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| 1 | 前列腺癌治疗前后动态增强MRI评价显示文摘目的 :应用MRI和动态增强MRI药物代谢动力学模型评价前列腺癌治疗前后的疗效 ,确定MRI的价值。方法 :对 16例经组织学证实的前列腺癌分别在治疗前后进行常规和动态增强MRI检查。治疗分别为单纯激素替代治疗 (7例 )和激素替代治疗加外放射治疗 (9例 )。MRI检查常规应用GESignaAdvantage 1.5T超导磁共振成像仪 ,静脉注射Gd DTPA(0 .1mmol/kg体重 )。应用两室药物代谢动力学模型分别计算肿瘤病灶、前列腺良性增生和正常前列腺周围带的最大增强指数、对比剂吸收幅度、对比剂的交换率和对比剂分布指数。结果 :治疗前后PSA由 39.5 4ng/ml降为 10 .39ng/ml(P =0 .0 4 6 ) ,由MRI测量获得的肿瘤体积明显缩小 (2 .85cm3 至 0 .84cm3 ,P =0 .0 1) ,前列腺良性增生和正常前列腺周围带也明显缩小 (P <0 .0 1)。治疗前后肿瘤病灶最大增强指数和对比剂分布指数降低 ,但未见统计学差异 ;对比剂吸收幅度和交换率明显降低 (P =0 .0 0 4 ,0 .0 0 2 )。前列腺良性增生的最大增强指数和对比剂分布指数降低 (P =0 .2 84 ,0 .2 2 1) ;对比剂吸收幅度和交换率明显降低 (P =0 .0 1,0 .0 0 7)。正常周围带的对比剂吸收幅度、交换率和分布指数明显降低 (P=0 .0 0 3,0 .0 1,0 .0 4 )。结论 :动态增强MRI能够全面反映前列腺癌治疗前? | 王滨 Martin LOWRY Lindsay W TURNBULL | 2003 | 医学影像学杂志2003，13，4： | 5 |
| 2 | C-reactive protein as an outcome predictor for maintenance hemodialysis patients显示文摘 | LOWRIE E G | 1998 | Kidney Int1998，54，： | 1 |
| 3 | Multivariate exponentially weighted moving average controlchart显示文摘 | LOWRY G A WOODALL W H CHAMP G W | 1992 | Technometrics1992，34，1： | 1 |
| 4 | The variability of IPO initial remms显示文摘 | Lowry M Officer M S Schwert G W | 2010 | Journal of Finance2010，，2： | 1 |
| 5 | Urban effects on precipitation amount 显示文摘 | LOWRY W P | 1998 | Progress in Physical Geography1998，22，： | 1 |
| 6 | Magnetic susceptibility anisotropy, strain, and progressive deformation in Permian sediments from the Maritime Alps (France)显示文摘 | Kligfield R Owens W H Lowrie W | 1981 | EPSL1981，55，1： | 1 |
| 7 | Inverse magnetic fabric in deformed limestones of the Morcles Nappe,Switzerland显示文摘 | Ihmlé P F Hirt A Lowrie W | | 0，，12： | 1 |
| 8 | Is the IPO pricingprocess efficient ? 显示文摘 | Lowry M G W Schwert | 2004 | Journal of Financial Economics2004，，71： | 1 |
| 9 | Generation of human induced pluripotent stem cells from dermal fibroblasts 显示文摘 | Lowry W E Richter L Yachechko R | 2008 | PNAS2008，105，8： | 1 |
| 10 | Potential focusing projects and policy change显示文摘 | Lowry W | 2006 | The Policy Studies Journal2006，34，3： | 1 |
| 11 | A multivariate exponentially weighted moving average control charts显示文摘 | LOWRY C A WOODALL W H CHAMP C W | 1992 | Technometrics1992，34，1： | 1 |
| 12 | Is the IPO pricing process efficient? 显示文摘 | Lowry M Schwert G W | 2004 | Journal of Financial Econonfics2004，71，1： | 1 |
| 13 | Molecular evolution of the GATA family of transcription factors:conservation within the DNA-binding domain显示文摘 | LOWRY J A ATCHLEY W R | 2000 | J Mol Evol2000，50，2： | 1 |
| 14 | Conceptual models of nursing:international in scope and substance? The case of the Neuman systems model 显示文摘 | Lowry L W | 2004 | Nursing Science Quarterly2004，17，1： | 1 |
| 15 | Magnetic Susceptibility Anisotropy as a Strain Indicator in the Subbury Basin Ontratio显示文摘 | Kligfield R W Lowrie W Dalziel W D | 1977 | Tectonophysics1977，40，： | 1 |
| 16 | Defining the epithelial stem cell niche in skin显示文摘 | Tumbar T Guasch T Greco V Blanpain C Lowry W E Rendl M | 2004 | Science2004，303，： | 1 |
| 17 | A multivariate exponentially weighted moving average controlchart 显示文摘 | Technomet- Lowry C A Woodall W H Champ C W Rigdon S E | 1992 | Technometrics1992，34，： | 1 |
| 18 | A multivariate EWMA control chart显示文摘 | Lowry C A Woodall W H Champ C W | 1992 | Technometrics1992，34，1： | 1 |
| 19 | Effects of an outbreak Of avian encephalomyelitis(epidemic tremor)in a breeding flock显示文摘 | Taylor L W Lowry D C | 1955 | Poultry Science1955，34，： | 1 |
| 20 | Assessing critical thinking in baccalaureate nursing students: A longitudinal study显示文摘 | Beckie T M Lowry L W Barnett S | 2001 | Holi Nurs Prac2001，15，3： | 1 |
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