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| 1 | 改良的ABTS^+法及其在优化抗氧化活性物质提取中的应用显示文摘目的 对测定抗氧化活性的ABTS+ 法进行改良 ,以提高分析速度、降低分析成本 ,并将该方法用于水果中抗氧化活性物质提取条件的优化。方法 在酶标板上以Trolox为标准对照 ,测定抗氧化物质对预先制备的自由基ABTS+ 的清除能力。用不同浓度的乙醇和重亚硫酸钠为提取液 ,在不同的温度和溶剂 水果比条件下 ,提取水果blackcurrant中的抗氧化活性物质 ,寻找从单位重量水果中提取抗氧化活性水平较高的条件。结果 该方法的测量误差小于 0 2 ,测得的 14种标准样品的抗氧化活性与文献报道基本一致。用乙醇从水果blackcurrant中提取抗氧化活性物质的条件为 :在 17℃上下、每克水果用 2 0毫升、6 7%左右浓度的乙醇进行提取。而用重亚硫酸钠从水果blackcurrant中提取抗氧化活性物质的条件为 :在 30℃上下、每克水果用2 0毫升、30 0mg L左右浓度的重亚硫酸钠进行提取。结论 改良的ABTS+ 法测定物质的抗氧化活性 ,方法简便可行 ,可用于优化抗氧化活性物质的提取 。 | 韩光亮 李翠梅 Eduardo Cacace G Mazza 杨晓光 | 2004 | 卫生研究2004，33，5： | 53 |
| 2 | Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery?显示文摘Indocyanine green(ICG) kinetics(PDR/R15) used to quantitatively assess hepatic function in the perioperative period of major resective surgery and liver transplantation have been the object of an extensive, updated and critical review. New, non invasive bedside monitors(pulse dye densitometry technology) make this opportunity widely available in clinical practice. After having reviewed basic concepts of hepatic clearance, we analysed the most common indications ICG kinetic parameters have nowadays in clinical practice, focusing in particular on the diagnostic and prognostic role of PDR and R15 in the perioperative period of major liver surgery and liver transplantation. As recently pointed out, even if of extreme interest, ICG clearance parameters have still some limitations, to be considered when using these tests. | Andrea De Gasperi Ernestina Mazza Manlio Prosperi | 2016 | World Journal of Hepatology2016，8，7： | 22 |
| 3 | 微波提取法对樱桃、猕猴桃和枸杞多糖特性的影响显示文摘微波提取是近年来发展迅速的天然产物提取技术之一。为考察微波提取对多糖得率、结构及生物学功能的影响,论文采用微波功率1000W和提取温度140℃,以不同提取时间5,10和20min分别对樱桃、猕猴桃和枸杞中多糖进行提取。结果表明,微波提取多糖的得率、相对分子质量和抗氧化性低于传统提取方法,随着微波提取时间延长,多糖相对分子质量逐步降低,但多糖得率与抗氧化性无显著变化;微波提取得到的多糖在单糖组成上与传统提取方法有一定的差异。该研究结果对应用微波提取水果多糖条件的选择及多糖品质控制有一定的参考价值。 | 范会平 符锋 Giuseppe Mazza 胡小松 廖小军 | 2009 | 农业工程学报2009，25，10： | 18 |
| 4 | Apparent diffusion coefficient by diffusion-weighted magnetic resonance imaging as a sole biomarker for staging and prognosis of gastric cancer显示文摘Objective:To investigate the role of apparent diffusion coefficient(ADC)from diffusion-weighted magnetic resonance imaging(DW-MRI)when applied to the 7th TNM classification in the staging and prognosis of gastric cancer(GC).Methods:Between October 2009 and May 2014,a total of 89 patients with non-metastatic,biopsy proven GC underwent 1.5T DW-MRI,and then treated with radical surgery.Tumor ADC was measured retrospectively and compared with final histology following the 7th TNM staging(local invasion,nodal involvement and according to the different groups—stage I,II and III).Kaplan-Meier curves were also generated.The follow-up period is updated to May 2016.Results:Median follow-up period was 33 months and 45/89(51%)deaths from GC were observed.ADC was significantly different both