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| 1 | 围手术期患者的安全:正确的患者、正确的手术、正确的部位——一项多因素、跨部门的干预性研究显示文摘背景为围手术期患者提供安全的环境非常重要。基于这一点,我们在围手术期实施了“患者安全第一”的政策。方法在干预性研究的第一阶段(2001—2002年),我们首先制定并实施干预性研究中组织和教育方面的内容。2003至2005年为研究的实施阶段。根据我们的零忍受原则,在手术等候区内一旦发现患者的麻醉或手术准备工作中有重大差错,该患者就被送回病房(失败),并等到差错得到纠正后再进行手术。结果共有15856例患者参加了研究。在研究实施阶段的3年中,有112例患者被送回病房(0.71%)。与2003年的数据相比,2004年和2005年发生的重大错误明显减少,且有统计学意义(2003、2004和2005年的数据分别为1.04%、0.59%和0.49%)。而且,逐步逻辑回归方法分析结果显示,手术前准备不充分所致重大错误的发生率逐年下降,具有统计学意义(比值比=1.48,95%CI:1.16~1.87)。此外,在2003、2004和2005年中,各年的失败发生平均间隔时间分别为6.6、11.2和14.7天(P〈0.03)。最后,不仅患者手术前准备工作在研究期间有显著改善(P〈0.0001);而且,使患者手术前准备工作评分为100%的可能性也有明显增加(P〈0.001)。结论教育和提高认识能减少围手术期的错误发生率。但是,即使有详细规划的制度,也无法达到无差错的环境。因此,检查和全面分析应该持续不断地进行。 | Edna Zohar Yossi Noga Ehud Davidson Margalit Kantor Brian Fredman 周全红(译) 江伟(校) | 2008 | 麻醉与镇痛2008,4,4: | 5 |
| 2 | Mediterranean dietary components are inversely associated with advanced colorectal polyps:A case-control study显示文摘AIM To evaluate the association between the Mediterranean diet(MD) pattern and its components, and advanced colorectal polyps(adenoma and serrated adenoma).METHODS A case-control study among patients undergoing screening, diagnostic or surveillance colonoscopies during 2010-2015 at the Tel-Aviv Medical Center, Gastroenterology Department. Cases with advanced polyps were defined as: Advanced adenoma [> 10 mm, with features of high grade dysplasia(HGD) or villous histology], advanced serrated adenoma(> 10 mm or with dysplasia) or multiple(≥ 3) non-advanced adenomas or serrated adenomas. Cases of non-advanced adenomas were defined as adenomas < 10 mm, without features of HGD or villous histology. Controls were defined as those without polyps at the current colonoscopy and without a history of colorectal polyps. Data collection included: anthropometrics measured according to a standardized protocol, fasting blood tests performed at the same lab, medical history recorded by a structured interview and dietary intake evaluated by a 116-item food frequency questionnaire. Adherence to the MD components was evaluated according to intake above/below the sample median, for potentially beneficial/detrimental components respectively, as accepted. RESULTS We recruited 206 cases with advanced polyps, 192 cases with non-advanced adenoma and 385 controls. The number of adhered MD components was inversely associated with a diagnosis of advanced polyps in a dose-response manner(OR = 0.34, 95%CI: 0.17-0.65; OR = 0.22, 95%CI: 0.11-0.43; and OR = 0.18, 95%CI: 0.07-0.47 for 3-4, 5-7 and 8-10 components, respectively), but not with non-advanced adenomas(OR = 0.54, 95%CI: 0.25-1.13; OR = 0.48, 95%CI: 0.23-0.99; and OR = 0.43, 95%CI: 0.16-1.12 for 3-4, 5-7 and 8-10 components, respectively). Low intake of sugar-sweetened beverages and red meat, as well as high intake of fish, were inversely associated with advanced polyps(OR = 0.56, 95%CI: 0.36-0.87; OR = 0.63, 95%CI: 0.42-0.95; and OR = 0.66, 95%CI: 0.44-0.99, respectively), while only low intake of red meat was inversely associated with non-advanced adenomas(OR = 0.71, 95%CI: 0.49-0.97). CONCLUSION A better adherence to the MD, specifically low intake of sugar-sweetened beverages and red meat as well as high intake of fish, is related to lower odds for advanced polyps. | Naomi Fliss-Isakov Revital Kariv Muriel Webb Dana Ivancovsky Dana Margalit Shira Zelber-Sagi | 2018 | World Journal of Gastroenterology2018,24,24: | 3 |
