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| 1 | Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions显示文摘Genotyping and phenotyping large natural populations provide opportunities for population genomic analysis and genome-wide association studies(GWAS). Several rice populations have been re-sequenced in the past decade;however, many major Chinese rice cultivars were not included in these studies. Here, we report large-scale genomic and phenotypic datasets for a collection mainly comprised of 1,275 rice accessions of widely planted cultivars and parental hybrid rice lines from China. The population was divided into three indica/Xian and three japonica/Geng phylogenetic subgroups that correlate strongly with their geographic or breeding origins. We acquired a total of 146 phenotypic datasets for 29 agronomic traits under multi-environments for different subpopulations. With GWAS, we identified a total of 143 significant association loci, including three newly identified candidate genes or alleles that control heading date or amylose content. Our genotypic analysis of agronomically important genes in the population revealed that many favorable alleles are underused in elite accessions, suggesting they may be used to provide improvements in future breeding efforts. Our study provides useful resources for rice genetics research and breeding. | Xiuxiu Li Zhuo Chen Guomin Zhang Hongwei Lu Peng Qin Ming Qi Ying Yu Bingke Jiao Xianfeng Zhao Qiang Gao Hao Wang Yunyu Wu Juntao Ma Liyan Zhang Yongli Wang Lingwei Deng Shanguo Yao Zhukuang Cheng Diqiu Yu Lihuang Zhu Yongbiao Xue Chengcai Chu Aihong Li Shigui Li Chengzhi Liang | 2020 | Science China(Life Sciences)2020，63，11： | 8 |
| 2 | Molecular characteristics of three thymosin-repeat proteins from Marsupenaeus japonicus and their responses to WSSV infection显示文摘β-thymosins, a family of highly conserved peptides, play a vital role in wound-healing, angiogenesis,antimicrobial process and antiviral immunity. Three novel β-thymosin-repeat proteins, named mjthm4, mjthm3 and mjthm2, were cloned from Marsupenaeus japonicus using expressed sequence tags(EST) from suppression subtractive hybridization. The mjthm4, mjthm3 and mjthm2 c DNAs possessed open reading frames that encoded166, 128 and 90 amino acid residue polypeptides and contained four, three and two β-thymosin actin binding modules, respectively. Blast analysis demonstrated that mjthm4, mjthm3 and mjthm2 shared high homology with known invertebrate multi-repeat β-thymosins. These proteins are ubiquitously expressed in all of the examined tissues, and the transcriptional levels were highest in the intestine. Further investigation revealed that mjthm4,mjthm3 and mjthm2 were remarkably up-regulated 6 h after WSSV infection. Moreover, while mjthm4 transcriptional levels displayed no changes, mjthm3 and mjthm2 levels decreased in the virus-resistant shrimps.The results indicate that mjthm4, mjthm3 and mjthm2 are novel multi-repeat β-thymosin homologues, have a close relationship with WSSV infection, and might contribute to a better understanding of host defense and/or virus invasion interactions in shrimps. | MA Jinyou RUAN Lingwei XU Xun GAO Zhaoming | 2016 | Acta Oceanologica Sinica2016，35，4： | 5 |
| 3 | Enhanced magnetic properties in chemically inhomogeneous Nd-Dy-Fe-B sintered magnets by multi-main-phase process显示文摘Homogeneous substitution of Dy for Nd in the hard magnetic 2:14:1 phase can effectively enhance coercivity to ensure the high temperature operation,however,inevitably deteriorate remanence at expense.In this work,we performed a comparative investigation of the two magnets prepared by multimain-phase(co-sintering Nd_(2)Fe_(14)B and(Nd,Dy)_(2)Fe_(14)B powders)and single-main-phase(sintering(Nd,Dy)_(2)Fe_(14)B powders)approaches.The comparative investigation reveals that at the same Dy substitution level(2.16 wt%),such chemically inhomogeneous multi-main-phase magnet possesses better roomtemperature magnetic properties as well as thermal stability than those of the single-main-phase one with homogenous Dy distribution in the matrix grains.Room-temperature magnetic properties H_(Cj)=1664 kA/m,B_(r)=1.33 T and(BH)_(max)=350.4 kJ/m^(3)for the multi-main-phase magnet are all better than those for the single-main-phase magnet with H_(Cj)=1536 kA/m,B_(r)=1.29 T and(BH)_(max)=318.4 kj/m^(3).In addition,over the temperature range from 295 to 423 K,both the temperature coefficients of coercivity and remanence for the multi-main-phase magnet are also lower than that for the single-main-phase magnet.Such superior magnetic performance is attributed to the short-range magnetic interactions inside individual 2:14:1 phase grains and the long-range magnetostatic interactions between adjacent grains with inhomogeneous Dy distribution.Our work provides a feasible approach of enhancing coercivity and retaining energy product simultaneously in the Nd-Dy-Fe-B permanent magnets. | Xiaolian Liu Mengjie Pan Pei Zhang Tianyu Ma Lizhong Zhao Lingwei Li | 2021 | Journal of Rare Earths2021，39，5： | 5 |
