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| 1 | Comparison of the removal of COD by a hybrid bioreactor at low and room temperature and the associated microbial characteristics显示文摘 | Tianling Li Luji Bo Fan Yang Shanqing Zhang Yonghong Wu Linzhang Yang | 2012 | Bioresource Technology2012，，： | 2 |
| 2 | Multiomics approach reveals the ubiquitination-specific processes hijacked by SARS-CoV-2显示文摘The Coronavirus Disease 2019(COVID-19)caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)is a global pandemic that seriously threatens health and socioeconomic development,but the existed antiviral drugs and vaccines still cannot yet halt the spread of the epidemic.Therefore,a comprehensive and profound understanding of the pathogenesis of SARS-CoV-2 is urgently needed to explore effective therapeutic targets.Here,we conducted a multiomics study of SARS-CoV-2-infected lung epithelial cells,including transcriptomic,proteomic,and ubiquitinomic.Multiomics analysis showed that SARS-CoV-2-infected lung epithelial cells activated strong innate immune response,including interferon and inflammatory responses.Ubiquitinomic further reveals the underlying mechanism of SARS-CoV-2 disrupting the host innate immune response.In addition,SARS-CoV-2 proteins were found to be ubiquitinated during infection despite the fact that SARS-CoV-2 itself didn’t code any E3 ligase,and that ubiquitination at three sites on the Spike protein could significantly enhance viral infection.Further screening of the E3 ubiquitin ligases and deubiquitinating enzymes(DUBs)library revealed four E3 ligases influencing SARS-CoV-2 infection,thus providing several new antiviral targets.This multiomics combined with high-throughput screening study reveals that SARS-CoV-2 not only modulates innate immunity,but also promotes viral infection,by hijacking ubiquitination-specific processes,highlighting potential antiviral and anti-inflammation targets. | Gang Xu Yezi Wu Tongyang Xiao Furong Qi Lujie Fan Shengyuan Zhang Jian Zhou Yanhua He Xiang Gao Hongxiang Zeng Yunfei Li Zheng Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 1 |
| 3 | High areal capacity flexible sulfur cathode based on multi-functionalized super-aligned carbon nanotubes显示文摘Rational design of a robust carbon matrix has a profound impact on the performance of flexible/wearable lithium/sulfur batteries.Herein,we demonstrate a freestanding three-dimensional super-aligned carbon nanotube (SACNT) matrix reinforced with a multi-functionalized carbon coating for flexible,high-areal sulfur loading cathode.By employing the sulfur/nitrogen co-doped carbon (SNC)'glue',the joints in the SACNT scaffold are tightly welded together so that the overall mechanical strength of the electrode is significantly enhanced to withstand the repeated bending as well as the volume change during operation.The SNC also shows intriguing catalytic effect that lowers the energy barrier of Li ion transport,propelling a superior redox conversion efficiency.The resulting binder-free and current collector-free sulfur cathode exhibits a high reversible capacity of 1,079 mAh·g^-1 at 1 C,a high-rate capacity of ~ 800 mAh·g^-1 at 5 C,and an average capacity decay rate of 0.037% per cycle at 2 C for 1,500 cycles.Impressively,a large-areal flexible Li/S pouch cell based on such mechanically robust cathode exhibits excellent capacity retention under arbitrary bending conditions.With a high areal sulfur loading of 7 mg·cm^-2,the large-areal flexible cathode delivers an outstanding areal capacity of 6.3 mAh·cm^-2 at 0.5 C (5.86 mA·cm^-2),showing its promise for realizing practical high energy density flexible Li/S batteries. | Lujie Jia Jian Wang Zijin Chen Yipeng Su Wei Zhao Datao Wang Yang Wei Kaili Jiang Jiaping Wang Yang Wu Jia Li Wenhui Duan Shoushan Fan Yuegang Zhang | 2019 | Nano Research2019，12，5： | 0 |
| 4 | A mixed culture of Propionibacterium freudenreichii and Lactiplantibacillus plantarum as antifungal biopreservatives in bakery product显示文摘In this study,15 strains of Lactic acid bacteria(Allata et al.)and 6 strains of propionic acid bacteria(PAB)were firstly tested for their antifungal activity against three spoilage fungi,Aspergillus niger,Penicillium crustosum and Aspergillus flavus.Two strains of LAB and PAB were selected and assessed,alone or paired,for their abilities to inhibit the most resistant mold,Aspergillus niger.A mixed culture of P.freudenreichii D6 and L.plantarum L9 was found to be the most active and their optimal inoculum was 1×10^(8) and 1×10^(6) CFU/mL,respectively.Furthermore,the in situ antifungal effect of the mixed culture was evaluated against bakery product spoilage fungi.It was found that the growth of airborne fungi was delayed for up to 7 days.The cell number of L.plantarum L9 was slightly increased by the presence of P.freudenreichii D6.Quantification of three main acids(propionic,lactic and acetic acid)produced by the protective cultures suggested that acetic acid was mainly responsible for the antifungal activity.In conclusion,the mixed culture of P.freudenreichii and L.plantarum may be exploited as biopreservatives in bakery products. | Qiong Ran Fan Yang Min Geng Lujie Qin Zhongyi Chang Hongliang Gao Deming Jiang Chunjing Zou Caifeng Jia | 2022 | Food Bioscience2022，47，3： | 0 |
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