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16篇 您的检索式:作者名="Margarida F"
    题名 作者 年代 出处 被引量
1Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy:A single center report of 8 cases显示文摘This article describes cases of anti-tumor necrosis factor(TNF)-α-induced autoimmune hepatitis and evaluates the outcome of these patients in relation to their immunosuppressive strategy. A retrospective analysis of medical records was performed in our center, in order to detect cases of autoimmune hepatitis(AIH) associated with anti-TNF biologic agents. We describe and analyze eight cases of AIH following anti-TNF therapy, 7 with infliximab and 1 with adalimumab. A distinction should be made between induction of autoimmunity and clinically evident autoimmune disease. Liver biopsy is useful in detecting the role of the TNF-α antagonist in the development of AIH. The lack of relapse after discontinuing immunosuppressive therapy favors, as in this case series, an immune-mediated drug reaction as most patients with AIH have a relapse after treatment is suspended. Although AIH related to anti-TNF therapy is rare, a baseline immunological panel along with liver function tests should be performed in all patients with autoimmune disease before starting biologics.Susana Rodrigues Susana Lopes Fernando Magro Hélder Cardoso Ana Maria Horta e Vale Margarida Marques Eva Mariz Miguel Bernardes Joanne Lopes Fátima Carneiro Guilherme Macedo 2015World Journal of Gastroenterology2015,21,24:9
2Openness and Technological Innova- tions in Developing Countries: Evidence from Finn- Level Surveys显示文摘Almeida R Margarida F 2008The Journal of Development Studies2008,44,5:1
3Non-enzymatic browning in clarified cashew apple juice during thermal treatment:kinetics and process control显示文摘Leandro F Fabiano A N Margarida M A 0,,106:1
4Optimum zinc supplementation level in Nile tilapia Oreo chromis niloticus juveniles diets 显示文摘Marcelo V C Luiz E P Margarida M B F 2004Aquaculture2004,,238:1
5The effect of dietary sodium restriction on neurohumoral activity and renal dopaminergic re- sponse in patients with heart failure显示文摘Margarida A Antonio F Paulo B 2004Eur J Heart Fail2004,6,5:1
6Nutritional and lipid profiles in marine fish species from Brazil 显示文摘Carolina E F Margarida A S V Marisilda A R 2014Food Chem2014,160,:1
7Compliant contact force models in multibody dynamics : evolution of the Hertz contact theory 显示文摘MARGARIDA M PEDRO M PAULO F 2012Mechanism and Machine Theory2012,53,:1
8Optimum zinc supplementation level in Nile tilapia Oreochromis niolticus juveniles diets 显示文摘MARCELO V D C S LUIZ E P MARGARIDA M B F L 2004Aq- uaculture2004,238,:1
9Toxicity of parabens in testis mitochondria: a possible role on male infertility显示文摘MARTINS F MARGARIDA A OLIVEIRA M M 2008Biochimica et Biolahysica Acta-Bioeneretics2008,1777,:1
10WRF high resolution dynamical downscaling of ERA-Interim for Portugal显示文摘Pedro M. M. Soares Rita M. Cardoso Pedro M. A. Miranda Joana Medeiros Margarida Belo-Pereira Fátima Espirito-Santo 2012Climate Dynamics2012,,9:1
11Cluster Assignment for High- Performance Embedded VLIW Processors 显示文摘Viktor Lapinskii Margarida F Jacome 2002ACM Transactions on Design Automation of Electronic Systems2002,7,3:1
12Tm(DOTP)5-:A 23Na+ shift agent for perfused rat hearts显示文摘Buster D C Castro M Margarida C A Geraldes Carlos F G C Malloy C R Sherry A D Siemers T C 0,,01:1
13Influence of the Cation on the Solubility of CO2 and H2 in Ionic Liquids Based on the Bis (trifiuoromethylsulfonyl) imide Anion 显示文摘Johan Jacquemin Paseale Husson Vladimir Majer Margarida F Costa Gomes 2007Solution Chem2007,,36:1
14Non-enzymatic browning in clarified cashew apple juice during thermal treatment: Kinetics and process control 显示文摘LEANDRO F FABIANO A N MARGARIDA M A 2008Food Chemistry2008,106,1:1
15Relationship be tween plasma and brain levels and the anticonvulsant effect of lamotriginein rats显示文摘Margarida CB Vera L Arailcar F 2003Eur J Pharmacol2003,482,13:1
16The process of transformation' ofscientific and technological knowledge into economic valueconducted by biotechnology spin-ofFs显示文摘MARGARIDA F 2005Technovation2005,25,4:1
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