| 4 | Amoxicillin effects on functional microbial community and spread of antibiotic resistance genes in amoxicillin manufacture wastewater treatment system显示文摘This study aimed to reveal how amoxicillin(AMX) affected the microbial community and the spread mechanism of antibiotic resistance genes(ARGs) in the AMX manufacture wastewater treatment system. For this purpose, a 1.47 L expanded granular sludge bed(EGSB) reactor was designed and run for 241 days treating artificial AMX manufacture wastewater. 454 pyrosequencing was applied to analyze functional microorganisms in the system. The antibiotic genes OXA_(-1), OXA_(-2), OXA_(-10), TEM_(-1), CTX-M_(-1), class I integrons(intI1) and 16 SrRNA genes were also examined in sludge samples. The results showed that the genera Ignavibacterium, Phocoenobacter,Spirochaeta, Aminobacterium and Cloacibacillus contributed to the degradation of different organic compounds(such as various sugars and amines). And the relative quantification of eachβ-lactam resistance gene in the study was changed with the increasing of AMX concentration.Furthermore the vertical gene transfer was the main driver for the spread of ARGs rather than horizontal transfer pathways in the system. | Lingwei Meng Xiangkun Li Xinran Wang Kaili Ma Gaige Liu Jie Zhang | 2017 | Journal of Environmental Sciences2017，29，11： | 5 |
| 5 | Achievement of promising cryogenic magnetocaloric performances in La_(1-x)Pr_(x)Fe_(12)B_(6)compounds显示文摘The magnetic refrigeration(MR)utilizing magnetocaloric effect(MCE)has been recognized as an environmentally friendly and energy efficiency technology.Here we presented the magnetic properties and MCE in Pr-doped La_(1-x)Pr_(x)Fe_(12)B_(6)(x=0.05-0.2)itinerant-electron metamagnetic(IEM)compounds.A small amount of Pr doping La site can greatly improve the peak values in the magnetic entropy change S_(M)(T)curves,especially under relatively low magnetic field changes(ΔH).Additionally,the peak temperature increases gradually and the magnetic hysteresis reduces gradually with increasing x.The observed MCE in present La_(1-x)Pr_(x)Fe_(12)B_(6)compounds is related to its field-induced first-ordered IEM transition.The peak values ofΔS_(M)for La_(1-x)Pr_(x)Fe_(12)B_(6)compounds reach 13.4,15.4,12.5 and 13.0 J/(kg K)at T_(C)~58,68,72and 89 K for x=0.05,0.10,0.15 and 0.2 under H of 0-7 T,respectively.The corresponding relative cooling power values are 462.3,480.7,372.4 and 375.7 J/kg.The present La_(1-x)Pr_(x)Fe_(12)B_(6)compounds could be good candidates for active MR application if the magnetic and thermal hysteresis can be further reduced.The present work indicates that the La Fe_(12)B_(6)-based material system could also exhibit promising magnetocaloric performances. | Zhipan Ma Xiaoshi Dong Zhenqian Zhang Lingwei Li | 2021 | Journal of Materials Science & Technology2021，，33： | 4 |
| 6 | Vapor-hydrate phases equilibrium of (CH_4+C_2H_6) and (CH_4+C_2H_4) systems显示文摘Separation of the(C1+C2)hydrocarbon system is of importance in natural gas processing and ethylene production.However it is the bottleneck because of its high refrigeration energy consumption, and needs to be urgently addressed.The technology of separating gas mixtures by forming hydrate could be used to separate(C 1 +C 2 )gas mixtures at around 0°C and has attracted increasing attention worldwide.In this paper,investigation of vapor-hydrate two-phase equilibrium was carried out for(C 1 +C 2 )systems with and without tetrahydrofuran(THF).The compositions of vapor and hydrate phases under phase equilibrium were studied with model algorithm when structure I and structure II hydrates coexisted for the(methane+ethane)system.The average deviation between the modeled and actual mole fractions of ethane in hydrate and vapor phases was 0.55%,and that of ethylene was 5.7%when THF was not added.The average deviation of the mole fraction of ethane in vapor phase was 11.46%and ethylene was 7.38%when THF was added.The test results showed that the proposed algorithm is practicable. | Ma Qinglan Chen Guangjin Zhang Lingwei | 2008 | Petroleum Science2008，5，4： | 4 |
