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| 1 | Prognostic value of site-specific metastases in pancreatic adenocarcinoma: A Surveillance Epidemiology and End Results database analysis显示文摘AIM To evaluate the prognostic value of site-specific metastases among patients with metastatic pancreaticc arcinoma registered within the Surveillance, Epidemiology and End Results(SEER) database.METHODS SEER database(2010-2013) has been queried through SEER*Stat program to determine the presentation, treatment outcomes and prognostic outcomes of metastatic pancreatic adenocarcinoma according to the site of metastasis. In this study, metastatic pancreatic adenocarcinoma patients were classified according to the site of metastases(liver, lung, bone, brain and distant lymph nodes). We utilized chi-square test to compare the clinicopathological characteristics among different sites of metastases. We used Kaplan-Meier analysis and log-rank testing for survival comparisons. We employed Cox proportional model to perform multivariate analyses of the patient population; and accordingly hazard ratios with corresponding 95%CI were generated. Statistical significance was considered if a two-tailed P value < 0.05 was achieved. RESULTS A total of 13233 patients with stage Ⅳ pancreatic cancer and known sites of distant metastases were identified in the period from 2010-2013 and they were included into the current analysis. Patients with isolated distant nodal involvement or lung metastases have better overall and pancreatic cancer-specific survival compared to patients with isolated liver metastases(for overall survival: lung vs liver metastases: P < 0.0001; distant nodal vs liver metastases: P < 0.0001)(for pancreatic cancer-specific survival: lung vs liver metastases: P < 0.0001; distant nodal vs liver metastases: P < 0.0001). Multivariate analysis revealed that age < 65 years, white race, being married, female gender; surgery to the primary tumor and surgery to the metastatic disease were associated with better overall survival and pancreatic cancer-specific survival.CONCLUSION Pancreatic adenocarcinoma patients with isolated liver metastases have worse outcomes compared to patients with isolated lung or distant nodal metastases. Further research is needed to identify the highly selected subset of patients who may benefit from local treatment of the primary tumor and/or metastatic disease. | Hani Oweira Ulf Petrausch Daniel Helbling Jan Schmidt Meinrad Mannhart Arianeb Mehrabi Othmar Schob Anwar Giryes Michael Decker Omar Abdel-Rahman | 2017 | World Journal of Gastroenterology2017,23,10: | 13 |
| 2 | Incidence trends and survival prediction of hepatoblastoma in children:a population-based study显示文摘Background:Hepatoblastoma is a rare disease that nevertheless accounts for the majority of liver malignancies in children.Due to limited epidemiological data,therapy for hepatoblastoma tends to be individualized.This study aimed to evaluate incidence trends of hepatoblastoma and to develop a nomogram to predict the survival of children with newly diagnosed hepatoblastoma on a population-based level.Methods:Individuals up to 18 years of age with hepatoblastoma recorded in 18 registries of the Surveillance,Epi-demiology,and End Results(SEER)database between 2004 and 2015 were examined.Joinpoint regression analyses were applied to assess incidence trends in annual percentage change(APC).Multivariable Cox regression was used to identify factors associated with overall survival(OS).A nomogram was constructed to predict OS in individual cases based on independent predictors.Concordance index(C-index)and calibration curves were used to evaluate predic-tive performance.Results:Between 2004 and 2015,hepatoblastoma incidence increased significantly(APC,2.2%;95%confidence interval[CI]0.5%to 3.8%,P<0.05).In particular,this increase was observed among 2-to 4-year-old patients,males,and African-Americans.The 5-and 10-year OS rates were 81.5%and 81.0%,respectively.Age of 2 to 4 years,Afri-can-American ethnicity,and no surgery were independent predictors for short OS.Distant disease at presentation was found not to be an independent factor of survival.The nomogram had a C-index of 0.79(95%CI 0.74-0.84)with appropriate calibration curve fitting.Conclusions:We constructed a nomogram that integrates common factors associated with survival for hepatoblas-toma patients.It provides accurate prognostic prediction for children with hepatoblastoma. | Jincheng Feng Georgios Polychronidis Ulrike Heger Giovanni Frongia Arianeb Mehrabi Katrin Hoffmann | 2019 | Cancer Communications2019,39,1: | 10 |
