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| 1 | Two-year clinical outcome of denosumab treatment alone and in combination with teriparatide in Japanese treatment-naive postmenopausal osteoporotic women显示文摘This randomized prospective study aimed to evaluate the clinical outcome of denosumab treatment alone and in combination with teriparatide in treatment-naive postmenopausal Japanese female patients with osteoporosis. Thirty patients were randomly assigned to two groups:(1) denosumab group(denosumab alone, n=13); and(2) combination group(denosumab+teriparatide, n=17). Serum bone-specific alkaline phosphatase(BAP), serum tartrate-resistant acid phosphatase(TRACP)-5b, urinary cross-linked N-terminal telopeptides of type I collagen(NTX), and bone mineral density(BMD) of L1–4 lumbar vertebrae(L-BMD)and bilateral total hips(H-BMD) were determined at the first visit and at various time points up to 24 months post-treatment to determine percentage changes. Serum TRACP-5b and urinary NTX were equally suppressed in both groups and maintained at low levels, with slight increases at 12, 18 and 24 months. BAP was significantly decreased in both groups from 4 to 24 months, with significant differences between the groups at 4, 8 and 15 months(P<0.05). L-BMD was significantly increased at most time points in both groups, with a significant difference between the combination group and denosumab group at 24 months(17.2% increase versus 9.6% increase; P<0.05). There was no significant difference in H-BMD between the two groups, although the levels tended to be higher in the combination group than in the denosumab group(9.5% increase versus 5.6% increase). These findings suggest that denosumab+teriparatide combination therapy may represent an important treatment for primary osteoporotic patients at high risk of vertebral fracture. | Yukio Nakamura Takako Suzuki Mikio Kamimura Shota Ikegami Kohei Murakami Shigeharu Uchiyama Akira Taguchi Hiroyuki Kato | 2017 | Bone Research2017，5，2： | 2 |
| 2 | HITTM Cells-high-efficiency Crystalline Si Cells with Novel Structure显示文摘 | Mikio Taguchi Kunihiro Kawamoto Sadaji Tsuge | 2000 | Pro Photovolt:Res Appl2000，8，5： | 1 |
| 3 | Mode of onset of ventricular fibrillation in patients with Brugada syndrome detected by implantable cardioverter defibrillator therapy显示文摘 | Mikio Kakishita Takashi Kurita Kiyotaka Matsuo Atsushi Taguchi Kazuhiro Suyama Wataru Shimizu Naohiko Aihara Shiro Kamakura Fumio Yamamoto Junjiro Kobayashi Yoshio Kosakai Tohru Ohe | 2000 | Journal of the American College of Cardiology2000，，5： | 1 |
| 4 | Development status of high-efficiency HIT solar ceils 显示文摘 | Mishima Takahiro Taguchi Mikio Hitoshi | 2011 | Solar Energy Materials and Solar Cells2011，95，1： | 1 |
| 5 | Twenty-two percent efficiency HIT solar cell显示文摘 | Tsunomura Yasufumi Yoshimine Yukihiro Taguchi Mikio | 2008 | So- lar Energy Mater Solar Cells2008，93，67： | 1 |
| 6 | Development status of high-efficiency HIT solar cells 显示文摘 | Mishima Takahiro Taguchi Mikio Sakata Hitoshi | 2011 | Solar Energy Materials and Solar Cells2011，95，1： | 1 |
| 7 | Development status of high-efficiency HIT solar cells显示文摘 | Takahiro Mishima Mikio Taguchi Hitoshi Sakata | 2011 | Solar Energy Materials&Solar Cells2011，95，1： | 1 |
| 8 | HITTM cells-highefficiency crystalline Si cells with novel structure显示文摘 | Mikio Taguchi Kunihiro Kawamoto | 2000 | Prog Photovolt:Res Appl2000，，8： | 1 |
| 9 | Development status of high-efficiency HIT solar cells显示文摘 | Takahiro Mishima Mikio Taguchi Hitoshi Sakata Eiji Maruyama | 2010 | Solar Energy Materials and Solar Cells2010，，1： | 1 |
| 10 | High growth - rate fabrication of micro - crystalline by Helicon wave plasma CVD显示文摘 | Masao Isomura Mikio Taguchi | 2001 | Sol Energy Mater Sol Cells2001，66，： | 1 |
| 11 | HIT IM cells-high-efficiency crystalline Si cells with novel structure显示文摘 | Mikio Taguchi Kunihiro Kawamoto Sadaji Tsuge | 2000 | Progress in Photovoltaics: Research andAl:licafions2000，，： | 1 |
| 12 | 40年来日本稻作回顾显示文摘稻作是日本农业最主要的构成要素。长久以来日本一直以稻米为主食,所以对日本来说稻作具有特殊的意义。但是由于近几十年来稻米消费的大量减少,日本于20年前开始限制稻米生产以克服稻米过剩所带来的问题。虽然稻作对日本来说具有特殊的意义,稻米确实也是日本人的主食品,但约30年前日本的稻米生产就能满足国内的需求。在此之前由于稻米生产不足,粮食短缺,日本不断地努力改善稻作栽培条件。由于现在年轻的日本人不象他们的前辈那样喜欢稻米,稻米消费大量减少。但是,可以相信随着时间的推移。日本的青年人会发现稻米的价值。 | Mikio TAGUCHI 黄育民 | 1991 | 福建稻麦科技1991，0，2： | 0 |
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