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| 1 | Orthotopic liver transplantation for giant liver haemangioma: A case report显示文摘In liver haemangiomas, the risk of complication rises with increasing size, and treatment can be obligatory. Here we present a case of a 46-year-old female who suffered from a giant haemangioma causing severe portal hypertension and vena cava compression, leading to therapy refractory ascites, hyponatremia and venostasis-associated thrombosis with pulmonary embolism. The patients did not experience tumour rupture or consumptive coagulopathy. Surgical resection was impossible because of steatosis of the non-affected liver. Orthotopic liver transplantation was identified as the only treatment option. The patient's renal function remained stable even though progressive morbidity and organ allocation were improbable according to the patient's lab model for end-stage liver disease(lab MELD) score. Therefore, non-standard exception status was approved by the European organ allocation network 'Eurotransplant'. The patient underwent successful orthotopic liver transplantation 16 mo after admission to our centre. Our case report indicates the underrepresentation of morbidity associated with refractory ascites in the lab MELD-based transplant allocation system, and it indicates the necessity of promptly applying for non-standard exception status to enable transplantation in patients with a severe clinical condition but low lab MELD score. Our case highlights the fact that liver transplantation should be considered early in patients with non-resectable, symptomatic benign liver tumours. | Undine G Lange Julian N Bucher Markus B Schoenberg Christian Benzing Moritz Schmelzle Tanja Gradistanac Steffen Strocka Hans-Michael Hau Michael Bartels | 2015 | World Journal of Transplantation2015，5，4： | 6 |
| 2 | Burden of Clostridium difficile infection between 2010 and 2013:Trends and outcomes from an academic center in Eastern Europe显示文摘AIM:To analyze the incidence and possible risk factors in hospitalized patients treated with Clostridium difficile infection(CDI).METHODS:A total of 11751 patients were admitted to our clinic between 1 January 2010 and 1 May2013.Two hundred and forty-seven inpatients were prospectively diagnosed with CDI.For the risk analysis a 1:3 matching was used.Data of 732 patients matched for age,sex,and inpatient care period and unit were compared to those of the CDI population.Inpatient records were collected from an electronic hospital database and comprehensively reviewed.RESULTS:Incidence of CDI was 21.0/1000 admissions(2.1%of all-cause hospitalizations and 4.45%of total inpatient days).The incidence of severe CDI was 12.6%(2.63/1000 of all-cause hospitalizations).Distribution of CDI cases was different according to the unit type,with highest incidence rates in hematology,gastroenterology and nephrology units(32.9,25 and24.6/1000 admissions,respectively) and lowest rates in 1.4%(33/2312) in endocrinology and general internal medicine(14.2 and 16.9/1000 admissions)units.Recurrence of CDI was 11.3%within 12 wk after discharge.Duration of hospital stay was longer in patients with CDI compared to controls(17.6 ± 10.8d vs 12.4 ± 7.71 d).CDI accounted for 6.3%of allinpatient deaths,and 30-d mortality rate was 21.9%(54/247 cases).Risk factors for CDI were antibiotic therapy[including third-generation cephalosporins or fluoroquinolones,odds ratio(OR) = 4.559;P < 0.001],use of proton pump inhibitors(OR = 2.082,P< 0.001),previous hospitaiization within 12 mo(OR = 3.167,P < 0.001),previous CDI(OR = 15.32;P < 0.001),while presence of diabetes mellitus was associated with a decreased risk for CDI(OR = 0.484;P< 0.001).Treatment of recurrent cases was significantly different from primary infections with more frequent use of vancomycin alone or in combination(P < 0.001),and antibiotic therapy duration was longer(P < 0.02).Severity,mortality and outcome of primary infections and relapsing cases did not significantly differ.CONCLUSION:CDI was accounted for significant burden with longer hospitaiization and adverse outcomes.Antibiotic,PPI therapy and previous hospitaiization or CDI were risk factors for CDI. | Zsuzsanna Kurti Barbara D Lovasz Michael D Mandel Zoltan Csima Petra A Golovics Bence D Csako Anna Mohas Lorant Gnczi Krisztina B Gecse Lajos S Kiss Miklos Szathmari Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，21： | 6 |
