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| 1 | A novel and efficient synthesis of pyrazolo[3,4-d]pyrimidine derivatives and the study of their anti-bacterial activity显示文摘In this work 4-amino-6-aryl-2-phenyl pyrimidine-5-carbonitrile derivatives were synthesized through a one-pot,three-component reaction of an aldehyde,malononitrile and benzamidine hydrochloride,in the presence of magnetic nano Fe_3O_4 particles as a catalyst under solvent-free conditions.3-Amino-6-aryl- 2-phenylpyrazolo[3,4-d]pyrimidine derivatives were prepared through an efficient and environmentally friendly reaction between 4-amino-6-aryl-2-phenylpyrimidine-5-carbonitrile derivatives and hydrazine hydrate and their antibacterial activity has been evaluated. | Shahnaz Rostamizadeh Masoomeh Nojavan Reza Aryan Hamid Sadeghian Mahdieh Davoodnejad | 2013 | Chinese Chemical Letters2013，24，7： | 7 |
| 2 | Selective and mild oxidation of sulfides to sulfoxides by H_2O_2 using DBUH-Br_3 as catalyst显示文摘DBUH-Br3 catalyzed selective conversion of sulfides to sulfoxides in the presence of H2O2 as oxidizing agent is described. The reaction was performed selectively at room temperature and relatively short reaction times. | Mehdi Bakavoli Alireza Motavalizadeh Kakhky Ali Shiri Mahdieh Ghabdian Abolghasem Davoodnia Hossein Eshghi Mola Khatami | 2010 | Chinese Chemical Letters2010，21，6： | 3 |
| 3 | Mapping alteration minerals using sub-pixel unmixing of ASTER data in the Sarduiyeh area,SE Kerman,Iran显示文摘This paper is an attempt to introduce the role of earth observation technology and a type of digital earth processing in mineral resources exploration and assessment.The sub-pixel distribution and quantity of alteration minerals were mapped using linear spectral unmixing(LSU)and mixture tuned matched filtering(MTMF)algorithms in the Sarduiyeh area,SE Kerman,Iran,using the visible-near infrared(VNIR)and short wave infrared(SWIR)bands of the Advanced Spaceborne Thermal Emission and Reflection Radiometer(ASTER)instrument and the results were compared to evaluate the efficiency of methods.Three groups of alteration minerals were identified:(1)pyrophylite-alunite(2)sericite-kaolinite,and(3)chlorite-calcite-epidote.Results showed that high abundances within pixels were successfully corresponded to the alteration zones.In addition,a number of unreported altered areas were identified.Field observations and X-ray diffraction(XRD)analysis of field samples confirmed the dominant mineral phases identified remotely.Results of LSU and MTMF were generally similar with overall accuracy of 82.9 and 90.24%,respectively.It is concluded that LSU and MTMF are suitable for sub-pixel mapping of alteration minerals and when the purpose is identification of particular targets,rather than all the elements in the scene,the MTMF algorithm could be proposed. | Mahdieh Hosseinjani Majid H.Tangestani | 2011 | International Journal of Digital Earth2011，4，6： | 3 |
| 4 | 甲烷气体还原锰矿和水热沉淀法制备纳米MnO_2(英文)显示文摘采用甲烷气体还原锰矿、溶解和水热沉淀方法制备MnO2纳米棒。甲烷气体还原反应在850、875、900、925和950℃下进行120min,生成α-MnO2纳米棒的沉淀反应在25~90℃下进行90min。采用SEM和X射线衍射对制备的产物形貌和颗粒尺寸进行表征。采用比表面分析仪测定产物的BET和BJH值。结果表明,在反应温度950℃下,MnO相大量生成,而MnO2相消失。所制备的α-MnO2纳米棒的平均直径约为50mm,其BET比表面积为174m2/g。 | Davood MORADKHANI Mahdieh M ALEKZADEH Eltefat AHMADI | 2013 | Transactions of Nonferrous Metals Society of China2013，23，1： | 2 |
| 5 | Effects of vernacular architecture structure on urban sustainability case study: Qeshm Island, Iran显示文摘 | Hamed Mohammadi Mazraeh Mahdieh Pazhouhanfar | 2018 | Frontiers of Architectural Research2018，7，1： | 2 |
| 6 | Automatically Eye Detection with Different Gray Intensity Image Conditions显示文摘 | Mitra Montazeri Hossein Nezamabadi-pour Mahdieh Montazeri | 2012 | Computer Technology and Application2012，3，8： | 2 |
| 7 | Mechanisms of disease: The oxidative stress theory of diabetic neuropathy显示文摘 | Claudia Figueroa-Romero Mahdieh Sadidi Eva L. Feldman | 2008 | Reviews in Endocrine and Metabolic Disorders2008，，4： | 2 |