| 7 | Microbiologically influenced corrosion of 304 stainless steel by halophilic archaea Natronorubrum tibetense显示文摘The corrosion behavior of 304 stainless steel(SS)in the presence of aerobic halophilic archaea Natronorubrum tibetense was investigated.After 14 days of immersion,no obvious pitting pit was observed on the SS surface in the sterile medium.By contrast,the SS exhibited serious pitting corrosion with the largest pit depth of 5.0μm in the inoculated medium after 14 days.The results of electrochemical tests showed that the barrier property of the passive film decreased faster in the inoculated medium.The X-ray photoelectron spectroscopy results indicated that the detrimental Fe2+and Cr6+increased in the passive film under the influence of archaea N.tibetense,which resulted in the accelerated deterioration of passive film and promoted the pitting corrosion.Combined with the energy starvation tests,the microbiologically influenced corrosion mechanism of 304 SS caused by halophilic archaea N.tibetense was discussed finally. | Hongchang Qian Lingwei Ma Dawei Zhang Ziyu Li Luyao Huang Yuntian Lou Cuiwei Du | 2020 | Journal of Materials Science & Technology2020，42，11： | 3 |
| 8 | Photothermal and pH dual-responsive self-healing coating for smart corrosion protection显示文摘A novel self-healing coating with photothermal and pH dual-responsive properties has been designed to protect carbon steel against corrosion by loading the stimuli-responsive microcapsules into a shape memory epoxy coating. The sandwich-like microcapsules were based on reduced graphene oxide/mesoporous silica(r GO@MS) assembled with a p H-responsive poly(N,N-dimethylaminoethyl methacrylate)(PDMAEMA) layer, and were loaded with benzotriazole(BTA) inhibitors(abbreviated as rGO@MS-P-BTA). Under near-infrared(NIR) light irradiation, the prominent photothermal effect of rGO could not only elevate the coating temperature to activate the shape memory effect and close the coating scratch, but also facilitate the release of corrosion inhibitors to suppress the corrosion activity. Moreover,the PDMAEMA as a p H-driven “gatekeeper” realized the controlled release of BTA from microcapsules at acid conditions. The surface morphology analysis, electrochemical impedance spectroscopy(EIS), and scanning electrochemical microscopy(SECM) were performed to evaluate the self-healing performance of the composite coatings. The results showed that the combination of NIR light and p H-responsive selfhealing effects endowed the coating with short healing time and prominent healing efficiency. | Yao Huang Panjun Wang Weimin Tan Wenkui Hao Lingwei Ma Jinke Wang Tong Liu Fan Zhang Chenhao Ren Wei Liu Dawei Zhang | 2022 | Journal of Materials Science & Technology2022，，12： | 2 |
| 9 | Multi-action self-healing coatings with simultaneous recovery of corrosion resistance and adhesion strength显示文摘In this study, a new self-healing strategy that can simultaneously recover the corrosion resistance and the adhesion strength of coatings was introduced. The coating was based on a shape memory epoxy resin containing ethylene vinyl acetate(EVA) microspheres loaded with Ce(NO_(3))_(3)inhibitors, and was cured at a relatively high temperature to facilitate the fusion of adjacent microspheres for a strengthened self-healing effect. The electrochemical impedance spectroscopy(EIS) and scanning electrochemical microscopy(SECM) results demonstrated that the shape memory effect of epoxy matrix, the filling of molten EVA microspheres as well as the release of Ce(NO_(3))_(3)inhibitors contributed synergistically to suppress the corrosion reaction at the coating damage. After healing, the low frequency impedance modulus of the coatings containing Ce(NO_(3))_(3)-EVA microspheres was three orders of magnitude higher than that of the blank epoxy coating. The adhesion strength of the coatings containing Ce(NO_(3))_(3)-EVA microspheres on the metal substrate was also largely repaired thanks to the strong bonding effect of the EVA microspheres. | Chenhao Ren Yao Huang Wenkui Hao Dawei Zhang Xiejing Luo Lingwei Ma Jinke Wang Thee Chowwanonthapunya Chaofang Dong Xiaogang Li | 2022 | Journal of Materials Science & Technology2022，，6： | 2 |