for local invasion and nodal involvement(P<0.001).Considering final histology as the reference standard,a preoperative ADC cut-off of 1.80×10–3 mm2/s could distinguish between stages I and II and an ADC value of≤1.36×10–3 mm2/s was associated with stage III(P<0.001).Kaplan-Meier curves demonstrated that the survival rates for the three prognostic groups were significantly different according to final histology and ADC cut-offs(P<0.001).Conclusions:ADC is different according to local invasion,nodal involvement and the 7th TNM stage groups for GC,representing a potential,additional prognostic biomarker.The addition of DW-MRI could aid in the staging and risk stratification of GC. | Francesco Giganti Alessandro Ambrosi Damiano Chiari Elena Orsenigo Antonio Esposito Elena Mazza Luca Albarello Carlo Staudacher Alessandro Del Maschio Francesco De Cobelli | 2017 | Chinese Journal of Cancer Research2017，29，2： | 15 |
| 5 | 澳大利亚Danielle Mazza教授全科医疗案例分析--产后抑郁症显示文摘面对妇女健康领域的诸多问题,全科医生需要学习并掌握全面的、最新的妇女保健知识。澳大利亚Monash大学医学、护理和卫生科学部全科医学系主任丹尼尔·马扎(DanielleMazza)教授为我们提供了一本很实用的学习用书,其主编的《Women’s HealthinGeneralPractice》,涵盖了从少女至更年期妇女的整个生命周期中可能遇到的所有问题,包括月经问题、避孕、流产、不孕不育、孕前及产后保健、乳腺疾病、泌尿系疾病以及家庭暴力等。 | Danielle Mazza | 2015 | 中国全科医学2015，18，4： | 5 |
| 6 | Randomized clinical trial comparing survival after D1 or D2 gastrectomy for gastric cancer显示文摘 | M. Degiuli M. Sasako A. Ponti A. Vendrame M. Tomatis C. Mazza A. Borasi L. Capussotti G. Fronda M. Morino | 2014 | Br J Surg2014，，2： | 5 |
| 7 | A network of sex and competition: The promiscuous mating system of an invasive weevil显示文摘 | Alberto Francesco INGHILESI Giuseppe MAZZA Rita CERVO Alessandro CINI | 2015 | Current Zoology2015，61，1： | 4 |
| 8 | Computational Aspects of Dam Risk Analysis: Findings and Challenges显示文摘水电是一种清洁、可再生,且对环境友好的能源。全球每年的水力发电量达到3930 TW·h,占全球总发电量的16%,同时占可再生能源发电量的78%(2015年)。水电和气候变化具有双重的关系。一方面,水电作为一种重要的可再生能源,对于避免温室气体排放和减缓全球变暖贡献显著;另一方面,气候变化会改变河道流量,进而影响水资源可用量和水力发电。水电对于减少温室气体排放和保障能源供应至关重要。与常规燃煤电厂相比,水电每年可避免3×109 t CO_2的排放,占全球年CO_2排放量的9%。除了对电力行业的贡献,水电项目还可作为多功能水库的融资工具,以及水资源应对气候变化影响的一项适应性措施,这是因为水库的蓄水可作为气候变化的缓冲器,有大水库调节的流域更能适应水资源变化,而不容易受到气候变化的影响。从全球层面来看,预期气候变化对现有全球水力发电的整体影响较小,甚至可能产生一些积极影响。然而,世界不同地区甚至各个国家内部可能存在巨大差异。总之,对水电的解读为:水电是一种廉价、成熟的技术,对减缓气候变化有重大贡献,且可以在水资源适应气候变化中发挥重要作用。有必要关注并减轻巨大的环境压力和社会成本,预计未来几十年内可新增水电装机容量1000 GW。 | Ignacio Escuder-Bueno Guido Mazza Adrian Morales-Torres Jesica T. Castillo-Rodriguez | 2016 | Engineering2016，2，3： | 4 |
| 9 | Intraoperative Management and Repair of Bile Duct Injuries Sustained during 10,123 Laparoscopic Cholecystectomies in a High-Volume Referral Center显示文摘 | Juan Pekolj Fernando A. Alvarez Martin Palavecino Rodrigo Sánchez Clariá Oscar Mazza Eduardo de Santiba?es | 2013 | Journal of the American College of Surgeons2013，，5： | 3 |
| 10 | 微波处理对葡萄种子油物理化学性质的影响显示文摘研究了葡萄种子微波干燥对葡萄种子油物理化学性质的影响。结果表明 ,微波处理提高了葡萄种子油的产率 ,增加了油的粘度、共轭双烯值、过氧化值和皂化值 ,降低了叶绿素和类胡萝卜素含量 (K41 0 和 K670 值 )及对甲氧基苯胺值。醇洗葡萄种子去单宁处理降低了油色素值 ,提高了共轭双烯值、对甲氧基苯胺值、过氧化值和皂化值。 | 梁俊 陈萍 B Dave Oomah David Godfrey Giuseppe Mazza | 2002 | 西北农林科技大学学报(自然科学版)2002，30，1： | 3 |
