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| 1 | Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption显示文摘AIM:To establish the prevalence of Helicobacter pylori (H. pylori ) infection in patients with a bleeding peptic ulcer after consumption of non-steroidal antiinflamma- tory drugs (NSAIDs). METHODS:A very early upper endoscopy was performed to find the source of upper gastrointestinal bleeding and to take biopsy specimens for analysis of H. pylori infection by the rapid urease (CLO) test, histological examination, and bacterial culture. IgG anti-CagA were also sought. The gold standard for identifying H. pylori infection was positive culture of biopsy specimens or contemporary positivity of the CLO test and the presence of H. pylori on tissue sections. RESULTS:Eighty patients, 61 males (76.3%), mean age 61.2 ± 15.9 years, were consecutively enrolled. Forty-seven (58.8%) patients occasionally consumed NSAIDs, while 33 (41.3%) were on chronic treatment with low-dose aspirin (LD ASA). Forty-four (55.0%) patients were considered infected by H. pylori . The infection rate was not different between patients who occasionally or chronically consumed NSAIDs. The culture of biopsy specimens had a sensitivity of 86.4% and a specificity of 100%; corresponding figures for histological analysis were 65.9% and 77.8%, for the CLO test were 68.2% and 75%, for the combined use of histology and the CLO test were 56.8% and 100%, and for IgG anti-CagA were 90% and 98%. The highest accuracy (92.5%) was obtained with the culture of biopsy specimens.CONCLUSION:Patients with a bleeding peptic ulcer after NSAID/LD ASA consumption frequently have H. pylori infection. Biopsy specimen culture after an early upper gastrointestinal tract endoscopy seems the most efficient test to detect this infection. | Francesco Manguso Elisabetta Riccio Germana de Nucci Maria Luisa Aiezza Gerardino Amato Linda Degl'Innocenti Maria Maddalena Piccirillo Gianfranco De Dominicis Tara Santoro Elena Trimarco Antonio Balzano | 2011 | World Journal of Gastroenterology2011,17,40: | 4 |
| 2 | Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis显示文摘 | Lucio Amitrano Maria Anna Guardascione Vincenzo Brancaccio Maurizio Margaglione Francesco Manguso Luigi Iannaccone Elvira Grandone Antonio Balzano | 2004 | Journal of Hepatology2004,,5: | 2 |
| 3 | Pulmonary Vein Denervation Enhances Long-Term Benefit After Circumferential Ablation for Paroxysmal Atrial Fibrillation显示文摘 | Carlo Pappone Vincenzo Santinelli Francesco Manguso Gabriele Vicedomini Filippo Gugliotta Giuseppe Augello Patrizio Mazzone Valter Tortoriello Giovanni Landoni Alberto Zangrillo Christopher Lang Takeshi Tomita Cézar Mesas Elio Mastella Ottavio Alfieri | 2004 | Circulation: Journal of the American Heart Association2004,,3: | 2 |
| 4 | Diagnostic value of faecal calprotectin in paediatric gastroenterology clinical practice显示文摘 | R. Berni Canani L. Rapacciuolo M.T. Romano L. Tanturri de Horatio G. Terrin F. Manguso P. Cirillo F. Paparo R. Troncone | 2004 | Digestive and Liver Disease2004,,7: | 1 |
| 5 | Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation显示文摘 | Pappone C Santinelli V Manguso F | 2004 | Circulation2004,109,: | 1 |
| 6 | Risk of malignant arrhythmias in initially symptomatic patients with Wolff-Parkinson-White syndrome:results of a prospective long-term electrophysiological follow-up study显示文摘 | Pappone C Vicedomini G Manguso F | | 0,,05: | 1 |
| 7 | Prevemion of iatrogenic atrial tachycardia after ablation of atrial fibrillation: a prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach显示文摘 | Pappone C Manguso F Vicedomini G | 2004 | Circulation2004,110,19: | 1 |
| 8 | Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation显示文摘 | Pappone C Santinelli V Manguso F | 2004 | Circulation2004,109,3: | 1 |
