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| 1 | Blood Pressure Threshold Violations in the First 24 Hours After Admission for Acute Stroke: Frequency, Timing, Predictors, and Impact on Clinical Outcome显示文摘 | Martin A. Ritter Peter Kimmeyer Peter U. Heuschmann Rainer Dziewas Ralf Dittrich Darius G. Nabavi E Bernd Ringelstein | 2009 | Stroke2009，，2： | 2 |
| 2 | Acute regulation of parathyroid hormone by dietary phosphate显示文摘 | Martin D R Ritter C S Slatopolsky E | 2005 | Am J Phys-iol Endocrinol Metab2005，289，： | 1 |
| 3 | Acute regulation of parathyroid hormone by dietary phosphate显示文摘 | Martin D R Ritter C S Slatopolsky E | 2005 | Am J Physiol En- docrinol Metab2005，289，4： | 1 |
| 4 | Seizures after cerebrovascular events: Risk factors and clinical features显示文摘 | Julian Conrad Matthias Pawlowski Müjgan Dogan Stjepana Kovac Martin A. Ritter Stefan Evers | 2013 | Seizure: European Journal of Epilepsy2013，，4： | 1 |
| 5 | Percutaneous interventional reconstruction of the iliac arteries: primary and long-term success rate in selected TASC C and D lesions显示文摘 | J?rn O. Balzer Verena Gastinger Ralf Ritter Christopher Herzog Martin G. Mack Thomas Schmitz-Rixen Thomas J. Vogl | 2006 | European Radiology2006，，1： | 1 |
| 6 | Gastroesophageal reflux disease and mucosal injury with emphasis on short-segment Barrett’s esophagus and duodenogastroesophageal reflux显示文摘 | Stefan ?berg M.D. Manfred P. Ritter M.D. Peter F. Crookes M.D. Martin Fein M.D. Rodney J. Mason M.D. Michael Gadenst?tter M.D. Cedric G. Bremner M.D. Jeffrey H. Peters M.D. Tom R. DeMeester M.D | 1998 | Journal of Gastrointestinal Surgery1998，，6： | 1 |
| 7 | Duodenogastric reflux potentiates the injurious effects of gastroesophageal reflux显示文摘 | Martin Fein M.D. Adrian P. Ireland M.D. Manfred P. Ritter M.D. Jeffrey H. Peters M.D. Jeffrey A. Hagen M.D. Cedric G. Bremmer M.D. Tom R. DeMeester M.D | 1997 | Journal of Gastrointestinal Surgery1997，，1： | 1 |
| 8 | Inhibitory effect of anethole in nonimmune acute inflammation显示文摘 | Talita Perdig?o Domiciano Márcia Machado de Oliveira Dalalio Expedito Leite Silva Alessandra Mileni Versuti Ritter Camila Fernanda Estev?o-Silva Fernando Seara Ramos Silvana Martins Caparroz-Assef Roberto Kenji Nakamura Cuman Ciomar Aparecida Bersani-Amad | 2013 | Naunyn-Schmiedeberg’s Archives of Pharmacology2013，，4： | 1 |
| 9 | AP30 toward 400 kA 显示文摘 | Fiot L Ritter C | 2009 | Light Metals2009，，： | 1 |
| 10 | Diagnosis and management of fetal cardiac tumors: a multicenter experience and review of published reports显示文摘 | Deidre G. Holley Gerard R. Martin Joel I. Brenner Derek A. Fyfe James C. Huhta Charles S. Kleinman Samuel B. Ritter Norman H. Silverman | 1995 | Journal of the American College of Cardiology1995，，2： | 1 |
| 11 | Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease显示文摘 | Martin Fein Manfred P. Ritter Tom R. DeMeester Stefan ?berg Jeffrey H. Peters Jeffrey A. Hagen Cedric G. Bremner | 1999 | Journal of Gastrointestinal Surgery1999，，4： | 1 |
| 12 | Duodenoesophageal reflux induces esophageal adenocarcinoma without exogenous carcinogen显示文摘 | Martin Fein Ph.D. M.D. Jefiey H. Peters M.D. Para Chandrasoma M.D. Adrian P. Ireland M.D. Stefan ?berg M.D. Manfred P. Ritter M.D. Cedric G. Bremner M.D. Jefiey A. Hagen M.D. Tom R. DeMeester M.D | 1998 | Journal of Gastrointestinal Surgery1998，，3： | 1 |
| 13 | Slice Thickness Optimization for the Focused Ion Beam-Scanning Electron Microscopy 3D Tomography of Hierarchical Nanoporous Gold显示文摘The combination of focused ion beam (FIB) with scanning electron microscopy (SEM), also known as FIB-SEM tomography, has become a powerful 3D imaging technique at the nanometer scale. This method uses an ion beam to mill away a thin slice of material, which is then block-face imaged using an electron beam. With consecutive slicing along the z-axis and subsequent imaging, a volume of interest can be reconstructed from the images and further analyzed. Hierarchical nanoporous gold (HNPG) exhibits unique structural properties and has a ligament size of 15–110 nm and pore size of 5–20 nm. Accurate reconstruction of its image is crucial in determining its mechanical and other properties. Slice thickness is one of the most critical and uncertain