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| 1 | Comparison of TiAlN, AlCrN, and AlCrN/TiAlN coatings for cutting-tool applications显示文摘Monolayer and bilayer coatings of TiAlN, AlCrN, and AlCrN/TiAlN were deposited onto tungsten carbide inserts using the plasma enhanced physical vapor deposition process. The microstructures of the coatings were characterized using scanning electron microscopy(SEM) and atomic force microscopy(AFM). The SEM micrographs revealed that the AlCrN and AlCrN/TiAlN coatings were uniform and highly dense and contained only a limited number of microvoids. The TiAlN coating was non-uniform and highly porous and contained more micro droplets. The hardness and scratch resistance of the specimens were measured using a nanoindentation tester and scratch tester, respectively. Different phases formed in the coatings were analyzed by X-ray diffraction(XRD). The AlCrN/TiAlN coating exhibited a higher hardness(32.75 GPa), a higher Young's modulus(561.97 GPa), and superior scratch resistance(LCN = 46 N) compared to conventional coatings such as TiAlN, AlCrN, and TiN. | T.Sampath Kumar S.Balasivanandha Prabu Geetha Manivasagam K.A.Padmanabhan | 2014 | International Journal of Minerals,Metallurgy and Materials2014,21,8: | 8 |
| 2 | Hepatoprotective activity of brown alga Padina boergesenii against CCl_4 induced oxidative damage in Wistar rats显示文摘Objective:To investigate the protective effects of brown alga Padina boergesenii(P.boergeseii) against carbon tetrachloride(CCl4) induced oxidative damage and liver fibrosis in rats.Methods: To assess the hepatic damage liver weight,the activities of TBARS level,glutathione,SOD,CAT and GPx in circulation and liver.Results:The group of rats induced with CCl4 alone(2 mL/kg body weight),showed noticeable increase in the liver weight and TBARS level.Followed by, the level of antioxidant enzymes glutathione peroxidase,Superoxide dismutase and catalase was also significantly(P<0.01) diminished.Where as,the rats pretreated with P.boergesenii(150 mg/ kg body weight) modulated the CCl4 induced liver fibrosis.The level of antioxidant enzymes and lipid peroxidation products was found to be significandy(P<0.01) attenuated to near normal level, when compared with rats induced with CCL,alone.In order to assess the role of carotenoids in the relevant activity,total carotenoid content of the extract was analysed and found to be 0.59 mg/g fresh weight(FW).Further,the histopathogical studies provide a supportive evidence for this study to show the protective nature of P.boergesenii.Conclusions:The protective role of brown alga P.boergesenii extract has confirmed its potential activity through its antioxidant sparing actions against CCl4 induced free radical damage.However,the possible mechanism of hepatoprotection is rather speculative at this stage and investigations are underway to isolate and characterize the bioactive compounds from P.boergesenii. | Rajamani Karthikeyan ST Somasundaram T Manivasagam T Balasubramanian P Anantharaman | 2010 | Asian Pacific Journal of Tropical Medicine2010,3,9: | 6 |
| 3 | Neuroprotective effects of berry fruits on neurodegenerative diseases显示文摘Recent clinical research has demonstrated that berry fruits can prevent age-related neurodegenerative diseases and improve motor and cognitive functions. The berry fruits are also capable of modulating signaling pathways involved in inflammation, cell survival, neurotransmission and enhancing neuroplasticity. The neuroprotective effects of berry fruits on neurodegenerative diseases are related to phytochemicals such as anthocyanin, caffeic acid, catechin, quercetin, kaempferol and tannin. In this review, we made an attempt to clearly describe the beneficial effects of various types of berries as promising neuroprotective agents. | Selvaraju Subash Musthafa Mohamed Essa Samir Al-Adawi Mushtaq A.Memon Thamilarasan Manivasagam Mohammed Akbar | 2014 | Neural Regeneration Research2014,9,16: | 3 |
