|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 2 | Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme显示文摘 | Christopher D. Turner Susan Chi Karen J. Marcus Tobey MacDonald Roger J. Packer Tina Young Poussaint Sridhar Vajapeyam Nicole Ullrich Liliana C. Goumnerova R. Michael Scott Caitlin Briody Christine Chordas Mary Ann Zimmerman Mark W. Kieran | 2007 | Journal of Neuro - Oncology2007，，1： | 1 |
| 3 | Effect of chronic administration of angiotensin coverting enzyme (ACE) Inhibitors on blood pressure and tissue ACE activity in SHR显示文摘 | Zimmerman BW Barclay ML | 1987 | Clin Exp Hypertens1987，9，23： | 1 |
| 4 | Optimal Utilization of Donor Grafts With Extended Criteria: A Single-Center Experience in Over 1000 Liver Transplants显示文摘 | Andrew M. Cameron R Mark Ghobrial Hasan Yersiz Douglas G. Farmer Gerald S. Lipshutz Sherilyn A. Gordon Michael Zimmerman Johnny Hong Thomas E. Collins Jeffery Gornbein Farin Amersi Michael Weaver Carlos Cao Tony Chen Jonathan R. Hiatt Ronald W. Busuttil | 2006 | Annals of Surgery2006，，6： | 1 |
| 5 | Severe insomnia is associated with more severe presentation and greater functional deficits in depression显示文摘 | Erin M. O’Brien Iwona Chelminski Diane Young Kristy Dalrymple Joshua Hrabosky Mark Zimmerman | 2011 | Journal of Psychiatric Research2011，，8： | 1 |
| 6 | Modeling underwater light climate in relation to sedimentation, resuspension, water quality and autotrophic growth显示文摘 | Elisabeth H.S. Van Duin Gerard Blom F. Johannes Los Robert Maffione Richard Zimmerman Carl F. Cerco Mark Dortch Elly P.H. Best | 2001 | Hydrobiologia (-)2001，，1： | 1 |
| 7 | Further evidence that the cutoff to define remission on the 17‐item Hamilton Depression Rating Scale should be lowered显示文摘 | Mark Zimmerman Jennifer Martinez Naureen Attiullah Michael Friedman Cristina Toba Daniela A. Boerescu Moataz Rahgeb | 2012 | Depress Anxiety2012，，2： | 1 |
| 8 | Concomitant pilocarpineduring head and neck irradiation reduces xerostomia显示文摘 | Zimmerman RP Mark RJ Tran LM | 1997 | Int J Ra-diat Oncol Biol Phys1997，36，： | 1 |
| 9 | Olfactory deficit detected by fMRI in early Alzheimer’s disease显示文摘 | Jianli Wang Paul J. Eslinger Richard L. Doty Erin K. Zimmerman Robert Grunfeld Xiaoyu Sun Mark D. Meadowcroft James R. Connor Joseph L. Price Michael B. Smith Qing X. Yang | 2010 | Brain Research2010，，： | 1 |
| 10 | Optimal Utilization of Donor Grafts With Extended Criteria: A Single-Center Experience in Over 1000 Liver Transplants显示文摘 | Andrew M. Cameron R Mark Ghobrial Hasan Yersiz Douglas G. Farmer Gerald S. Lipshutz Sherilyn A. Gordon Michael Zimmerman Johnny Hong Thomas E. Collins Jeffery Gornbein Farin Amersi Michael Weaver Carlos Cao Tony Chen Jonathan R. Hiatt Ronald W. Busuttil | 2006 | Annals of Surgery2006，，6： | 1 |
| 11 | Double-Blind, Placebo-Controlled Study of Amantadine Hydrochloride in the Treatment of Children With Autistic Disorder显示文摘 | BRYAN H. KING D. MARK WRIGHT BENJAMIN L. HANDEN LINMARIE SIKICH ANDREW W. ZIMMERMAN WILLIAM MCMAHON ERIN CANTWELL PABLO A. DAVANZO COLIN T. DOURISH ELISABETH M. DYKENS STEPHEN R. HOOPER CATHERINE A. JASELSKIS BENNETT L. LEVENTHAL JENNIFER LEVITT CATHERINE | 2001 | Journal of the American Academy of Child & Adolescent Psychiatry2001，，6： | 1 |
| 12 | Concomitant pilocarpine during head and neck irradiation reduces xerostomia显示文摘 | Zimmerman RP Mark RJ Tran LM | 1997 | Int J Radiat Oncol Biol Phys1997，36，： | 1 |
| 13 | Concomitant pilocarpine during head and neck iradiation reduces xerstomia显示文摘 | Zimmerman RP Mark RJ Tran LM | 1997 | Int Radial Oncol Biol Phys1997，36，： | 1 |
| 14 | Concomitant pilocarpine during head and neck irradiation reduces xerstomia显示文摘 | Zimmerman RP Mark RJ Tran LM | 1997 | Int J Radiat Oncol Biol Phys1997，36，： | 1 |
| 15 | Concomitant pilocarpine during head and neck irradiation reduces xerstomia显示文摘 | Zimmerman RP Mark B J Tran LM | 1997 | Int Radiat Oncol Biol Phys1997，36，： | 1 |
| 16 | Major depressive disorder and axis 1 diagnostic comorbidity显示文摘 | Mark Zimmerman Iwona Chelminski Wilson McDermut | 2002 | J Clin Psychiatry2002，63，： | 1 |
| 17 | Concomitant pilocarpine during head and neck irradiation reduces xerstomia 显示文摘 | Zimmerman R P Mark R J Tran L M | 1997 | Int Radiat Oncol Biol Phys1997，36，： | 1 |
| 18 | The relationship between borderline personality disorder and bipolar disorder显示文摘 | Mark Zimmerman Theresa A Morgan | 2013 | Dialogues Clin Neurosci2013，15，2： | 1 |
| 19 | Concomitant pilocarpine during head and neck irridiation reduces xerstomia 显示文摘 | Zimmerman RP Mark RJ Tran LM at al | 1997 | Int J Radiat Oncol Biol Phys1997，36，： | 1 |
| 20 | 大变形橄榄石动态重结晶的实验观测研究显示文摘本文利用高温高压大变形扭转实验,对富铁橄榄石大变形情况下的动态重结晶和颗粒尺度变化的特点进行了实验观测分析。富铁橄榄石集合体由纯铁橄榄石Fa100和圣卡罗橄榄石Fa10混合物经人工合成得到,试件的几何形状为圆柱体,直径9.6mm,高度4.86mm。实验在常角速率条件下进行,温度为1473K,围压为300MPa,剪应力为72~99MPa,剪应变率为1.35×10-4~3.11×10-4s-1,累积剪应变为3.98。对变形后样品的微结构进行了光学和扫描电镜的观测分析,得到橄榄石颗粒随应变增加而产生动态重结晶的具体物理图像,由EBSD观测结果给出了晶格取向随外加应变增加而产生的变化过程,利用两种统计方法得到了颗粒尺寸随应变增加而变化的过程,探讨了橄榄石动态重结晶的微观机制。与已有三轴压缩、简单剪切以及圣卡罗橄榄石的扭转变形结果进行了对比分析,同时对实验结果在地球物理方面的应用进行了讨论。 | 赵永红 ZIMMERMAN Mark KOHLSTEDT David ZHAO YongHong | 2013 | 岩石学报2013，29，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员