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| 1 | 英国胃肠病学会关于胃癌风险患者的诊断和管理指南显示文摘胃癌预后较差,部分原因在于诊断较晚。胃癌的危险因素包括幽门螺杆菌(H.pylori,HP)感染和胃癌家族史,尤其是遗传性弥漫性胃癌和恶性贫血。胃癌发展的阶段包括慢性胃炎、胃黏膜萎缩(GA)、胃黏膜肠化生(GIM)和异型增生。胃癌早期发现和提高生存率的关键是在内镜检查前以非侵入性方式识别高危人群。然而,尽管生物标志物可能有助于检测慢性萎缩性胃炎,但尚无足够的证据支持其用于人群筛查。高质量内镜检查是胃癌早期发现的重要组成部分,图像增强内镜结合组织病理学活检是GA和GIM最佳的诊断方法,并能准确进行风险分层。按照悉尼标准从胃窦、角切迹、小弯和大弯进行活检,既能明确诊断,也能对胃癌进行风险分层。理想状态应当是在高质量内镜检查中对GA或GIM区域活检。英国属于低危地区,可根据需要接受常规诊断性胃镜检查,但没有足够证据支持筛查,对于广泛GA或GIM的患者,每3年检查内镜。对于胃异型增生和早期癌,只要满足标准,内镜下黏膜切除术或内镜黏膜下剥离术的治疗有效,成功率高,复发率低。 | Matthew Banks David Graham Marnix Jansen TakujiGotoda Sergio Coda Massimiliano di Pietro NoriyaUedo Pradeep Bhandari D Mark Pritchard Ernst J Kuipers Manuel Rodriguez-Justo Marco R Novelli KrishRagunath Neil Shepherd Mario Dinis-Ribeiro 乌雅罕(译) 张冬雪(译) 牛占岳(校) 刘鑫(校) 丁士刚(译/校) | 2020 | 中华胃肠内镜电子杂志2020，7，2： | 10 |
| 2 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 3 | Production and characterisation of polyclonal antibodies to the common moiety of some organophosphorous pesticides and development of a generic type ELISA显示文摘 | Banks J N Chaudhry M Q Matthews W A | 1998 | Food Agric Immunol1998，10，： | 1 |
| 4 | Production and characterization of poly clonal antibodies to the common moiety of wome organophosphorus pesticides and development of a generic type ELISA 显示文摘 | Banks J N Chaudhry M Q Matthews W A | 1998 | Food and Agricultural Immunology1998，10，： | 1 |
| 5 | Production and charcterisation of polyclonal antibodies to the common moiety of some organophosphorous pesticides and development of a generic type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food and Agricultural Immunology1998，10，4： | 1 |
| 6 | Production and charcterisation of polyclonal antibodies to the common moiety of some organophosphorous pesticides and development of a generic type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food and Agricultural Immunology1998，10，4： | 1 |
| 7 | Production and characterisation of polyelonal antibodies to the common moiety of some organophosphorus pesticides and development of a generic type ELISA 显示文摘 | Banks J N Chaudhry M Q Matthews W A | 1998 | Food Agric Immun1998，10，4： | 1 |
| 8 | Production and characterisation of polyclonal anbodies to the common moiety of some organophosphorous pesticides and development of a generic type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food and Agric Immunology1998，10，： | 1 |
| 9 | Production and characterisation of polyclonal antibodies to the common moiety of some organophosphorous pesticides and development of a generic type ELISA 显示文摘 | Banks J N Chaudhry M Q Matthews W A | 1998 | Food and Agricultural Immunology1998，10，4： | 1 |
| 10 | Multi‐centre reproducibility of diffusion MRI parameters for clinical sequences in the brain显示文摘 | Matthew Grech‐Sollars Patrick W. Hales Keiko Miyazaki Felix Raschke Daniel Rodriguez Martin Wilson Simrandip K. Gill Tina Banks Dawn E. Saunders Jonathan D. Clayden Matt N. Gwilliam Thomas R. Barrick Paul S. Morgan Nigel P. Davies James Rossiter Dorothee | 2015 | NMR Biomed2015，，： | 1 |
| 11 | Production and Characterisation of Polyclonal Anbodies to the Common Moiety of Some Organophosphorous Pesticides and Development of a Generic Type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food Agric Immuno1998，10，： | 1 |
| 12 | What sleep characteristics predict cognitive decline in the elderly?显示文摘 | Keage HA Banks S Yang KL Morgan K Brayne C Matthews FE | 2012 | Sleep Medicine2012，13，7： | 1 |
| 13 | Production and Characterization of PolyClonal Antibodies to the Common Moiety of Wome Organophosphorus Pesticides and Developmentof a Generic Type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food and Agricultural Immunology1998，10，： | 1 |