| 4 | Therapeutic Attenuation of Neuroinflammation and Apoptosis by Black Tea Theaflavin in Chronic MPTP/Probenecid Model of Parkinson’s Disease显示文摘 | Annadurai Anandhan Musthafa Mohamed Essa Thamilarasan Manivasagam | 2013 | Neurotoxicity Research2013,,2: | 2 |
| 5 | Bacterial adherence and biofilm formation on medical implants: a review 显示文摘 | Veerachamy S Yarlagadda T Manivasagam G | 2014 | Proe Inst Mech Eng H2014,228,10: | 1 |
| 6 | Therapeutic Attenuation of Neuroinflammation and Apoptosis by Black Tea Theaflavin in Chronic MPTP/Probenecid Model of Parkinson's Disease显示文摘 | Anandhan A Essa M M Manivasagam T | 2013 | Ncurotox Res2013,23,2: | 1 |
| 7 | Circadian rhyth- micity of plasma lipid peroxidation and antioxidants in oral squa- mous cell carcinoma显示文摘 | Manoharan S Baskar AA Manivasagam T | 2005 | Singapore Med J2005,46,4: | 1 |
| 8 | Multimodal physical therapy management of a 48-year-old female with post-stroke complex regional pain syndrome显示文摘 | Anandkumar S Manivasagam M | 2014 | Physiother Theory Pract2014,30,1: | 1 |
| 9 | Multimodal physical thera- py management of a 48-year-old female with post-stroke com- plex regional pain syndrome 显示文摘 | Anandkumar S Manivasagam M | 2014 | Physiother Theory Pract2014,30,1: | 1 |
| 10 | Chemo- preventive effect of padina boergesenii extracts on ferric nitrilori- acetate (Fe-NTA) induced oxidative damage in Wistar rats显示文摘 | Karthikeyan R Manivasagam T Anantharaman P | 2011 | J Appl Phycol2011,23,2: | 1 |
| 11 | Effect of texture and grain size on bio-corrosion response of ultrafine-grained titanium 显示文摘 | Gurao N P Manivasagam G Govindaraj P | 2013 | Metallurgical and Materials Transactions A2013,44,12: | 1 |
| 12 | Elevated epidermal thymic stromal lymphopoietinlevels establish an antitumor environment in the skin显示文摘 | DEMEHRI S TURKOZ A MANIVASAGAM S etal | 2012 | Cancer Cell ?2012,22,: | 1 |
| 13 | Mangiferin antagonizes rotenone: Induced apoptosis through attenuating mitochondrial dysfunction and oxi- dative stress in SK-N-SH neuroblastoma cells 显示文摘 | KAVITHAM MANIVASAGAM T ESSA M M | 2014 | Neurochemical Research2014,39,4: | 1 |
| 14 | Elastic load-displacement predictions for coned disc spring subieeted to axial load- ing using the finite element method显示文摘 | BAGAVATHIPERUMAL P CHANDRASEKARAN K MANIVASAGAM S | 1991 | Journal of Strain Analysis for Engineering Design1991,26,2: | 1 |
| 15 | Elastic load-displacement predictions for coned disc springs subjected to axial loading using the finite element method显示文摘 | Bagavathiperumal P Chandrasekaran K Manivasagam S | 1991 | Journal of Strain Analysis for Engineering Design1991,26,3: | 1 |
| 16 | Effect of Nano Oil Additive Proportions on Frictin and Wear Performance of Automotive Materials显示文摘 | Vadiraj A Manivasagam G Kamani K | 2012 | Tribology in Industry2012,34,1: | 1 |
| 17 | Mangiferin antagonizes rotenone: induced apoptosis through attenuating mitochondrial dysfunction and oxidative stress in SK-N-SH neuroblastoma cells显示文摘 | Kavitha M Manivasagam T Essa M M | 2014 | Neurochem Res2014,39,4: | 1 |
| 18 | A framework for the sustainability implications of 3D bioprinting through nature-inspired materials and structures显示文摘Introduction The climax of the industrial revolution was marked by the rapid growth of industry,and advancement in technologies have further fueled this industrial expansion,leading to a surge in economic growth.However.these technologies have also increased the degree of destructive human inter-ference with the biosphere. | Ruban Whenish Seeram Ramakrishna Amit Kumar Jaiswal Geetha Manivasagam | 2022 | Bio-Design and Manufacturing2022,5,2: | 0 |