parameters in FIB-SEM tomography. For HNPG, the slice thickness should be at least half as thin as the pore size and, in our approach, should not exceed 10 nm. Variations in slice thickness are caused by various microscope and sample parameters, e.g., converged ion milling beam shape, charging effects, beam drift, or sample surface roughness. Determining and optimizing the actual slice thickness variation appear challenging. In this work, we examine the influence of ion beam scan resolution and the dwell time on the mean and standard deviation of slice thickness. After optimizing the resolution and dwell time to achieve the target slice thickness and lowest possible standard deviation, we apply these parameters to analyze an actual HNPG sample. Our approach can determine the thickness of each slice along the z-axis and estimate the deviation of the milling process along the y-axis (slow imaging axis). For this function, we create a multi-ruler structure integrated with the HNPG sample. | Alexander Shkurmanov Tobias Krekeler Martin Ritter | 2022 | Nanomanufacturing and Metrology2022，5，2： | 1 |
| 14 | Laser-generated high entropy metallic glass nanoparticles as bifunctional electrocatalysts显示文摘High entropy metallic glass nanoparticles(HEMG NPs)are very promising materials for energy conversion due to the wide tuning possibilities of electrochemical potentials offered by their multimetallic character combined with an amorphous structure.Up until now,the generation of these HEMG NPs involved tedious synthesis procedures where the generated particles were only available on highly specialized supports,which limited their widespread use.Hence,more flexible synthetic approaches to obtain colloidal HEMG NPs for applications in energy conversion and storage are highly desirable.We utilized pulsed laser ablation of bulk high entropy alloy targets in acetonitrile to generate colloidal carbon-coated CrCoFeNiMn and CrCoFeNiMnMo HEMG NPs.An in-depth analysis of the structure and elemental distribution of the obtained nanoparticles down to single-particle levels using advanced transmission electron microscopy(TEM),energy-dispersive X-ray spectroscopy(EDX),X-ray diffraction(XRD),and Xray photoelectron spectroscopy(XPS)methods revealed amorphous quinary and senary alloy phases with slight manganese oxide/hydroxide surface segregation,which were stabilized within graphitic shells.Studies on the catalytic activity of the corresponding carbon-HEMG NPs during oxygen evolution and oxygen reduction reactions revealed an elevated activity upon the incorporation of moderate amounts of Mo into the amorphous alloy,probably due to the defect generation by atomic size mismatch.Furthermore,we demonstrate the superiority of these carbon-HEMG NPs over their crystalline analogies and highlight the suitability of these amorphous multi-elemental NPs in electrocatalytic energy conversion. | Jacob Johny Yao Li Marius Kamp Oleg Prymak Shun-Xing Liang Tobias Krekeler Martin Ritter Lorenz Kienle Christoph Rehbock Stephan Barcikowski Sven Reichenberger | 2022 | Nano Research2022，15，6： | 1 |
| 15 | 质子磁共振波谱评价不明原因的儿童发育迟缓显示文摘Developmental delay (DD) in children is a common socioeconomic problem with a prevalence of 1-2%. The cause of DD in children is often unknown, and magnetic resonance imaging plays an important role in evaluating children with DD, estimating long-term prognosis, and guiding therapeutic options. The aim of our study on children with DD was to elucidate 1) whether magnetic resonance spectroscopy (MRS) reveals abnormalities in cerebral metabolism and 2) whether there is a correlation between the cognitive performance and the concentration of brain metabolites, especially N-acetylaspartate (NAA), named in the literature a neuronalmarker. Using proton MRS of deep gray and central white matter, we measured concentrations of brain metabolites in 48 children, who were aged 1 mo to 13 y and had unexplained DD [develo- pmental quotient (DQ) between < 50 and 85] and normal magnetic resonance imaging examinations, and compared them with those of 23 age-matched normal control children. Children with DD were divided into three groups: mild (DQ 76-85),moderate (DQ 51-75), and severe (DQ < 50). We found no significant differences in metabolite concentrations, neither among the three groups of children with DD nor between patients and age-matched normal control children. Independent of the degree of mental retardation, the NAA concentrations of handicapped patients and normal children were comparable. We conclude that 1) brain metabolites, especially NAA, in children with unexplained DD are within normal limits, and 2) in most cases, proton MRS adds little information concerning cause of unexplained DD. | Martin E. Keller M. Ritter S. 刘凯 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，2，5： | 0 |
