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| 1 | Structure and mechanism of inhibition of plant acetohydroxyacid synthase显示文摘 | Ronald G. Duggleby Jennifer A. McCourt Luke W. Guddat | 2007 | Plant Physiology and Biochemistry2007，，3： | 1 |
| 2 | Molecular Basis of Sulfonylurea Herbicide Inhibition of Acetohydroxyacid Synthase 显示文摘 | Siew Siew Pang Luke W Guddat Ronald G Duggleby | 2003 | The Journal of Biological Chemistry2003，278，9： | 1 |
| 3 | Plant collagenase: Unique collagenolytic activity of cysteine proteases from ginger显示文摘 | Misook Kim Susan E Hamilton Luke W Guddat | 2007 | Biochimica et Biophysica Acta2007，，： | 1 |
| 4 | Plant collagenase: Unique collagenolytic activity of cysteine proteases from ginger显示文摘 | Misook Kim Susan E. Hamilton Luke W. Guddat Christopher M. Overall | 2007 | BBA - General Subjects2007，，12： | 1 |
| 5 | Structure-activity relationships for a new family of sulfonylurea herbicides显示文摘 | Jian-Guo Wang Zheng-Ming Li Ning Ma Bao-Lei Wang Lin Jiang Siew Siew Pang Yu-Ting Lee Luke W. Guddat Ronald G. Duggleby | 2005 | Journal of Computer - Aided Molecular Design2005，，11： | 1 |
| 6 | 结核分枝杆菌PknI激酶通过胞外传感器结构域二聚化被激活的结构研究显示文摘文章简介蛋白激酶对于宿主内结核分枝杆菌的存活起中心作用。课题组解析了丝氨酸/苏氨酸蛋白激酶(STPKs)家族里的跨膜蛋白成员Pkn I的传感器域(单体和二聚体形式)以及激酶域的高分辨率晶体结构。 | Qiaoling Yan Dunquan Jiang Lanfang Qian Qingqing Zhang Wei Zhang Weihong Zhou Kaixia Mi Luke Guddat Haitao Yang 饶子和 | 2018 | 科学新闻2018，0，4： | 0 |
| 7 | Structure-function Relationships in Human Hypoxanthine-guanine Phosphoribosyltransferase(HGPRT) by Random Mutagenesis显示文摘Hypoxanthine-guanine phosphoribosyltransferase(HGPRT, EC 2.4.2.8) is a key enzyme of the purine salvage pathway, which allows recycling of purine bases into DNA and RNA. It is widely distributed in nature and has been studied both in prokaryotes and eukaryotes. In humans, a complete lack of HGPRT activity causes the Lesch-Nyhan syndrome, which is characterized by hyperuricaemia and neural disorders, including mental retardation and compulsive self-mutilation behavior [1]. Partial deficiency of HGPRT activity may lead to gouty arthritis. Many parasites, such as Plasmodium falciparum, lack de novo purine nucleotide synthesis and make purine nucleotides only through salvage pathways. Hence, enzymes in salvage pathways are potential targets of therapeutic agents for treatment of parasitic diseases. | Luke Guddat Anthony Farlow John de Jersey | 2006 | Chemical Research in Chinese Universities2006，22，2： | 0 |
| 8 | Mammalian-like Purple Acid Phosphatases in Plants显示文摘Purple acid phosphatases(PAPs) comprise of a family of binuclear metal-containing hydrolases, some members of which have been isolated and characterized from animal, plant and fungal sources [1]. PAPs not only catalyze the hydrolyses of a wide range of phosphate esters and anhydrides under acidic reaction conditions, but also catalyze the generation of hydroxyl radicals in a Fenton-like reaction, by virtue of the presence of a redox-active binuclear metal center. Inmammals, the hydroxyl radicals so generated may be important for the degradation of connective tissue(in osteoclasts) and the defense against bacteria(in macrophages). Mammalian PAPs from several species have been isolated and characterized [1]. | John de Jersey FAN Hong-kuan Gary Schenk Luke Guddat Susan Hamilton | 2006 | Chemical Research in Chinese Universities2006，22，2： | 0 |
| 9 | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target显示文摘 | Qingqing Zhang Huijuan Liu Xiang Liu Dunquan Jiang Bingjie Zhang Hongliang Tian Cheng Yang Luke W. Guddat Haitao Yang Kaixia Mi Zihe Rao | 2018 | Protein & Cell2018，9，11： | 0 |
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