| 3 | Meningiomas involving the optic nerve:technical aspects and outcomes for a series of 50 patients显示文摘 | Margalit NS Lesser JB Moche J | 2003 | Neurosurgery2003,53,3: | 1 |
| 4 | Noise equivalent circuit of a semiconductor laser diode显示文摘 | HARDER C KATZ J MARGALIT S | 1982 | IEEE Journal of Quantum Electronics1982,18,3: | 1 |
| 5 | Comprehensive Analysis of Hydrogen Bonds in Regulatory Protein DNA-Complexes: In Search of Common Principles显示文摘 | Yael Mandel-Gutfreund Ora Schueler Hanah Margalit | 1995 | Journal of Molecular Biology1995,,2: | 1 |
| 6 | Prediction of immunodominant helper T cell antigenic sites from the primary sequence 显示文摘 | Margalit H Spouge JL Cornette JL | 1987 | J Immunol1987,138,7: | 1 |
| 7 | Microinvasive breast cancer:ER,PR,and HER-2/neu status and clinical outcomes after breast-conserving therapy or mastectomy显示文摘 | Margalit DN Sreedhara M Chen YH | 2013 | Ann Surg Oncol2013,20,3: | 1 |
| 8 | Microsatellie Spreading in the Huma Genome:Evolutionary Mechanisms and Structural Implications显示文摘 | NADIR E MARGALIT H GALLILY T | 1996 | Proc Natl Acad Sci1996,93,: | 1 |
| 9 | Lateral approach to anterolateral tumors at the foramen magnum:factors determining surgical procedure显示文摘 | Margalit NS Lesser JB Singer M | 2005 | Neurosurgery2005,56,2: | 1 |
| 10 | Clustering and conservation patterns of human microRNAs显示文摘 | Altuvia Y Landgraf P Lithwick G Elefant N Pfeffer S Aravin A Brownstein M J Tuschl T and Margalit H | | 0,,08: | 1 |
| 11 | Effect of ozone on neutrophil function in vitro 显示文摘 | Margalit M1 Attias E Attias D | 2001 | Clin Lab Haematol2001,23,4: | 1 |
| 12 | Electronic medical record use and physician-patient communieation:An observational study of Israeli primary care encounters显示文摘 | Margalit RS Roter D Dunevant MA | 2006 | Pat Educ Counsel2006,61,: | 1 |
| 13 | Hyaluronic acid-modified bioadhesive liposomes as local drug depots:effects of cellular and fluid dynamics on liposome retention at target sites显示文摘 | Yerushalmi N Margalit R | | 0,,01: | 1 |
| 14 | The influence of offer ing free transdermal nicotine patches on quit rates in a local health dep artment's smoking cessation program 显示文摘 | Anthony J Alberg Ruth Stashefsky Margalit | 2004 | Addictive Behaviors2004,29,9: | 1 |
| 15 | Beneficial effects of coculture with cumulus cell on blastocyst formation in a prospective trial with supernumerary human embryos显示文摘 | Margalit R | 1996 | J Assisted Reprod Genet1996,13,: | 1 |
| 16 | Cardiac output assessed by arterial thermodilution during exsanguination and fluid resuscitation:experimental validation against a reference technique显示文摘 | Friedman Z Berkenstadt H Margalit N | 2002 | Eur J Anaesthesiol2002,19,5: | 1 |
| 17 | The Effects of 1 Year of Specific Inspiratory Muscle Training in Patients With COPD显示文摘 | Marinella Beckerman Rasmi Magadle Margalit Weiner Paltiel Weiner | 2005 | Chest2005,,5: | 1 |
| 18 | Anti-nuclear envelope anti-bodies :Clinical associations 显示文摘 | Nesher G Margalit R Ashkenazi YJ | 2001 | Semin Arthritis Rheum2001,30,5: | 1 |
| 19 | Loneliness, Coherence and Companionship Among Children with Learning Disorders显示文摘 | M | 1996 | Educational Psychology1996,16,: | 1 |
| 20 | Loneliness and Coherence Among Preschool Children with LD显示文摘 | M | 1998 | Journal of learning Disabilities1998,31,: | 1 |