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| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | 2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction显示文摘 | Jeffrey L. Anderson Cynthia D. Adams Elliott M. Antman Charles R. Bridges Robert M. Califf Donald E. Casey William E. Chavey Francis M. Fesmire Judith S. Hochman Thomas N. Levin A. Michael Lincoff Eric D. Peterson Pierre Theroux Nanette K. Wenger R. Scott | 2013 | Journal of the American College of Cardiology2013，，23： | 2 |
| 3 | Marine habitats: loss and gain, mitigation and compensation显示文摘 | Michael Elliott Nicholas D. Cutts | 2004 | Marine Pollution Bulletin2004，，9： | 2 |
| 4 | Detection of Myocardial Damage in Patients With Sarcoidosis显示文摘 | Manesh R. Patel Peter J. Cawley John F. Heitner Igor Klem Michele A. Parker Wael A. Jaroudi Trip J. Meine James B. White Michael D. Elliott Han W. Kim Robert M. Judd Raymond J. Kim | 2009 | Circulation2009，，： | 2 |
| 5 | Predicting Survival in Pulmonary Arterial Hypertension: Insights From the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL)显示文摘 | Raymond L. Benza Dave P. Miller Mardi Gomberg-Maitland Robert P. Frantz Aimee J. Foreman Christopher S. Coffey Adaani Frost Robyn J. Barst David B. Badesch C. Gregory Elliott Theodore G. Liou Michael D. McGoon | 2010 | Circulation2010，，2： | 2 |
| 6 | Metabolic Modulator Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy显示文摘 | Khalid Abozguia Perry Elliott William McKenna Thanh Trung Phan Ganesh Nallur-Shivu Ibrar Ahmed Abdul R. Maher Kulvinder Kaur Jenny Taylor Anke Henning Houman Ashrafian Hugh Watkins Michael Frenneaux | 2010 | Circulation2010，，16： | 2 |
| 7 | Updated Clinical Classification of Pulmonary Hypertension显示文摘 | Gérald Simonneau Ivan M. Robbins Maurice Beghetti Richard N. Channick Marion Delcroix Christopher P. Denton C. Gregory Elliott Sean P. Gaine Mark T. Gladwin Zhi-Cheng Jing Michael J. Krowka David Langleben Norifumi Nakanishi Rogério Souza | 2009 | Journal of the American College of Cardiology2009，，1： | 1 |
| 8 | 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction显示文摘 | Elliott M. Antman Mary Hand Paul W. Armstrong Eric R. Bates Lee A. Green Lakshmi K. Halasyamani Judith S. Hochman Harlan M. Krumholz Gervasio A. Lamas Charles J. Mullany David L. Pearle Michael A. Sloan Sidney C. Smith | 2008 | Journal of the American College of Cardiology2008，，2： | 1 |
| 9 | Performance of Delayed-Enhancement Magnetic Resonance Imaging With Gadoversetamide Contrast for the Detection and Assessment of Myocardial Infarction: An International, Multicenter, Double-Blinded, Randomized Trial显示文摘 | Raymond J. Kim Timothy S.E. Albert James H. Wible Michael D. Elliott John C. Allen Jennifer C. Lee Michele Parker Alicia Napoli Robert M. Judd | 2008 | Circulation2008，，5： | 1 |
| 10 | The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1,matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes显示文摘 | Sarah Elliott Ezra Hays Michael Mayor | 2003 | Arthritis Res Ther2003，5，5： | 1 |
| 11 | Adoptive transfer of effector CD8^sup +^ T cells derived from central memory cells establishes persistent T cell memory in primates显示文摘 | Berger Carolina Jensen Michael C Lansdorp Peter M Gough Mike Elliott Carole Riddell Stanley R | 2008 | Journal of Clinical Investigation2008，，1： | 1 |
| 12 | Interventions for hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: a systematic review of randomized controlled trials显示文摘 | Michael M Elliott EJ Craig JC | 2009 | Am J Kidney Dis2009，53，： | 1 |
| 13 | Schiflett Potential contributions of rough sets data analysis to training evaluations显示文摘 | DAWN L RIDDLE MICHAEL D COOVERT LINDA R ELLIOTT etal | 2003 | Military Psychology2003，15，： | 1 |
| 14 | Predicting Survival in Pulmonary Arterial Hypertension: Insights From the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL)显示文摘 | Raymond L. Benza Dave P. Miller Mardi Gomberg-Maitland Robert P. Frantz Aimee J. Foreman Christopher S. Coffey Adaani Frost Robyn J. Barst David B. Badesch C. Gregory Elliott Theodore G. Liou Michael D. McGoon | 2010 | Circulation2010，，2： | 1 |
| 15 | Long-term follow-up of endoscopically treated upper urinary tract transitional cell carcinoma显示文摘 | Daniel S. Elliott Michael L. Blute David E. Patterson Erik J. Bergstralh Joseph W. Segura | 1996 | Urology1996，，： | 1 |
| 16 | 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction显示文摘 | Elliott M. Antman Mary Hand Paul W. Armstrong Eric R. Bates Lee A. Green Lakshmi K. Halasyamani Judith S. Hochman Harlan M. Krumholz Gervasio A. Lamas Charles J. Mullany David L. Pearle Michael A. Sloan Sidney C. Smith | 2008 | Journal of the American College of Cardiology2008，，2： | 1 |
| 17 | Contagion or Competition: The Case of Going Concern Audit Opinions for Real Estate Development Firms显示文摘 | Elliott R Stephen Mark Schaub Michael J Highfield | 2006 | Journal of Real Estate Finance and Economics2006，32，4： | 1 |
| 18 | Abciximab Improves Both Epicardial Flow and Myocardial Reperfusion in ST-Elevation Myocardial Infarction: Observations from the TIMI 14 Trial显示文摘 | James A. de Lemos Elliott M. Antman C. Michael Gibson Carolyn H. McCabe Robert P. Giugliano Sabina A. Murphy Stephanie A. Coulter Keaven Anderson Joel Scherer Martin J. Frey R. Van der Wieken Frans Van de Werf Eugene Braunwald | 2000 | Circulation: Journal of the American Heart Association2000，，3： | 1 |
| 19 | The Refractive Status and Vision Profile: Evaluation of psychometric properties and comparison of Rasch and summated Likert-scaling显示文摘 | Estibaliz Garamendi Konrad Pesudovs Michael J. Stevens David B. Elliott | 2005 | Vision Research2005，，8： | 1 |
| 20 | Management of penetrating colon and rectal injuries in the pediatric patient显示文摘 | Elliott R Michael L Martin S | 2004 | Dis Colon Rectum2004，47，： | 1 |
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