| 8 | Drought stress alters water relations and expression of PIP-type aquaporin genes in Nicotiana tabacum plants显示文摘 | Mahdieh M Mostajeran A Horie T | 2008 | Plant Cell Physiol2008，49，5： | 1 |
| 9 | Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disorders显示文摘 | Rabbani B Mahdieh N Hosomichi K | 2012 | J Hum Genet2012，57，10： | 1 |
| 10 | ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation显示文摘A disintegrin and metalloproteinase(ADAM)12 was previously found to be expressed in T cells in the inflamed brain.However,the function of ADAM12 in T-cell responses in general and in tissue inflammation has not been examined.Here,we studied the role of ADAM12 in T-cell responses,fate determination on activation,and its functions in T cells to mediate tissue inflammation.We identified ADAM12 as a costimulatory molecule that is expressed on naive T cells and downregulated on stimulation.ADAM12 mimics CD28 costimulatory signaling to activate and induce the proliferation of T-helper 1(Th1)cells.Monoclonal ADAM12 Fab antibodies trigger T-cell activation by amplifying TCR signaling to stimulate T-bet-mediated IFNγproduction.Lack of genomic ADAM12 and its knockdown in T cells diminished T-bet and IFNγproduction in Th1 cells,whereas other T cells,including Th17 cells,were unaffected.ADAM12 had similar functions in vivo on myelin antigen(MOG_(35-55))-induced T-cell activation.We found that genetic loss of ADAM12 profoundly alleviated Th1-mediated neuroinflammation and thus disease severity in experimental autoimmune encephalomyelitis,a model of multiple sclerosis.Transcriptomic profiling of MOG_(35-55)-specific ADAM12^(−/−)T cells revealed differentially expressed genes that are important for T-cell activation,proliferation,and costimulatory signaling and Th1 pathogenicity,consistent with their inability to cause T-cell-mediated skin inflammation in a model of adoptive delayed-type hypersensitivity.We conclude that ADAM12 is a T-cell costimulatory molecule that contributes to the pathogenesis of tissue inflammation and a potential target for the treatment of Th1-mediated diseases. | Yawei Liu Robert Bockermann Mahdieh Hadi Iman Safari Belinda Carrion Marie Kveiborg Shohreh Issazadeh-Navikas | 2021 | Cellular & Molecular Immunology2021，18，8： | 1 |
| 11 | Kernel-based metric learning for se- mi-supervised clustering显示文摘 | Mahdieh S B Saeed B S | 2010 | Neurocomputing2010，73，79： | 1 |
| 12 | Mutation analysis of the CYP21A2 gene in the Iranian population显示文摘 | Rabbani B Mahdieh N Ashtiani MT | 2012 | Genet Test Mol Biomarkers2012，16，： | 1 |
| 13 | Non-linear Metric Learning Using Pairwise Similarity and Dissimilarity Constraints and the Geometrical Structure of Data显示文摘 | Mahdieh S B Saeed B S | 2010 | Pattern Recognition2010，43，8： | 1 |
| 14 | Trend of laser research developments in global level显示文摘 | Golnabi H Mahdieh M H | 2006 | Optics and Laser Technology2006，38，2： | 1 |
| 15 | Two-dimensional-simulation of therrml blooming effects in ring pattem laser beams显示文摘 | Mahdieh M H Lotfi B | 2005 | Optical Engineering2005，44，09： | 1 |
| 16 | Mental Health Status in Patients with Tha-lassemia Major in Iran显示文摘 | Mahdieh Nasiri Seyed Hamzeh Hosseini Soheila Shah-mohammadi | 2014 | J Pediatr Rev2014，2，1： | 1 |
| 17 | Strong convergence of split-step backward Euler methodfor stochastic differential equations with nonsmooth drift显示文摘 | Ali Foroush Bastani Mahdieh Tahmasebi | 2012 | Journal of Computational and Applied Mathematics2012，236，7： | 1 |
| 18 | Drought stress alters water relations and expression of PIP-type aquaporin genes in Nicotiana tabacum plants 显示文摘 | Mahdieh M N Horie T Katsuhara M | 2008 | Plant & Cell Physiology2008，49，： | 1 |
| 19 | Production of silver nanoparticles by electromagnetic levitation gas condensation显示文摘 | Mahdieh Malekzadeh Mohammad Halali | 2011 | Chemical Engineering Journal2011，，1： | 1 |
| 20 | 3-Dimensional simulation and footprint of optical breakdown in dielectrics induced by femtosecond laser pulse显示文摘 | M.H. Mahdieh M. Gharibzadeh | 2012 | Optics and Laser Technology2012，，6： | 1 |
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