| 3 | Nerve Growth Factor and Artemin Are Paracrine Mediators of Pancreatic Neuropathy in Pancreatic Adenocarcinoma显示文摘 | Güralp O. Ceyhan Karl-Herbert Sch?fer Annika G. Kerscher Ulrich Rauch Ihsan Ekin Demir Mustafa Kadihasanoglu Carolin B?hm Michael W. Müller Markus W. Büchler Nathalia A. Giese Mert Erkan Helmut Friess | 2010 | Annals of Surgery2010，，5： | 2 |
| 4 | 2009年南极冰穹A的双色天光背景统计和分析显示文摘天光背景是天文台址的一个重要指标。利用2009年位于南极冰穹A的CSTAR望远镜两个波段的观测数据,对南极冰穹A的天光背景进行了统计和分析。结果表明约74%的g波段天光背景的ADU值小于每像素100/s;90.5%的r波段的天光背景的ADU值小于每像素100/s。在不考虑大气消光的情况下,定标后的结果为2009年冰穹A的观测数据中天光背景亮度的中值:g波段为19.9 mag/arcsec2,r波段为20.1 mag/arcsec2。 | 宗伟凯 付建宁 牛家树 Ashley Michael C B 宫雪非 Lawrence J S 刘强 Luong-Van Daniel Pennypacker C R Storey John W V 王灵芝 王力帆 杨惠根 袁祥岩 York Donald G 朱镇熹 | 2014 | 天文研究与技术2014，11，1： | 2 |
| 5 | The significance of sinistral portal hypertension complicating chronic pancreatitis显示文摘 | George H Sakorafas Michael G Sarr David R Farley Michael B Farnell | 2000 | The American Journal of Surgery2000，，2： | 2 |
| 6 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 7 | Phenotypic and genotypic differentiation of porcine Salmonella enterica sub spenterica serovar derby isolates显示文摘 | Michael G B Cardoso M Rabsch W | 2006 | Vet Microbiol2006，118，34： | 1 |
| 8 | Soil pits as a simple design aid for subsurface drip irrigation systems显示文摘 | Michael A B Bruce G S David G B | 2003 | Irrig Sci2003，22，： | 1 |
| 9 | HIV fusion and its inhibition in antiretroviral therapy显示文摘 | MICHAEL G B NIKE C M | 2004 | Rew Med Virol2004，14，： | 1 |
| 10 | What prognostic factors are important in duodenal adenocarcinoma显示文摘 | Faisal G B Michel M M Michael G S | 2000 | Arch Surg2000，135，1： | 1 |
| 11 | Determining the fluxes of Tl^+ and K^+ at the root surface of wheat and canola using Tl( I ) and K ion-selective microelectrodes显示文摘 | JAMES G H MICHAEL J O EDWARD B | 2010 | Plant Soil2010，335，1： | 1 |
| 12 | A contactless biometric system using multiple hand features 显示文摘 | MICHAEL G K O CONNIE T TEOH A B J | 2012 | Journal of Visual Communication and Image Representation2012，23，7： | 1 |
| 13 | Acute cholangitis and pancreatitis secondary to common duct stones: management update显示文摘 | MICHAEL G T RARATY M B MARGARET F | 1998 | World J Surg1998，22，： | 1 |
| 14 | Electrowetting-based actuation of liquid droplets for microfluidic applications显示文摘 | Michael G Pollack Richard B Fair Alexander D Shenderov | 2000 | Applied Physics Letters2000，77，11： | 1 |
| 15 | Comparative application of indices of biotic integrity basedon periphyton, macroinvertebrates, and fish to southernRocky Mountain streams显示文摘 | MICHAEL B G BRIAN H H FRANK H M | 2005 | Ecological Indicators2005，5，： | 1 |
| 16 | Application oftransient infrared and near infrared spectroscopy totransition metal complex excited states and inter-mediates显示文摘 | Jennifer M B Michael W G Jon R S | 2007 | Coord Chem Rev2007，251，： | 1 |
| 17 | Distant effect s of India Eurasia convergence and Mesozoic intracontinental deformation in Central Asia:Constraints from apatite fission-track thermo- chronology显示文摘 | Johan D G Michael M B Peter V H | 2006 | Journal of Asian Earth Sciences2006，，3： | 1 |
| 18 | Changes in connexin expression and the atrial fibrillation substrate in congestive heart failure 显示文摘 | Burstein B Comtois P Michael G | 2009 | Circ Res2009，105，12： | 1 |
| 19 | Risk-averse autono mous route guidance by a constrained A * search显示文摘 | Chen Y Michael G H B Klaus B | 2010 | Journal of Systems2010，14，3： | 1 |
| 20 | A contactless biometric system using multiple hand features 显示文摘 | MICHAEL G K O CONNIE T TEOH A B J | 2012 | Journal of Visual Communication and Image Representation2012，23，7： | 1 |
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