| 11 | Endoscopic ultrasound diagnostic gain over computed tomography and magnetic resonance cholang-iopancreatography in defining etiology of idiopathic acute pancreatitis显示文摘BACKGROUND About 10%-30%of acute pancreatitis remain idiopathic(IAP)even after clinical and imaging tests,including abdominal ultrasound(US),contrast-enhanced computed tomography(CECT)and magnetic resonance cholangiopancreatography(MRCP).This is a relevant issue,as up to 20%of patients with IAP have recurrent episodes and 26%of them develop chronic pancreatitis.Few data are available on the role of EUS in clarifying the etiology of IAP after failure of one or more cross-sectional techniques.AIM To evaluate the diagnostic gain after failure of one or more previous crosssectional exams.METHODS We retrospectively collected data about consecutive patients with AP and at least one negative test between US,CECT and MRCP,who underwent linear EUS between January 2017 and December 2020.We investigated the EUS diagnostic yield and the EUS diagnostic gain over different combinations of these crosssectional imaging techniques for the etiologic diagnosis of AP.Types and frequency of EUS diagnosis were also analyzed,and EUS diagnosis was compared with the clinical parameters.After EUS,patients were followed-up for a median of 31.5 mo to detect cases of pancreatitis recurrence.RESULTS We enrolled 81 patients(63%males,mean age 61±18,23%with previous cholecystectomy,17%with recurrent pancreatitis).Overall EUS diagnostic yield for AP etiological diagnosis was 79%(20%lithiasis,31%acute on chronic pancreatitis,14%pancreatic solid or cystic lesions,5%pancreas divisum,5%autoimmune pancreatitis,5%ductal abnormalities),while 21%remained idiopathic.US,CECT and MRCP,taken alone or in combination,led to AP etiological diagnosis in 16(20%)patients;among the remaining 65 patients,49(75%)obtained a diagnosis at EUS,with an overall EUS diagnostic gain of 61%.Sixty-eight patients had negative US;among them,EUS allowed etiological diagnosis in 59(87%).Sixty-three patients had a negative CECT;among them,47(74%)obtained diagnosis with EUS.Twenty-four had a negative MRCP;among them,20(83%)had EUS diagnosis.Twenty-one had negative CT+MRCP,of which 17(81%)had EUS diagnosis,with a EUS diagnostic gain of 63%.Patients with biliary etiology and without previous cholecystectomy had higher median values of alanine aminotransferase(154 vs 25,P=0.010),aspartate aminotransferase(95 vs 29,P=0.018),direct bilirubin(1.2 vs 0.6,P=0.015),gammaglutamyl transpeptidase(180 vs 48,P=0.006)and alkaline phosphatase(150 vs 72,P=0.015)Chronic pancreatitis diagnosis was more frequent in patients with recurrent pancreatitis at baseline(82%vs 21%,P<0.001).During the follow-up,AP recurred in 3 patients,one of which