| 16 | Enhancing 3D Reconstruction Accuracy of FIB Tomography Data Using Multi‑voltage Images and Multimodal Machine Learning显示文摘FIB-SEM tomography is a powerful technique that integrates a focused ion beam(FIB)and a scanning electron microscope(SEM)to capture high-resolution imaging data of nanostructures.This approach involves collecting in-plane SEM imagesand using FIB to remove material layers for imaging subsequent planes,thereby producing image stacks.However,theseimage stacks in FIB-SEM tomography are subject to the shine-through effect,which makes structures visible from theposterior regions of the current plane.This artifact introduces an ambiguity between image intensity and structures in thecurrent plane,making conventional segmentation methods such as thresholding or the k-means algorithm insufficient.Inthis study,we propose a multimodal machine learning approach that combines intensity information obtained at differentelectron beam accelerating voltages to improve the three-dimensional(3D)reconstruction of nanostructures.By treatingthe increased shine-through effect at higher accelerating voltages as a form of additional information,the proposed methodsignificantly improves segmentation accuracy and leads to more precise 3D reconstructions for real FIB tomography data. | Trushal Sardhara Alexander Shkurmanov Yong Li Lukas Riedel Shan Shi Christian J.Cyron Roland C.Aydin Martin Ritter | 2024 | Nanomanufacturing and Metrology2024，7，1： | 0 |
| 17 | Intestinal complications in patients with Crohn's disease in the Brazilian public healthcare system between 2011 and 2020显示文摘BACKGROUND This is a secondary database study using the Brazilian public healthcare system database.AIM To describe intestinal complications(ICs)of patients in the Brazilian public healthcare system with Crohn’s disease(CD)who initiated and either only received conventional therapy(CVT)or also initiated anti-tumor necrosis factor(anti-TNF)therapy between 2011 and 2020.METHODS This study included patients with CD[international classification of diseases–10th revision(ICD-10):K50.0,K50.1,or K50.8](age:≥18 years)with at least one claim of CVT(sulfasalazine,azathioprine,mesalazine,or methotrexate).IC was defined as a CD-related hospitalization,pre-defined procedure codes(from rectum or intestinal surgery groups),and/or associated disease(pre-defined ICD-10 codes),and overall(one or more type of ICs).RESULTS In the 16809 patients with CD that met the inclusion criteria,the mean follow-up duration was 4.44(2.37)years.In total,14697 claims of ICs were found from 4633 patients.Over the 1-and 5-year of follow-up,8.3%and 8.2%of the patients with CD,respectively,presented at least one IC,of which fistula(31%)and fistulotomy(48%)were the most commonly reported.The overall incidence rate(95%CI)of ICs was 6.8(6.5–7.04)per 100 patient years for patients using only-CVT,and 9.2(8.8–9.6)for patients with evidence of anti-TNF therapy.CONCLUSION The outcomes highlighted an important and constant rate of ICs over time in all the CD populations assessed,especially in patients exposed to anti-TNF therapy.This outcome revealed insights into the real-world treatment and complications relevant to patients with CD and highlights that this disease remains a concern that may require additional treatment strategies in the Brazilian public healthcare system. | Ligia Yukie Sassaki Adalberta Lima Martins Rodrigo Galhardi-Gasparini Rogerio Saad-Hossne Alessandra Mileni Versut Ritter Tania Biatti Barreto Taciana Marcolino Bruno Balula Claudia Yang-Santos | 2023 | World Journal of Clinical Cases2023，11，14： | 0 |
