE prophylaxis data field received some form of VTE prophylaxis.Use of VTE prophylaxis ranged from 48.6%to 94.8%of patients between units.In-hospital death was recorded in<1%of patients(n=33).After adjusting for confounders,receiving VTE prophylaxis was associated with a decrease in the adjusted odds of in-hospital mortality(adjusted odds ratio=0.21;95%CI,0.07–0.63;p=0.006).Conclusions:Variation in the use of VTE prophylaxis was observed between the units,and prophylaxis use was associated with a decrease in the odds of mortality.These findings provide an opportunity to engage with units to further explore differences in prophylaxis use and develop future best practice guidelines. | Lincoln M.Tracy Peter A.Cameron Yvonne Singer Arul Earnest Fiona Wood Heather Cleland Belinda J.Gabbe | 2021 | Burns & Trauma2021，9，1： | 2 |
| 16 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 17 | 为什么要发展教育研究型卫生系统?显示文摘2012年11月,美国中华医学基金会(China Medical Board,CMB)联合复旦大学在上海共同主办了以加强中国教育研究型卫生系统(academichealthsystem,AHS)为主题的第四届西湖论坛。近200位学术界与政界领导出席了本届论坛,在其所提供的平台上,推出了强化和协调中国教育系统与卫生系统的概念基础和运作规则。 | Lincoln C.Chen 蒋茜(译) | 2013 | 中国循证医学杂志2013，13，5： | 2 |
| 18 | Energetic-protein supplementation in the last 60 days of gestation improves performance of beef cows grazing tropical pastures显示文摘Background: Nutrition is one of the most important factors that affect animal performance, and it therefore also impacts on financial results in beef systems. In this way, finding the best strategy for feeding supplements is of paramount importance. Aiming to evaluate the effect of supplement feeding strategies for beef cows in the last third of gestation, two experiments were conducted. In Experiment 1, 35 pregnant Nellore cows were assigned to a completely randomized design with four treatments: control, which received no supplement; supplementation for the last 30 d of gestation(30-d; 3.0 kg/d); supplementation for the last 60 d of gestation(60-d; 1.5 kg/d); or supplementation for the last 90 d of gestation(90-d; 1.0 kg/d). All supplemented treatments received the same total amount of supplement throughout the experiment: 90 kg(20% of crude protein). A second experiment(Experiment 2) was delineated to evaluate the effects of the amounts offered in Experiment 1 on intake and metabolism. Four multiparous pregnant Nellore cows were assigned to a 4 × 4 Latin square design, with periods of15 d each.Results: There was a linear effect of the number of days of supplementation on calving body weight(BW; P < 0.05)and a quadratic effect on BW change from parturition to d 31 post-calving(P < 0.05), with cows on the 60-d strategy losing less BW post-calving. No difference was found in offspring birth BW(P > 0.10). A significant linear effect on interval from parturition to conception(P < 0.05) was observed, with the highest calving to conception interval being observed in the 90-d strategy. The level of supplementation did not affect forage intake or neutral detergent fiber digestibility(P > 0.10). Nitrogen excreted through urine tended to increase linearly with the level of supplementation(P < 0.10).Conclusion: Providing 1.5 kg of supplement during the last 60 d of gestation improves cow performance after calving, reducing the magnitude of BW lost, and reduces the number of days from calving to re-conception in the following breeding season compared to the usually recommended period of supplementation of 90 d pre-partum. | Aline Gomes da Silva Mário Fonseca Paulino Edenio Detmann Henrique Jorge Fernandes Lincoln da Silva Amorim Román Enrique Maza Ortega Victor Valério de Carvalho Josilaine Aparecida da Costa Lima Felipe Henrique de Moura Mariana Benevides Monteiro Jéssika Almeida Bitencourt | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 2 |
| 19 | Parkinson's disease : a rethink of rodent models 显示文摘 | Melrose H L Lincoln S J Tyndall G M Farrer M J | 2006 | Exp Brain Res2006，173，： | 1 |
| 20 | Complex relationship between Parkin mutations and Parkinson' s disease 显示文摘 | West A Periquet M Lincoln S | 2002 | Med Genet2002，114，5： | 1 |
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