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| 1 | How important is donor age in liver transplantation?显示文摘The age of liver donors has been increasing in the past several years because of a donor shortage. In the United States, 33% of donors are age 50 years or older, as are more than 50% in some European countries. The impact of donor age on liver transplantation(LT) has been analyzed in several studies with contradictory conclusions. Nevertheless, recent analyses of the largest databases demonstrate that having an older donor is a risk factor for graft failure. Donor age is included as a risk factor in the more relevant graft survival scores, such as the Donor Risk Index, donor age and Model for End-stage Liver Disease, Survival Outcomes Following Liver Transplantation, and the Balance of Risk. The use of old donors is related to an increased rate of biliary complications and hepatitis C virus-related graft failure. Although liver function does not seem to be significantly affected by age, the incidence of several liver diseases increases with age, and the capacity of the liver to manage or overcome liver diseases or external injuries decreases. In this paper, the importance of age in LT outcomes, the role of donor age as a risk factor, and the influence of aging on liver regeneration are reviewed. | Alberto Lué Estela Solanas Pedro Baptista Sara Lorente Juan J Araiz Agustin Garcia-Gil M Trinidad Serrano | 2016 | World Journal of Gastroenterology2016，22，21： | 10 |
| 2 | Inhibition of nitric oxide synthesis improves the vasoconstrictive effect of noradrenalline in sepsis显示文摘 | Landin L Lorente J A Renes E | 1994 | Chest1994，106，1： | 2 |
| 3 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 4 | Environmental performance as an operations objective显示文摘 | De Burgos J J Lorente J J C | 2001 | International Journal of Operations & Production Management2001，21，12： | 1 |
| 5 | An analysis of environmental management, organizational context and performance of Spanish hotels显示文摘 | M.J álvarez Gil J Burgos Jiménez J.J Céspedes Lorente | 2001 | Omega2001，，： | 1 |
| 6 | Multiple - center ,randomized, placebo - controlled, double - blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock显示文摘 | Lopez A Lorente JA Steingrub J | 2004 | Crit Care Med2004，32，： | 1 |
| 7 | Sequencing of agents in castration-resistant prostate cancer显示文摘 | Lorente D Mateo J Perez-Lopez R | 2015 | Lancet Oncol2015，16，： | 1 |
| 8 | The role of PET scan in diagnosis,staging,and management of non-small cell lung cancer显示文摘 | Schrevens L Lorent N Dooms C Vansteenkiste J | 2004 | Oncologist2004，9，： | 1 |
| 9 | An improved method to recover saliva from human skin:the double swab technique显示文摘 | Lorente M Lorente J A | 1997 | J Forensic Sci1997，42，： | 1 |
| 10 | Bacterial filters in respiratory circuits:an unnecessary cost?显示文摘 | Lorente L Lecuona M Malaga J | 2003 | Crit Care Med2003，31，8： | 1 |
| 11 | Recent advances and applications of hyperspectral imaging for fruit and vegetable quality assessment显示文摘 | LORENTE D ALEIXOS N SANCHIS J G | 2012 | Food and Bioprocess Technology2012，5，4： | 1 |
| 12 | Limonene, linaloo|, alpha-terpineol, and terpinen-4-ol as quality control parameters in mandarin juice processing 显示文摘 | Perez-Lopez A J Saura D Lorente J | 2006 | European Food Research and Technology2006，222，34： | 1 |
| 13 | Evidence on measures for the prevention of ventilator - associated pneumonia显示文摘 | Lorente L Blot S Rello J | 2007 | Eur Respir J2007，30，3： | 1 |
| 14 | Relation between maximal rainfall rates for different time intervals in the course of a storm 显示文摘 | Lorente J | 1991 | Atmos Res1991，，7： | 1 |
| 15 | Antioxidant activity and radioprotective effects against chromosomal damage inducedin vivo by X-rays of flavan-3-ols (procyanidins) from grape seeds (Vitis vinifera): comparative study versus other phenolic and organic compounds显示文摘 | CASTILLO J BENAVENTE GARCIA O LORENTE J | 2000 | J Agric Food Chem2000，48，5： | 1 |
| 16 | Multi-center, randomized, placebo-controlled, double blind study of the nitric oxide synthase inhibitor 546C88:effect on survival in patients with septic shock(Abstract) 显示文摘 | Lopez A Lorente J | 1999 | Crit Care Med1999，，： | 1 |
| 17 | Effect of antibiotic treatment on serum PSA and percent free PSA levels in patients with biochemical criteria for prostate biopsy and previous lower urinary tract infections显示文摘 | Lorente J A Arango O Bielsa O | 2002 | Int J Biol Markers2002，17，： | 1 |
| 18 | Limonene, linaool, a-terpineol, and terpinen-4-ol as quality control parameters in mandarin juice processing显示文摘 | PI~Ri~z-L6i EZ A J sAuRA D LORENTE J | 2006 | European Food Research and Technology2006，222，： | 1 |
| 19 | Evidence on measures for the prevention of ventilator-associated pneumonia显示文摘 | Lorente L Blot S Rello J | 2007 | Eur Respir J2007，30，6： | 1 |
| 20 | Limonene, linalool, α-terpineol, and terpinen-4-ol as quality conlrol parameters in mandarin juice processing显示文摘 | PEREZ-LOPEZ A J SAURA D LORENTE J | 2006 | Eur Food Res Tectmol2006，222，3： | 1 |
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