remained idiopathic.CONCLUSION EUS is a good test to define AP etiology.It showed a 63%diagnostic gain over CECT+MRCP.In suitable patients,EUS should always be performed in cases of IAP.Further prospective studies are needed. | Stefano Mazza Biagio Elvo Clara Benedetta Conti Andrea Drago Maria Chiara Verga Sara Soro Annalisa De Silvestri Fabrizio Cereatti Roberto Grassia | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，6： | 3 |
| 12 | 富含anthocyanin的水果提取物对血管内皮细胞产生PGE_2的影响研究显示文摘目的研究富含anthocyanin的水果提取物对血管内皮细胞产生PGE2的影响.方法将人类正常的血管内皮细胞CRL-2606在Kaighn's F12K培养基中(补加有10%FBS,0.1mg/ml肝素,0.03mg/ml的ECGS,50μg/ml链霉素和500U/ml青霉素)37℃、5%CO2的条件下培养至接近融合,然后在含有从水果中提取出的anthocyanin的F12K培养基中添加或不添加100ng/mlLPS,继续培养18小时,测定细胞生存率,并将培养液离心,收集上清液,用STAT-Prostaglandin E2 EIA Kit试剂盒测定培养基上清液中的PGE2浓度.结果当CRL-2606细胞暴露于300μg/ml或以上的Chokeberry提取物中时,细胞的生存率低于60%,且表现出一定的剂量效应关系.而50~400μg/ml的蓝莓提取物和100~700μg/ml的黑醋栗提取物未显示细胞毒性.LPS刺激可使细胞PEG2释放量增加一倍以上,蓝莓提取物可明显抑制由于LPS刺激引起的PGE2释放增加,100μg/ml的蓝莓提取物可完全抑制此作用而使其含量维持于正常水平.700μg/ml的黑醋栗提取物对处于LPS刺激下的CRL-2606细胞具有一定的抑制PGE2释放作用.而对于处于LPS刺激下的细胞,500μg/ml以上的Chokeberry提取物能抑制PGE2的释放.结论富含anthocyanin的黑醋栗、蓝莓以及Chokeberry提取物可以抑制由LPS刺激引起的血管内皮细胞释放PEG2增加的作用,具有一定的抗炎、抗氧化作用. | 韩光亮 李翠梅 Mazza G 杨晓光 | 2005 | 卫生研究2005，34，5： | 3 |
| 13 | Arthroscopic vs open ankle arthrodesis:A prospective case series with seven years follow-up显示文摘BACKGROUND The osteoarthritis of the ankle,although less common than other joints,is associated with severe functional limitation.Surgical options are ankle arthroscopic debridement,osteotomies,ankle arthrodesis and ankle arthroplasty.Ankle arthroplasty is increasingly used thanks to the new implants design,but ankle arthrodesis still represents the most used technique and it can be performed arthroscopically or with an open procedure.AIM To compare mid-term results of arthroscopic vs open ankle arthrodesis of patients affected by end-stage ankle arthritis.METHODS This study enrolled 23 patients,which underwent ankle arthrodesis.The patients were divided into 2 groups:group A(open procedure;n=11)and group B(arthroscopic procedure,n=12),the two groups were homogeneous with regard to age and body mass index(P=0.347).The American Orthopaedic Foot and Ankle score(AOFAS),Freiburg Ankle score(FAS)and visual analogue scale for pain intensity were evaluated preoperatively,at six months and at final follow-up of 7.6 years in group A and 7.3 years in group B(P=0.364).RESULTS Patients in the arthroscopic group showed better results at six-month follow-up compared to the open group at the AOFAS(group A,62.2;group B,78.5;P<0.05)and the FAS(group A,61.1;group B,70.3;P=0.015)scores.Pain relief was achieved in both groups at six-month follow-up(group A,1.4;group B,0.9;P=0.162).Both open and arthroscopic groups showed improved clinical outcomes from baseline to final follow-up(P>0.05).Hospital stay was shorter in group B than in group A(P=0.001).More complications were