维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

4篇 您的检索式：作者名="Lisa Rossi"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells显示文摘AIM:To investigate effects of iron on oxidative stress, heme oxygenase-1(HMOX1)and hepatitis C viral(HCV) expression in human hepatoma cells stably expressing HCV proteins. METHODS:Effects of iron on oxidative stress,HMOX1, and HCV expression were assessed in CON1 cells. Measurements included mRNA by quantitative reverse transcription-polymerase chain reaction,and protein levels by Western blots. RESULTS:Iron,in the form of ferric nitrilotriacetate,increased oxidative stress and up-regulated HMOX1 gene expression.Iron did not affect mRNA or protein levels of Bach1,a repressor of HMOX1.Silencing the up-regulation of HMOX1 nuclear factor-erythroid 2-related factor 2(Nrf2)by Nrf2-siRNA decreased FeNTA-mediated up-regulation of HMOX1 mRNA levels.These iron effects were completely blocked by deferoxamine(DFO).Iron also significantly decreased levels of HCV core mRNA and protein by 80%-90%, nonstructural 5A mRNA by 90%and protein by about 50%in the Con1 full length HCV replicon cells, whereas DFO increased them. CONCLUSION:Excess iron up-regulates HMOX1 and down-regulates HCV gene expression in hepatoma cells.This probably mitigates liver injury caused by combined iron overload and HCV infection.	Wei-Hong Hou Lisa Rossi Ying Shan Jian-Yu Zheng Richard W Lambrecht Herbert L Bonkovsky	2009	World Journal of Gastroenterology2009，15，36：	5
	2	The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer显示文摘	Edgard Graner Dan Tang Sabrina Rossi Antonella Baron Toshiro Migita Lisa J Weinstein Mirna Lechpammer Dieter Huesken Johann Zimmermann Sabina Signoretti Massimo Loda	2004	Cancer Cell2004，，3：	1
	3	The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer显示文摘	Edgard Graner Dan Tang Sabrina Rossi Antonella Baron Toshiro Migita Lisa J Weinstein Mirna Lechpammer Dieter Huesken Johann Zimmermann Sabina Signoretti Massimo Loda	2004	Cancer Cell2004，，3：	1
	4	Imatinib inhibits in vitro proliferation of cells derived from a pleural solitary fibrous tumor expressing platelet-derived growth factor receptor-beta显示文摘	Marco Prunotto Martino Bosco Lorenzo Daniele Luigia Macri’ Lisa Bonello Laura Schirosi Giulio Rossi Pierluigi Filosso Baudolino Mussa Anna Sapino	2008	Lung Cancer2008，，2：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费