| 14 | High resolution colonoscopy in a bowel cancer screening program improves polyp detection显示文摘AIM:To compare high resolution colonoscopy(Olympus Lucera) with a megapixel high resolution system(Pentax HiLine) as an in-service evaluation.METHODS:Polyp detection rates and measures of performance were collected for 269 colonoscopy procedures.Five colonoscopists conducted the study over a three month period,as part of the United Kingdom bowel cancer screening program.RESULTS:There were no differences in procedure duration(χ2 P = 0.98),caecal intubation rates(χ2 P = 0.67),or depth of sedation(χ2 P = 0.64).Mild discomfort was more common in the Pentax group(χ2 P = 0.036).Adenoma detection rate was significantly higher in the Pentax group(χ2 test for trend P = 0.01).Most of the extra polyps detected were flat or sessile adenomas.CONCLUSION:Megapixel definition colonoscopes improve adenoma detection without compromising other measures of endoscope performance.Increased polyp detection rates may improve future outcomes in bowel cancer screening programs. | Matthew R Banks Rehan Haidry M Adil Butt Lisa Whitley Judith Stein Louise Langmead Stuart L Bloom Austin O' Bichere Sara McCartney Kalpesh Basherdas Manuel Rodriguez-Justo Laurence B Lovat | 2011 | World Journal of Gastroenterology2011，17，38： | 1 |
| 15 | Dual Actions of Volatile Anesthetics on GABAA IPSCs: Dissociation of Blocking and Prolonging Effects显示文摘 | Matthew I. Banks Robert A. Pearce | 1999 | Anesthesiology1999，，1： | 1 |
| 16 | Production and Characterisation of Polyclonal Anbodies to the Common Moiety of Some Organophosphorous Pesticides and Development of a Generic Type ELISA显示文摘 | BANKS J N CHAUDHRY M Q MATTHEWS W A | 1998 | Food and Agric Immunology1998，10，： | 1 |
| 17 | 丹麦NOMA Lab餐厅显示文摘NOMAL Lab譬厅在知名的mew0Hds50b划com厨站连续两年蝉联餐厅粪冠军.这样的荣誉让餐厅对新的室内装饰改造有了比以往更高的期望,他们希望创造一座激发想象的试验馆。 | Kasper Guldager Jorgensen Kim Herforth Nielsen Andr van Leth Lila Held Morten Norman Lund Lars-Erik Eriksson Pedram Seddighzadeh Matthew Scarlett Bjork Christensen Kyle Baumgardner Elliot Mistur Tore Banke Simon McKenzie Jacob Hilmer Adam Mork 代照 | 2012 | 现代装饰2012，，7： | 0 |
| 18 | Risk of lymph node metastases in patients with T1b oesophageal adenocarcinoma: A retrospective single centre experience显示文摘AIM To assess clinical outcomes for submucosal (T1b) oesophageal adenocarcinoma (OAC) patients managed with either surgery or endoscopic eradication therapy.METHODS Patients found to have T1b OAC following endoscopic resection between January 2008 to February 2016 at University College London Hospital were retrospectively analysed. Patients were split into low-risk and high-risk groups according to established histopathological criteria and were then further categorised according to whether they underwent surgical resection or conservative management. Study outcomes include the presence of lymphnode metastases, disease-specific mortality and overall survival. RESULTS A total of 60 patients were included; 22 patients were surgically managed (1 low-risk and 21 high-risk patients) whilst 38 patients were treated conservatively (12 low-risk and 26 high-risk). Overall, lymph node metastases (LNM) were detected in 10 patients (17%); six of these patients had undergone conservative management and LNM were detected at a median of 4 mo after endoscopic mucosal resection (EMR). All LNM occurred in patients with highrisk lesions and this represented 21% of the total high-risk lesions. Importantly, there was no statistically significant difference in tumor-related deaths between those treated surgically or conservatively (P = 0.636) and disease-specific survival time was also comparable between the two treatment strategies (P = 0.376).CONCLUSION T1b tumours without histopathological high-risk markers of LNM can be treated endoscopically with good outcomes. In selected patients, endoscopic therapy may be appropriate for high-risk lesions. | David Graham Nejc Sever Cormac Magee William Waddingham Matthew Banks Rami Sweis Hannah Al-Yousuf Miriam Mitchison Durayd Alzoubaidi Manuel Rodriguez-Justo Laurence Lovat Marco Novelli Marnix Jansen Rehan Haidry | 2018 | World Journal of Gastroenterology2018，24，41： | 0 |
| 19 | 丹麦NOMA食品实验室显示文摘由3XN负责的NOMA食品实验室室内设计项目巧妙地将烹饪与建筑融为一体.并为北欧菜肴打造出最佳的效果呈现舞台。 | KIm Herforth Nielsen Kasper Guldager J rgensen Andr van leth lila Held Morten Norman Lund Lars-Erik Eriksson Pedram Seddighzadeh Matthew Scarlett BjHrk Christensen Kyle Baumgardner Elliot Mistur Tore Banke Simon McKenzie Jacob Hilmer Pauline Pan | 2012 | 设计家2012，，2： | 0 |
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