reported in the open group than in the arthroscopic group(P=0.459).CONCLUSION The arthroscopic and the open arthrodesis are valid and safe options for the treatment of ankle arthritis on the basis of clinical outcomes at 7 years follow-up.Moreover,the arthroscopic treatment shows faster improvement at six-month follow-up in comparison with the open group. | Federico Morelli Giorgio Princi Matteo Romano Cantagalli Marco Rossini Ludovico Caperna Daniele Mazza Andrea Ferretti | 2021 | World Journal of Orthopedics2021，12，12： | 3 |
| 14 | Chest pain caused by multiple exostoses of the ribs: A case report and a review of literature显示文摘The aim of this paper is to report an exceptional case of multiple internal exostoses of the ribs in a young patient affected by multiple hereditary exostoses(MHE) coming to our observation for chest pain as the only symptom of an intra-thoracic localization. A 16 years old patient with familiar history of MHE came to our observation complaining a left-sided chest pain. This pain had increased in the last months with no correlation to a traumatic event. The computed tomography(CT) scan revealed the presence of three exostoses located on the left third, fourth and sixth ribs, all protruding into the thoracic cavity, directly in contact with visceral pleura. Moreover, the apex of the one located on the sixth rib revealed to be only 12 mm away from pericardium. Patient underwent video-assisted thoracoscopy with an additional 4-cm mini toracotomy approach. At the last 1-year followup, patient was very satisfied and no signs of recurrence or major complication had occured. In conclusion, chest pain could be the only symptom of an intra-thoracic exostoses localization, possibly leading to serious complications. Thoracic localization in MHE must be suspected when patients complain chest pain. A chest CT scan is indicated to confirm exostoses and to clarify relationship with surrounding structures. Video-assisted thoracoscopic surgery can be considered a valuable option for exostoses removal, alone or in addiction to a mini-thoracotomy approach, in order to reduce thoracotomy morbidity. | Daniele Mazza Mattia Fabbri Cosma Calderaro Carlo Iorio Luca Labianca Camilla Poggi Francesco Turturro Antonello Montanaro Andrea Ferretti | 2017 | World Journal of Orthopedics2017，8，5： | 2 |
| 15 | 复合手术室中不可触及的肺结节的同步定位和胸腔镜切除显示文摘随着肺结节检出率的提高,胸腔镜肺楔形切除术是部分小结节可靠的检出方式,如果小结节无法定位,胸腔镜手术则可能中转开胸手术。本研究纳入2016年4月到2019年11月共39例图像引导的胸腔镜手术(iVATS)。研究报告了对不可触及的未确诊肺结节进行同步定位和胸腔镜切除的经验。纳入标准为:病变小(<1 cm)、深(距表面>1 cm)、亚实性或位于营养不良区域内。使用锥形束CT进行扫描并用定位钩及线圈进行术中标记,定位结节大小为(12±6)mm,从病变深缘到胸膜表面的距离为(24±9)mm,共使用20根定位钩19个线圈进行定位。 | 施琴朗(编译) Mazza F Venturino M Peano E | 2021 | 中华医学杂志2021，101，33： | 2 |