| 18 | Intestinal complications in Brazilian patients with ulcerative colitis treated with conventional therapy between 2011 and 2020显示文摘BACKGROUND This was an observational, descriptive, and retrospective study from 2011 to 2020 from the Department of Informatics of the Brazilian Healthcare System database.AIM To describe the intestinal complications(IC) of patients with ulcerative colitis(UC) who started conventional therapies in Brazil’s public Healthcare system.METHODS Patients ≥ 18 years of age who had at least one claim related to UC 10th revision of the International Statistical Classification of Diseases and Related Health Problems(ICD-10) code and at least 2 claims for conventional therapies were included. IC was defined as at least one claim of: UC-related hospitalization, procedures code for rectum or intestinal surgeries, and/or associated disease defined by ICD-10 codes(malignant neoplasia of colon, stenosis, hemorrhage, ulcer and other rectum or anus disease, megacolon, functional diarrhea volvulus, intussusception and erythema nodosum). Descriptive statistics, annual incidence, and incidence rate(IR) [per 100 patient-years(PY)] over the available follow-up period were calculated.RESULTS In total, 41229 UC patients were included(median age, 48 years;65% women) and the median(interquartile range) follow-up period was 3.3(1.8-5.3) years. Conventional therapy used during follow-up period included: mesalazine(87%), sulfasalazine(15%), azathioprine(16%) or methotrexate(1%) with a median duration of 1.9(0.8-4.0) years. Overall IR of IC was 3.2 cases per 100 PY. Among the IC claims, 54% were related to associated diseases, 20% to procedures and 26% to hospitalizations. The overall annual incidence of IC was 2.9%, 2.6% and 2.5% in the first, second and third year after the first claim for therapy(index date), respectively. Over the first 3 years, the annual IR of UC-related hospitalizations ranged from 0.8% to 1.1%;associated diseases from 0.9% to 1.2%-in which anus or rectum disease, and malignant neoplasia of colon were the most frequently reported;and procedure events from 0.6% to 0.7%, being intestinal resection and polyp removal the most frequent ones.CONCLUSION Study shows that UC patients under conventional therapy seem to present progression of disease developing some IC, which may have a negative impact on patients and the burden on the health system. | Adalberta Lima Martins Rodrigo Galhardi Gasparini Ligia Yukie Sassaki Rogerio Saad-Hossne Alessandra Mileni Versut Ritter Tania Biatti Barreto Taciana Marcolino Claudia Yang Santos | 2023 | World Journal of Gastroenterology2023，29，8： | 0 |
| 19 | Biliary tract cancer stem cells-translational options and challenges显示文摘Management of biliary tract cancer remains challenging. Tumors show high recurrence rates and therapeutic resistance, leading to dismal prognosis and short survival. The cancer stem cell model states that a tumor is a heterogeneous conglomerate of cells, in which a certain subpopulation of cells-the cancer stem cells-possesses stem cell properties. Cancer stem cells have high clinical relevance due to their potential contributions to development, progression and aggressiveness as well as recurrence and metastasis of malignant tumors. Consequently, reliable identification of as well as pharmacological intervention with cancer stem cells is an intensively investigated and promising research field. The involvement of cancer stem cells in biliary tract cancer is likely as a number of studies demonstrated their existence and the obvious clinical relevance of several established cancer stem cell markers in biliary tract cancer models and tissues. In the present article, we review and discuss the currently available literature addressing the role of putative cancer stem cells in biliary tract cancer as well as the connection between known contributors of biliary tract tumorigenesis such as oncogenic signaling pathways, micro-RNAs and the tumor microenvironment with cancer stem cells. | Christian Mayr Matthias Ocker Markus Ritter Martin Pichler Daniel Neureiter Tobias Kiesslich | 2017 | World Journal of Gastroenterology2017，23，14： | 0 |
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