| 3 | CuO nanoparticles:An efficient and recyclable nanocatalyst for the rapid and green synthesis of 3,4-dihydropyrano[c]chromenes显示文摘Copper oxide nanoparticles showed excellent catalytic activity through three-component condensation reaction of aldehydes, malononitrile,and 4-hydroxycoumarin for the synthesis of 3,4-dihyropyrano[c]chromenes in water medium in excellent yields and very short reaction times. | Hossein Mehrabi Maryam Kazemi-Mireki | 2011 | Chinese Chemical Letters2011,22,12: | 4 |
| 4 | A systematic review and meta-analysis of laparoscopic versus open distal pancreatectomy for benign and malignant lesions of the pancreas: It’s time to randomize显示文摘 | Arianeb Mehrabi Mohammadreza Hafezi Jalal Arvin Majid Esmaeilzadeh Camelia Garoussi Golnaz Emami Julia K?ssler-Ebs Beat Peter Müller-Stich Markus W. Büchler Thilo Hackert Markus K. Diener | 2014 | Surgery2014,,: | 4 |
| 5 | Hepatocellular Carcinoma: Current Management and Perspectives for the Future显示文摘 | Nuh N. Rahbari Arianeb Mehrabi Nathan M. Mollberg Sascha A. Müller Moritz Koch Markus W. Büchler Jürgen Weitz | 2011 | Annals of Surgery2011,,3: | 3 |
| 6 | Current concepts in transplant surgery: liver transplantation today显示文摘 | A. Mehrabi H. Fonouni S. A. Müller J. Schmidt | 2008 | Langenbeck’s Archives of Surgery2008,,3: | 2 |
| 7 | Reconfigurable manufacturing systems: Key to future manufacturing显示文摘 | M. G. Mehrabi A. G. Ulsoy Y. Koren | 2000 | Journal of Intelligent Manufacturing2000,,4: | 2 |
| 8 | The safety and efficacy of PCNL with supracostal approach in the treatment of renal stones显示文摘 | Mousavi-Bahar SH Mehrabi S Moslemi MK | 2011 | Int Urol Nephrol2011,43,4: | 1 |
| 9 | Unified finite difference formula- tion for free vibration of cables显示文摘 | Mehrabi A B Tabatabai H | 2014 | Journal of Structural En- gineering2014,124,11: | 1 |
| 10 | Soy consumption, markers of inflammation, and endothelial function: a cross-over study in postmenopausal women with the metabolic syndrome 显示文摘 | AZADBAKHT L KIMIAGAR M MEHRABI Y | 2007 | Diabetes Care2007,30,4: | 1 |
| 11 | Circulatory and re spiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004,21,2: | 1 |
| 12 | Trends and Perspectives in Flexible and Recon Figurable Manufacturing Systems: Key to Future Manufacturing 显示文摘 | M G Mehrabi | 2002 | Journal of Intelligent Manufacturing2002,13,2: | 1 |
| 13 | Dietary patterns and markers of systemic inflammation among Iranian women 显示文摘 | Esmaillzadeh A Kimiagar M Mehrabi Y | 2007 | J Nutr2007,137,4: | 1 |
| 14 | Mitogen-activated protein kinase pathways and fungal pathogenesis显示文摘 | Zhao X H Mehrabi R Xu J R et ol | 2007 | Euraryotic Cell2007,6,10: | 1 |
| 15 | Reconfigurable manufacturing systems and their enabling technologies显示文摘 | MEHRABI M G ULSOY A G KOREN Y | 2000 | International Journal of Manufacturing Technology and Management2000,1,1: | 1 |
| 16 | Role of hydrogen peroxide during the interaction between the hemibiotrophic Fungal pathogen Septoria tritici and wheat显示文摘 | Shetty N P Mehrabi R Lfitken H | 2007 | New Phytolog2007,174,3: | 1 |
| 17 | Percutaneous nephrolithotomy complications in 671 consecutive patients:a single-centerexperience显示文摘 | Mousavi-Bahar SH Mehrabi S Moslemi MK | 2011 | Urol J2011,8,4: | 1 |
| 18 | Primary malignant hepa tie epithelioid hemangioendothelioma:a comprehensive review of the literaturewith emphasis on the surgical therapy显示文摘 | Mehrabi A Kashfi A Fonouni H | 2006 | Cancer2006,107,9: | 1 |
| 19 | Surgical treatment of primary hepatic epithelioid hemangioendothelioma显示文摘 | Mehrabi A Kashfi A Schemmer P | | 0,,1: | 1 |
| 20 | Maximizing data collection throughput on a path in energy harvesting sensor networks using a mobile sink显示文摘 | Mehrabi A Kim K | 2016 | IEEE Transactions on Mobile Computing2016,,: | 1 |