| 16 | 树莓(Rubus idaeus)种子油的性质研究(英文)显示文摘研究了空气干燥树莓种子、溶剂提取和室温压榨提取种子油的物理性质和化学性质以及维生素 E组成和含量。结果表明 ,树莓种子出油率为 9.0 4 % ;1 0 % ( v/v)树莓种子油的正己烷溶液叶绿素和类胡萝卜素的吸光度分别为 0 .80 4和 0 .0 4 0 6 ;树莓种子油的皂化值为 1 92 ,对甲氧基苯胺值为 8.2 ,过氧化值为 5 .6 3mequiv/kg,粘度为 2 5 .2 m Ps。树莓种子油仅含有 α-,γ-和 δ-烷链维生素 E,树莓种子油的主要维生素 E为 γ-烷链维生素 ( 79% )和 α-烷链维生素 E( 2 0 % )。 | 梁俊 陈萍 B.Dave Oomah David Godfrey Giuseppe Mazza | 2002 | 西北农业学报2002，11，3： | 2 |
| 17 | 药物警戒汇总报告显示文摘药物警戒汇总报告是许多国家医疗管理部门要求企业递交的一系列药物警戒文件,包括欧盟的年度安全报告(ASR)及美国的研究新药物年度报告为临床信息汇总报告(IND)。上市后汇总报告包括欧盟、人用药物注册技术国际协调会议(ICH)的定期安全性信息更新报告(PSUR)及美国的定期药物不良事件报告(PADER)。药物警戒汇总报告将继续发展并成为信号检测及评估的较好手段之一。 | Tamara Mazza Carrie E Corboy 西安杨森药品安全部(译) | 2009 | 中国药物警戒2009，6，12： | 2 |
| 18 | 澳大利亚Danielle Mazza教授全科医疗案例分析--常见的母乳喂养问题显示文摘面对妇女健康领域的诸多问题,全科医生需要学习并掌握全面的、最新的妇女保健知识。澳大利亚Monash大学医学、护理和卫生科学部全科医学系主任丹尼尔·马扎(Danielle Mazza)教授为我们提供了一本很实用的学习用书,其主编的《Women's Health in General Practice》,涵盖了从少女至更年期妇女的整个生命周期中可能遇到的所有问题,包括月经问题、避孕、流产、不孕不育、孕前及产后保健、乳腺疾病、泌尿系疾病以及家庭暴力等。本书以病例解析的形式详细阐述了全科医生是如何对上述疾病进行诊断、鉴别诊断、治疗、评估和管理的。 | Danielle Mazza | 2015 | 中国全科医学2015，18，7： | 2 |
| 19 | Impact of number of run-off vessels on interwoven nitinol mesh stents patency in the femoropopliteal segment显示文摘Objective To evaluate the impact of run-off vessels number on the outcomes of Supera stent(Abbott Vascular,Santa Clara,Calif,USA)for treatment of femoropopliteal occlusive disease.Methods We retrospectively evaluated the medical records of 188 consecutive patients(mean age 68.2±9.6 years,100 males)undergone angiography and woven mesh stent implantation in femoral or popliteal arteries or both arterial segments,in our institution between January 12014 and January 12018.Target lesion revascularization and major adverse limb events at 12-month were evaluated comparing patients with 1-,2-or 3-run-off vessels in the foot.Results Interventional success was achieved in 100%.Stent implantation involved in the femoral site in 56 patients(30.3%),the femoropopliteal in 92 patients(48.9%)and the popliteal site in 40 patients(21.3%).A significant improvement of ankle-brachial index(0.29±0.6 vs.0.88±0.3,P<0.001)and Rutherford class(5.3±0.8 vs.0.7±1.9,P<0.01)were observed before discharge.The median follow-up duration was 12.3 months(inter quartile range:11.0 to 13.9).During the follow-up period,52 patients(27.6%)had clinical events.Primary patency at 12 months was 72.4%.The primary patency significantly increased when the runoff status.Comparing the number of events among patients with different number of run-off vessels,a significant difference(P<0.001)was observed for patients having one(24.0%)and two run-off vessels(15.0%).Conclusions The outcomes of Supera stent in femoropopliteal occlusive disease depend strictly on the number of run-off vessels. | Gianluca Rigatelli Marco Zuin Fabio Dell’Avvocata Dobrin Vassilev Stefano Barison Sabrina Osti Alberto Mazza Alberto Sacco | 2020 | Journal of Geriatric Cardiology2020，17，9： | 2 |
| 20 | The Innovative City in History显示文摘 | Mazza Luigi | 2001 | International Journal of Urban and Regional Research2001，，4： | 1 |
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