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73篇 您的检索式:作者名="MacDonald B T"
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1健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
2Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn’s disease-related perianal fistula显示文摘BACKGROUND Perianal fistulae are either primary(idiopathic)or secondary[commonly associated with Crohn’s disease,(CD)].It is assumed,although not proven,that the pathophysiology differs.AIM To systematically compare the clinical phenotypes,cytokine and phosphoprotein profiles of idiopathic and CD-related perianal fistulae.METHODS Sixty-one patients undergoing surgery for perianal fistula were prospectively recruited(48 idiopathic,13 CD)into a cohort study.Clinical data,including the Perineal Disease Activity Index(PDAI)and EQ-5D-5L were collected.Biopsies of the fistula tract,granulation tissue,internal opening mucosa and rectal mucosa were obtained at surgery.Concentrations of 30 cytokines and 39 phosphoproteins were measured in each biopsy using a magnetic bead multiplexing instrument and a chemiluminescent antibody array respectively.Over 12000 clinical and 23500 laboratory measurements were made.RESULTS The PDAI was significantly higher(indicating more active disease)in the CD group with a mean difference of 2.40(95%CI:0.52-4.28,P=0.01).Complex pathoanatomy was more prevalent in the CD group,namely more multiple fistulae,supralevator extensions,collections and rectal thickening.The IL-12p70 concentration at the internal opening specimen site was significantly higher(median difference 19.7 pg/mL,99%CI:0.2-40.4,P=0.008)and the IL-1RA/IL-1βratio was significantly lower in the CD group at the internal opening specimen site(median difference 15.0,99%CI=0.4-50.5,P=0.008).However in the remaining 27 cytokines and all 39 of the phosphoproteins across the four biopsy sites,no significant differences were found between the groups.CONCLUSION CD-related perianal fistulae are more clinically severe and anatomically complex than idiopathic perianal fistulae.However,overall there are no major differences in cytokine and phosphoprotein profiles.James B Haddow Omar Musbahi Thomas T MacDonald Charles H Knowles 2019World Journal of Gastrointestinal Pathophysiology2019,10,4:2
3文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
4医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K 2016中国卫生政策研究2016,9,4:1
5Wind-induced response and excitation characteristics of an inclined cable model in the critical Reynolds number range 显示文摘Jakobsen J B Andersen T L Macdonald J H G Nikitas N Larose G L Savagec M G McAuliffe B R 2012Journal of Wind Engineering and Industrial Aerodynamics2012,110,1:1
6Salinisation processes in a sub-catchment of Wybong Creek, Hunter Valley, Australia显示文摘Jasonsmith J F Macdonald B C T Mcphail D C 2011Australian Journal of Earth Sciences2011,2,:1
7Linking models and measurements of soil nitrogen emissions on a field scale 显示文摘Denmead O T Macdonald B C T Wang E Xing H Smith C J Chen D Turner D M 2012Soils Newsletter2012,34,1:1
8Wnt/beta- catenin signaling: components, mechanisms, and diseases显示文摘MACDONALD B T TAMAI K HE X 2009Dev Cell2009,17,1:1
9Wnt/β-catenin signaling:components,mechanisms,and diseases显示文摘MacDonald B T Tamai K He X 2009Dev Cell2009,17,1:1
10Wnt/beta - catenin signa- ling: components, mechanisms, and diseases 显示文摘MACDONALD B T TAMAI K HE X 2009Dev Cell2009,17,1:1
11Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treat ment for drug-resistant hypertension (PATHWAY-2) : a random- ised, double-blind, crossover trial显示文摘Williams B MacDonald T Morant S 2015Lancet2015,386,10008:1
12Al ion in Biological systems显示文摘MacDonald T Martin R B 1998Trends in Biological Science1998,13,:1
13An STM study of the effects of the ion incident angle and energy on surface damage induced by Ar^+ bombardment of HOPG显示文摘Li T King B V MacDonald R J 1994Surf Sci1994,312,3:1
14Myocardial bridging in children with hypertrophic cardiomyopathy: a risk factor for sudden death显示文摘Yetman A T McCrindle B W MacDonald C 1998N Engl J Med1998,339,17:1
15Bone mass is inversely proportional to Dkkl levcls in mice显示文摘MacDonald B T Joiner D M Oyserman S M 0,,03:1
16Frizzled and LRP5/6 receptors for Wnt/ beta-catenin signaling显示文摘Macdonald B T He X 2012Cold Spring Harb Perspect Biol2012,4,12:1
17SnapShot:noncano-nical Wnt signaling pathways显示文摘Semenov M V Habas R MacDonald B T 2007Cell2007,131,7:1
18Wnt//3-catenin signaling: components, mechanisms, and diseases 显示文摘MacDONALD B T TAMAI K HE X 2009Dev Cell2009,17,1:1
19Wnt/beta-catenin signaling:com- ponents,mechanisms,and diseases显示文摘Macdonald B T Tamai K He X 2009Dev Cell2009,17,1:1
20Spironolaetone versus placebo, bisoprolol, and doxazosin to determine the optimal treat- ment for drug-resistant hypertension (PATHWAY-2) : a random- ised, double-blind, crossover trial显示文摘Williams B MacDonald T Morant S 2015Lancet2015,386,10008:1
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