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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | Medication-related Problems in Ambulatory Hemodialysis Patients:a Pooled Analysis显示文摘 | Manley H J Cannella C A Bailie G R | 2005 | Am J Kidney Dis2005，46，4： | 1 |
| 3 | An Analysis of RadiM Segregation for Different Sized Spherical Solids in Rotary Cylinders 显示文摘 | Nityanand N Manley B Henein H | 1986 | Metallurgical Transactions B1986，17，2： | 1 |
| 4 | Ontology-based assembly design and information sharing for collaborative product development显示文摘 | KIM K Y MANLEY D G YANG H | 2006 | Computer- Aided Design2006，38，12： | 1 |
| 5 | Medication-related problems in ambulatory hemodialysis patients, a pooled analysis显示文摘 | Manley H J Cannella CA Bailie GR | 2005 | Am J Kidney Dis2005，46，4： | 1 |
| 6 | Project Partnering: A Medium for Private and Public Sector Collaboration 显示文摘 | T Roger Manley Wade H Shaw Robert C Manley | 2007 | Engineering Management Journal2007，19，20： | 1 |
| 7 | Ontology-based assembly design and information sharing for collaborative product development 显示文摘 | Kim K Manley D Yang H | 2006 | Computer- Aided Design2006，38，12： | 1 |
| 8 | Sevenfold- reduced osmotic water permeability in primary astrocyte cultures from AQP 4-deficient mice, measured by a fluorescence quenching method 显示文摘 | Solenov E Watanabe H Manley GT | 2004 | Arn J Physiol Cell Physiol2004，286，2： | 1 |
| 9 | Sevenfoldreduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice,measured by a fluoreseenee quenching method显示文摘 | Solenov E Watanabe H Manley GT | 2004 | Physiol Cell Physio12004，286，： | 1 |
| 10 | The Emerging Role of Autophagy in Alcoholic Liver Disease显示文摘 | Ding W X Manley S Ni H M | 2011 | Exp Biol Med(Maywood)2011，236，5： | 1 |
| 11 | Ontology based assembly design and information sharing for collaborative product development 显示文摘 | Kim K Y Manley D G Yang H | 2006 | Computer-Aided Design2006，38，12： | 1 |
| 12 | Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method显示文摘 | Solenov E Watanabe H Manley GT | 2004 | Am J Physiol Cell Physiol2004，286，2： | 1 |
| 13 | Formation of pyrazolines from unsymmetrically substituted dibenzalacetones显示文摘 | RAIFORD L C MANLEY R H | | 0，，6： | 1 |
| 14 | The emerging role of autophagy in alcoholic liver disease显示文摘 | Ding W Manley S Ni H | | 0，，： | 1 |
| 15 | Ontology-based assembly design and information sharing for collaborative product development显示文摘 | KIM K Y MANLEY D G YANG H J | 2006 | Computer-Aided Design2006，38，12： | 1 |
| 16 | Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice,measured by a fluorescencequenching method显示文摘 | Solenov E Watanabe H Manley GT | 2004 | Am J Physiol Cell Physiol2004，286，2： | 1 |
| 17 | PhotoactivatablemCherry for high-resolution two-color fluorescence micros-copy显示文摘 | Subach F V Patterson G H Manley S Gillette J M Lip-pincott-Schwartz J Verkhusha V V | 2009 | Nature Methods2009，6，2： | 1 |
| 18 | Ontology-based assembly design and information sharing for collaborative product development显示文摘 | Kim K Manley D Yang H | 2006 | Computer-Aided Design2006，38，： | 1 |
| 19 | Hyperglycemia and hyperinsulinemia at diagnosis of diabetes and their association with subsequent cardiovascular disease in the United Kingdom prospective diabetes study (UKPDS 47) 显示文摘 | Adler A I Neil H A Manley S E | 1999 | Am Heart J1999，138，51： | 1 |
| 20 | Ontology-based Assembly Design and Information Sharing for Collaborative Product Development 显示文摘 | Kim K Y Manley D G Yang H | 2006 | Computer-Aided Design2006，38，12： | 1 |
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