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67篇 您的检索式:作者名="Madjd"
    题名 作者 年代 出处 被引量
1Cytoplasmic expression of p27^(kip1) is associated with a favourable prognosis in colorectal cancer patients显示文摘AIM: To evaluate the prognostic significance of p27kip1 in colorectal cancer patients. METHODS: Cytoplasmic and nuclear p27kip1 expression was evaluated in 418 colorectal cancers using tissue microarrays. Data were associated with known patient and tumor variables and long-term patient outcomes, providing further insight into the mechanisms by which p27kip1 may influence tumor development. RESULTS: Nuclear and cytoplasmic p27Kip1 expressions were detected in 59% and 19% of tumors respectively. Cytoplasmic p27Kip1 was almost invariably associated with positive nuclear p27Kip1 expression. Neither case correlat- ed with known clinical or pathological variables, includ- ing tumor stage, grade or extramural vascular invasion. Furthermore, nuclear p27kip1 expression had no impact on survival. However, we identified a significant correla- tion between expression of cytoplasmic p27kip1 and longer disease-specific survival times. On multivariate analysis, TNM stage and extramural vascular invasion were highly significant independent prognostic factors, with positive cytoplasmic p27 expression showing a trend towards im- proved patient survival (P = 0.059).CONCLUSION: These findings support the recent evi- dence that cytoplasmic p27kip1 has a distinct and impor- tant biological role that can influence tumor outcome.Nicholas FS Watson Lindy G Durrant John H Scholefield Zahra Madjd Duncan Scrimgeour Ian Spendlove Ian O Ellis Poulam M Patel 2006World Journal of Gastroenterology2006,12,39:3
2Expression of thestress-related MHC class I chain-related protein MICA is anindicator of good prognosis in colorectal cancer patients显示文摘Watson NF Spendlove I Madjd Z 2006Int JCancer2006,118,14:1
3Expression of the stressrelated MHC class Ⅰ chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients显示文摘Watson N Spendlove I Madjd Z 2006Int J Cancer2006,118,:1
4CD44^+ cancer cells express higher levels of the anti-apoptotic protein Bcl- 2 in breast turnouts 显示文摘Madjd Z Mehrjerdi AZ Sharifi AM 2009Cancer Immun2009,23,9:1
5Expression of the stress-related MHC class Ⅰ chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients 显示文摘WATSON N F SPENDLOVE I MADJD Z 2006Int J Cancer2006,118,6:1
6The p53 positive Bcl-2 negative phenotype is an independent marker of prognosis in breast cancer显示文摘Rolland P Spendlove I Madjd Z 2007Int J Caneer2007,120,6:1
7CD44+ cancer cells ex press higher levels of the anti-apoptotic protein Bcl-2 in breast tumours显示文摘Madjd Z Mehrjerdi AZ Sharifi AM 2009Cancer Immun2009,9,:1
8The selective neurotoxicity produced by 3-chloropropanediol in the rat is not a result of energy deprivation显示文摘J. Skamarauskas W. Carter M. Fowler A. Madjd T. Lister G. Mavroudis D.E. Ray 2007Toxicology2007,,3:1
9Immunosurveillance is active in colonrectal cancer as downregulation but not complete loss of MHC class Ⅰ expreesion correlates with a poor prognosis 显示文摘Watson Nf Ramage JM Madjd Z 2006Int J Cancer2006,118,:1
10CD44~ cancercells express higher levels of the anti -apoptotic proteinBcl-2 in breast tumours 显示文摘Madjd Z Mehrjerdi AZ Sharifi AM 2009Cancer Immun2009,9,:1
11Expression of the stress- related MHC class 1 chain-related protein MICA is an indcator of good prognosis in colorectal cancer patients 显示文摘Watson NF Spendlove I Madjd Z 2006Int J Cancer2006,118,6:1
12Do poor-prognosis breast tumours express membrane cofactor proteins (CD46)? 显示文摘Madjd Z 2005Cancer Immunol Immunother2005,54,2:1
13Expression of the stress-related MHC class I chain--related protein MICA is an indi- cator of good prognosis in colorectal cancer patients显示文摘Watson NF Spendlove I Madjd Z 2006IntJ Can- cer2006,118,6:1
14High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas 显示文摘Madjd Z Ramezani B Molanae S 2012Asian Pac J Cancer Prey2012,13,6:1
15Expression of the stress-related MHC class I chaln-related protein MICA is an indicator of good prognosis in colorectal cancer patients 显示文摘Watson NF Spendlove I Madjd Z McGilvray R Green AR Ellis IO 2006Int J Cancer2006,118,6:1
16Loss of CD55 is associated with aggressive breast tumors显示文摘Madjd Z Durrant LG Bradley R etal 2004Clin Cancer Res2004,10,8:1
17CD44 + cancer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours显示文摘Madjd Z Mehrjerdi AZ Sharifi AM 2009Cancer Immun2009,9,:1
18CD44+ cancer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours 显示文摘Madjd Z Mehrjerdi A Z Sharifi A M 2009Cancer Imrnun2009,23,9:1
19Upregulation of MICA on high-grade invasive operable breast carcinoma 显示文摘Madjd Z Spendlove I Moss R 2007Cancer Immun2007,7,6:1
20High expression of Lewisy/b antigens is associated with decreased survival in lymph node negative breast carcinomas显示文摘 Parsons T Watson NFS 2005Breast Cancer Res2005,7,5:1
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