| 10 | Neuromorphic sensory computing显示文摘The number of sensory nodes in the Internet of everything continues to increase rapidly and generate massive data.The generated information from sensory nodes is much larger than the total collective human sensory throughput.It is quite challenging to send all of the data produced at sensory terminals to the“Cloud”computation center,especially for those time-delay sensitive applications.This situation demands a dramatic increase in the computation near or inside sensory networks.Inspired by biological sensory systems with a high data compression ratio,neuromorphic sensory computing provides a way to efficiently acquire and process a large volume of data from complex environments.Researchers have been investigating emerging materials,devices,circuits,and computing architectures to implement an artificial sensory system with high energy efficiency,speed,and density.Here we summarize the important features of biological systems and their hardware implementations.Electrons and photons are two representative information carriers,in which electron carrier allows high integration density for complex computing and photon carrier has high connectivity,high speed,wide bandwidth,and low power consumption.We overview the electronic and optical neuromorphic sensory computing and hybrid opto-electronic sensory computing,and present advances on multimodal sensory computing and their potential challenges. | Tianqing WAN Sijie MA Fuyou LIAO Lingwei FAN Yang CHAI | 2022 | Science China(Information Sciences)2022，65，4： | 2 |
| 11 | Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and MEK1/2显示文摘Constitutive activation of RAS-RAF-MEK-ERK signaling pathway(MAPK pathway)frequently occurs in many cancers harboring RAS or RAF oncogenic mutations.Because of the paradoxical activation induced by a single use of BRAF or MEK inhibitors,dual-target RAF and MEK treatment is thought to be a promising strategy.In this work,we evaluated erianin is a novel inhibitor of CRAF and MEK1/2 kinases,thus suppressing constitutive activation of the MAPK signaling pathway induced by BRAF V600E or RAS mutations.KinaseProfiler enzyme profiling,surface plasmon resonance(SPR),isothermal titration calorimetry(ITC),cellular thermal shift assay,computational docking,and molecular dynamics simulations were utilized to screen and identify erianin binding to CRAF and MEK1/2.Kinase assay,luminescent ADP detection assay,and enzyme kinetics assay were investigated to identify the efficiency of erianin in CRAF and MEK1/2 kinase activity.Notably,erianin suppressed BRAF V600E or RAS mutant melanoma and colorectal cancer cell by inhibiting MEK1/2 and CRAF but not BRAF kinase activity.Moreover,erianin attenuated melanoma and colorectal cancer in vivo.Overall,we provide a promising leading compound for BRAF V600E or RAS mutant melanoma and colorectal cancer through dual targeting of CRAF and MEK1/2. | Penglei Wang Xuechao Jia Bingbing Lu Han Huang Jialin Liu Xuejiao Liu Qiong Wu Yamei Hu Pan Li Huifang Wei Tingting Liu Dengyun Zhao Lingwei Zhang Xueli Tian Yanan Jiang Yan Qiao Wenna Nie Xinli Ma Ruihua Bai Cong Peng Zigang Dong Kangdong Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 1 |
| 12 | Acute toxicity and effects of 1-alkyl-3- methylimidazolium bromide ionic liquids on green algae显示文摘 | Ma Jianmin Cai Linlin Zhang Bangjun Hu Lingwei Li Xiaoyu Wang Jianji | 2010 | Ecotoxicology and Environmental Safety2010，73，： | 1 |
| 13 | A Study on the Cooperative Mechanism of the Belt and Road Initiative from the Perspective of New Regionalism显示文摘The loosely-typed, duty-overlapped and subject-isolated cooperative mechanism of the Belt and Road Initiative has significantly limited the advancement of the initiative and affected the full play of its cooperative effect. New Regionalism is a theory of international relations that concerns international cooperation at the regional level. Its characteristics of multilevel, multi-topic and multi-subject conform to the cooperation needs of the Belt and Road Initiative and provide a guiding framework for the cooperative mechanism of the Initiative. According to the theoretical connotation of New Regionalism, the cooperative mechanism of the Belt and Road Initiative should enrich its cooperation forms, deepen cooperation topics and promote the participation of 'State-Market-Society'. This mechanism is expected to form various cooperation models, comprehensive governance and diversified participants to enable the smooth advancement of the Belt and Road Initiative. | Deng Tingting Ma Chunxue Wu Lingwei | 2018 | Contemporary Social Sciences2018，3，1： | 1 |
