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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | Polymers containing quaternary ammonium groups based on poly ( N- vinylimidazole) 显示文摘 | CORNELIA L SILVIA M MARCEL P | 2002 | European Polymer Journal2002，38，8： | 1 |
| 3 | Percutaneous extraction of renal fungus ball显示文摘 | John M D Marc P B Marcelle J S | 1988 | A J R1988，150，： | 1 |
| 4 | Phage therapy reduces Campylobacterjejuni colonization in broilers显示文摘 | JAAP A W MARCEL A P V B MARK A M | 2005 | Veterinary Microbilogy2005，109，： | 1 |
| 5 | Induced parasitoid attraction by Arabidopsis thaliana:involvement of the octadecanoid and the salicylic acid pathway显示文摘 | Remco M P van Poecke Marcel D | 2002 | Journal of Experimental Botany2002，53，375： | 1 |
| 6 | Shrimp poly- culture: a potentially profitable,sustainable,but uncommon aq- uacuhuralpractice显示文摘 | MARCEL P M LUIS R M C MARCO P C | 2010 | RevAquac2010，2，2： | 1 |
| 7 | Development of an Array of Transition Edge Sensors for Application in X-ray Astronomy显示文摘 | Marcel P B Norman H R B Wouter M B T | 2004 | Nucl Instrum Meth A2004，520，： | 1 |
| 8 | The influence of executive cognition on competitive dynamics 显示文摘 | Marcel J J Barr P S Duhaime I M | 2011 | Strate- gic Management Journal2011，32，2： | 1 |
| 9 | β-Glucosidase: an elicitor of herbivore-induced plant odor that attracts host-searching parasitic wasps 显示文摘 | Letizia M Marcel D Maarten A P | 1995 | Proc Natl Acad USA1995，92，： | 1 |
| 10 | The Effect of Roads and Traffic on Hedgenhog (Erinaceus Europaeus) Populations 显示文摘 | Marcel P H Piet J M B | 2000 | Biological Conservation2000，95，： | 1 |
| 11 | Some molecular and colloidal aspects of tea cream formation显示文摘 | Marcel H G M P Donncha J P S Dave Needham | 1998 | Food Hydrocolloids1998，12，： | 1 |
| 12 | The effect of roads and traffic on hedgehog(Erinaceus europaeus)populations显示文摘 | Marcel P Huijser Piet J M Bergers | 2000 | Biological Conservation2000，95，： | 1 |
| 13 | Semiconductornanocrystals as fluorescent biological abels 显示文摘 | Marcel B J Mario M Alivisatos A P | 1998 | Science1998，281，5385： | 1 |
| 14 | Stromal myofibroblasts are drivers ofinvasive cancer growth显示文摘 | De Wever O Demetter P Marcel M | 2008 | IntJ Cancer2008，123，10： | 1 |
| 15 | A novel WRKY transcription factor is required for induction of PR-Ia gene expression by salicylic acid and bacterial elicitors 显示文摘 | Marcel C Van V Dimitfi P Lyda N John F B Huub J M L | 2008 | Plant Physiology2008，146，： | 1 |
| 16 | Preparation, purification, and characterization of aminopropyl-functionalized silica sol 显示文摘 | Marcell P Livia N N Judith M etal | 2013 | Colloid and Interface Science2013，390，： | 1 |
| 17 | Semiconductor nanocrystals as fluorescent biological labels显示文摘 | MARCEL B J MORONNE M GIN P | 1998 | Science1998，281，： | 1 |
| 18 | Semiconductor nanocrystals as fluorescent biological labels显示文摘 | Marcel B I Mario M Alivisatos A P | | 0，，： | 1 |
| 19 | 'Never eat in that restaurant, I did!' : Exploring why people engage in negative word-of- mouth communication显示文摘 | Wetzer l M Marcel Z Rik P | 2007 | Psychology & Marketing2007，24，8： | 1 |
| 20 | Stromal myofibroblasts are drivers of invasive cancer growth显示文摘 | De Wever O Demetter P Marcel M | 2008 | Int J Cancer2008，123，10： | 1 |
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