| 9 | Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation显示文摘 | PAPPONE C SANTINELLI V MANGUSO F | 2004 | Circulation2004,109,3: | 1 |
| 10 | Serum calprotectin: an an- timicrobial peptide as a new marker for the diagnosis of sepsis in very low birth weizht newborns 显示文摘 | Terrin G PassarielIo A Manguso F | 2011 | Clin Dev Immunol2011,,: | 1 |
| 11 | Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation显示文摘 | Pappone C Santinelli V Manguso F | 2004 | Circulation2004,109,: | 1 |
| 12 | Prognostic Value of Progressive Decrease in Serum Cholesterol in Predicting Survival in Child-pugh C Viralcirrhosis显示文摘 | D'Arienzo A Manguso F Scaglione G | 1998 | Scand J Gastroenterol1998,33,11: | 1 |
| 13 | Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation 显示文摘 | Pappone C Santinelli V Manguso F | 2004 | Circulation2004,109,3: | 1 |
| 14 | Robotic magnetic navigation for atrial fibrillation ablation 显示文摘 | Pappone C Vicedomini G Manguso F | 2006 | Am Coil Cardiol2006,47,7: | 1 |
| 15 | Prevention of iatrogenic atrial tachycardia after ablation of atrial fibrillation:a prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach 显示文摘 | Pappone C Manguso F Vicedomini G | 2004 | Circulation2004,110,19: | 1 |
| 16 | Prevention of iatrogenic atrial tachycardia after ablation of atrial fibrillation:a prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach显示文摘 | Pappone C Manguso F Vicedomini G | 2004 | Circulation2004,110,19: | 1 |
| 17 | Effects of an appropriate oral diet on the nutritional status of patients with HCV-related liver cirrhosis:a prospective study显示文摘 | Manguso F D’Ambra G Menchise A | 2005 | Clin Nutr2005,24,5: | 1 |
| 18 | Pulmonary vein denerration enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation 显示文摘 | Pappone C Santinelli V Manguso F | 2004 | Circulation2004,109,3: | 1 |
| 19 | Asymptomatic ventricular preexcitation:a long-term prospective follow-up study of 293 adult patients显示文摘 | Santinelli V Radinovic A Manguso F | | 0,,02: | 1 |
| 20 | Electrochemiluminescence immunoassay method underestimates cortisol suppression in ulcerative colitis patients treated with oral prednisone显示文摘AIM: To evaluate cortisolemia by using conventional electrochemiluminescence immunoassay(ECLIA) method compared to liquid chromatography-tandem mass spectrometry(LC-MS/MS) method in active ulcerative colitis(UC) patients treated with oral prednisone(PD). METHODS: Twenty patients(12 males) with acute relapse of UC started oral PD at a dose of 40 mg once a day, tapered of 10 mg every 2 wk. When a stable 2-wk daily dose of 30 mg was reached, blood samples for cortisol levels' measurement were drawn in the morning in fasting conditions to determine circulating cortisol by LC-MS/MS and ECLIA assay. RESULTS: Median interquartile range cortisolemia with ECLIA and LC-MS/MS method was 54.1(185.8) nmol/L and 32.1(124.0) nmol/L, respectively(P < 0.001). The within-patient median differences between the two methods was 23.2(40.6) nmol/L, with higher cortisol levels for the ECLIA method. The estimated geomet-ric mean ratio between methods was 1.85(95%CI: 2.39-1.43) considering all data or 1.58(95%CI: 2.30-1.09) considering only data above the limit of quantification(n = 12). The 95%CIs of the geometric mean ratio between methods confirm a statistically significant difference.CONCLUSION: Blood cortisol levels detected with ECLIA method seems to be higher than the ones measured by LC-MS/MS, indicating a possible overestimation of them in patients treated with PD. Therefore, the cortisol suppression in patients under treatment with oral PD should not be measured using ECLIA method. | Francesco Manguso Raffaele Bennato Giovanni Lombardi Assunta Viola Elisabetta Riccio Livio Cipolletta | 2014 | World Journal of Gastroenterology2014,20,31: | 1 |