| 14 | Functionalized carbon dots for corrosion protection:Recent advances and future perspectives显示文摘Metal corrosion causes significant economic losses,safety issues,and environmental pollution.Hence,its prevention is of immense research interest.Carbon dots(CDs)are a new class of zero-dimensional carbon nanomaterials,which have been considered for corrosion protection applications in recent years due to their corrosion inhibition effect,fluorescence,low toxicity,facile chemical modification,and cost-effectiveness.This study provides a comprehensive overview of the synthesis,physical and chemical properties,and anticorrosion mechanisms of functionalized CDs.First,the corrosion inhibition performance of different types of CDs is introduced,followed by discussion on their application in the development of smart protective coatings with self-healing and/or self-reporting properties.The effective barrier formed by CDs in the coatings can inhibit the spread of local damage and achieve self-healing behavior.In addition,diverse functional groups on CDs can interact with Fe^(3+)and H^(+)ions generated during the corrosion process;this interaction changes their fluorescence,thereby demonstrating self-reporting behavior.Moreover,challenges and prospects for the development of CD-based corrosion protection systems are also presented. | Li Zhao Jinke Wang Kai Chen Jingzhi Yang Xin Guo Hongchang Qian Lingwei Ma Dawei Zhang | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，11： | 0 |
| 15 | Long-term deterioration of lubricant-infused nanoporous anodic aluminium oxide surface immersed in NaCl solution显示文摘This study investigated the deterioration of a lubricant-infused anodic aluminium oxide surface in a 1M NaCl solution for~200 days.Direct observation by cryo-SEM and quantitative analyses by UV spectroscopy and EIS revealed that the long-term deterioration of the lubricant-infused surface was divided into two stages:the surface-adhered lubricant layer gradually dissolved at a constant rate until the substrate was exposed;afterwards the lubricant infused in the nanochannels began to diffuse and was depleted after~200 days.The EIS results also revealed that the defects reduced the corrosion resistance of the lubricant-infused surface considerably. | Dequan Wu Lingwei Ma Bei Liu Dawei Zhang Badar Minhas Hongchang Qian Herman A.Terryn Johannes M.C.Mol | 2021 | Journal of Materials Science & Technology2021，，5： | 0 |
| 16 | Tetraamido-oxacalix[4]arene Derivatives: Synthesis, Structures and Supramolecular Assemblies显示文摘Tetraamido-oxacalix [4 ] arene 衍生物经由 tetraamino-oxacalix 的反应被综合了[4 ] 有过量 butyryl 氯化物, octanoyl 氯化物, benzoyl 氯化物和 p-toluenesulfonyl 氯化物的 arene 分别地。1H NMR 结果建议那这些 oxacalix [4 ] arene 衍生物优先地采用 1,3 替换物(像僵绳) 在答案的符合构造,它也是处于由单个水晶 X 光检查分析示威了的稳固的状态的盒子。使聚合成二聚物的滑动的囊能被 tetra-butyramido-oxacalix 形成[4 ] 处于经由在二的帮助下面的分子间的氢契约相互作用的稳固的状态的 arene 包含了甲醇分子。在另一方面,一个分子的洞被 tetra-p-toluenesulfonamido-oxacalix 形成[4 ] 能包含乙醇醋酸盐的一个溶剂分子的 arene。 | Lingwei Kong Mingliang Ma Xiaoli Zhao Yahua Liu Xianqiang Mi Biao Jiang Ke Wen | 2013 | Chinese Journal of Chemistry2013，31，5： | 0 |
| 17 | Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum显示文摘Plants belonging to the genus Taraxacum are widespread all over the world,which contain rubber-producing and non-rubberproducing species.However,the genomic basis underlying natural rubber(NR)biosynthesis still needs more investigation.Here,we presented high-quality genome assemblies of rubber-producing T.kok-saghyz TK1151 and non-rubber-producing T.mongolicum TM5.Comparative analyses uncovered a large number of genetic variations,including inversions,translocations,presence/absence variations,as well as considerable protein divergences between the two species.Two gene duplication events were found in these two Taraxacum species,including one common ancestral whole-genome triplication and one subsequent round of gene amplification.In genomes of both TK1151 and TM5,we identified the genes encoding for each step in the NR biosynthesis pathway and found that the SRPP and CPT gene families have experienced a more obvious expansion in TK1151 compared to TM5.This study will have large-ranging implications for the mechanism of NR biosynthesis and genetic improvement of NR-producing crops. | Tao Lin Xia Xu Huilong Du Xiuli Fan Qingwen Chen Chunyan Hai Zijian Zhou Xiao Su Liquan Kou Qiang Gao Lingwei Deng Jinsheng Jiang Hanli You Yihua Ma Zhukuan Cheng Guodong Wang Chengzhi Liang Guomin Zhang Hong Yu Jiayang Li | 2022 | Science China(Life Sciences)2022，65，3： | 0 |
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