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| 1 | XA23 Is an Executor R Protein and Confers Broad-Spectrum Disease Resistance in Rice显示文摘 | Chunlian Wang Xiaoping Zhang Yinglun Fan Ying Gao Qinlong Zhu Chongke Zheng Tengfei Qin Yanqiang Li Jinying Che Mingwei Zhang Bing Yang Yaoguang Liu Kaijun Zhao | 2015 | Molecular Plant2015，8，2： | 55 |
| 2 | The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China. | Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao | 2016 | Translational Neurodegeneration2016，5，1： | 23 |
| 3 | Slope stability analysis under seismic load by vector sum analysis method显示文摘The vibration characteristics and dynamic responses of rock and soil under seismic load can be estimated with dynamic finite element method(DFEM).Combining with the DFEM,the vector sum analysis method(VSAM) is employed in seismic stability analysis of a slope in this paper.Different from other conventional methods,the VSAM is proposed based on the vector characteristic of force and current stress state of the slope.The dynamic stress state of the slope at any moment under seismic load can be obtained by the DFEM,thus the factor of safety of the slope at any moment during earthquake can be easily obtained with the VSAM in consideration of the DFEM.Then,the global stability of the slope can be estimated on the basis of time-history curve of factor of safety and reliability theory.The VSAM is applied to a homogeneous slope under seismic load.The factor of safety of the slope is 1.30 under gravity only and the dynamic factor of safety under seismic load is 1.21.The calculating results show that the dynamic characteristics and stability state of the slope with input ground motion can be actually analyzed.It is believed that the VSAM is a feasible and practical approach to estimate the dynamic stability of slopes under seismic load. | Mingwei Guo Xiurun Ge Shuilin Wang | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，3： | 14 |
| 4 | Superabsorbent Fibers for Comfortable Disposable Medical Protective Clothing显示文摘Disposable medical protective clothing for 2019-nCoV mainly consists of stacked layers with nanopore films,polymer coated nonwoven fabrics and melt-blown nonwoven fabrics against anti-microbial and anti-liquid penetration.However,such structures lack moisture permeability and breathability leading to an uncomfortable,stuffy wearing experience.Here,we propose a novel medical protective clothing material with a superabsorbent layer to enhance moisture absorption.Poly(acrylic acid-co-acrylamide)/polyvinyl alcohol superabsorbent fibers(PAAAM/PVA fibers)were prepared via wet spinning.And the superabsorbent composite layer was stacked from PAAAM/PVA fibers,bamboo pulp fibers(BPF)and ethylene-propyl-ene side by side fibers(ESF).The novel disposable medical protective composite fabric was obtained through gluing the superabsorbent layer to the inner surface of strong antistatic polypropylene nonwoven fabric.The resultant composite fabric possesses excellent absorption and retention capacity for sweat,up to 12.3 g/g and 63.8%,and a maximum hygroscopic rate of 1.04 g/h,higher than that of the conventional material(only 0.53 g/h).The moisture permeability of the novel material reached 12,638.5 g/(m^(2) d),which was 307.6%of the conventional material.The novel material can effectively reduce the humidity inside the protective clothing and significantly improve the comfort of medical staff. | Lin Yang Hong Liu Shuai Ding Jiawei Wu Yan Zhang Zhongzhen Wang Lili Wei Mingwei Tian Guangming Tao | 2020 | Advanced Fiber Materials2020，2，3： | 11 |
| 5 | Hydroisomerization performance of platinum supported on ZSM-22/ZSM-23 intergrowth zeolite catalyst显示文摘Hydroisomerization catalysts Pt/ZSM-22,Pt/ZSM-23,and Pt/ZSM-22/ZSM-23 were prepared by supporting Pt on ZSM-22,ZSM-23,and intergrowth zeolite ZSM-22/ZSM-23,respectively.The typical physicochemical properties of these catalysts were characterized by X-Ray Diffraction(XRD),N2 absorption-desorption,Pyridine-Fourier Transform Infrared(Py-FTIR),Transmission Electron Microscopy(TEM),X-Ray Fluorescence(XRF),Scanning Electron Microscopy(SEM) and NH3-Temperature Programmed Desorption(NH3-TPD),and the performance of these catalysts in n-dodecane hydroisomerization was evaluated in a continuous down-flow fixed bed with a stainless steel tubular reactor.The characterization results indicated that the intergrowth zeolite ZSM-22/ZSM-23 possessed the dual structure of ZSM-22 and ZSM-23,and the catalyst Pt/ZSM-22/ZSM-23 had similar pores and weak acidity to Pt/ZSM-22 and Pt/ZSM-23 catalysts.Moreover,Pt/ZSM-22/ZSM-23 catalyst showed a high selectivity in hydroisomerization of long chain n-alkanes to mono-branched isomers.The evaluation results for n-dodecane hydroisomerization indicated that the activity of Pt/ZSM-22/ZSM-23 was the lowest,while the hydroisomerization selectivity was the highest among the three catalysts.The maximum yield of i-dodecane product was 68.3% over Pt/ZSM-22/ZSM-23 at 320 oC. | Chi Kebin Zhao Zhen Tian Zhijian Hu Sheng Yan Lijun Li Tianshu Wang Bingchun Meng Xiangbin Gao Shanbin Tan Mingwei Liu Yanfeng | 2013 | Petroleum Science2013，10，2： | 8 |
| 6 | A fundamental theorem for eco-environmental surface modelling and its applications显示文摘We propose a fundamental theorem for eco-environmental surface modelling(FTEEM) in order to apply it into the fields of ecology and environmental science more easily after the fundamental theorem for Earth’s surface system modeling(FTESM). The Beijing-Tianjin-Hebei(BTH) region is taken as a case area to conduct empirical studies of algorithms for spatial upscaling, spatial downscaling, spatial interpolation, data fusion and model-data assimilation, which are based on high accuracy surface modelling(HASM), corresponding with corollaries of FTEEM. The case studies demonstrate how eco-environmental surface modelling is substantially improved when both extrinsic and intrinsic information are used along with an appropriate method of HASM. Compared with classic algorithms, the HASM-based algorithm for spatial upscaling reduced the root-meansquare error of the BTH elevation surface by 9 m. The HASM-based algorithm for spatial downscaling reduced the relative error of future scenarios of annual mean temperature by 16%. The HASM-based algorithm for spatial interpolation reduced the relative error of change trend of annual mean precipitation by 0.2%. The HASM-based algorithm for data fusion reduced the relative error of change trend of annual mean temperature by 70%. The HASM-based algorithm for model-data assimilation reduced the relative error of carbon stocks by 40%. We propose five theoretical challenges and three application problems of HASM that need to be addressed to improve FTEEM. | Tianxiang YUE Na ZHAO Yu LIU Yifu WANG Bin ZHANG Zhengping DU Zemeng FAN Wenjiao SHI Chuanfa CHEN Mingwei ZHAO Dunjiang SONG Shihai WANG Yinjun SONG Changqing YAN Qiquan LI Xiaofang SUN Lili ZHANG Yongzhong TIAN Wei WANG Ying’an WANG Shengnan MA Hongsheng HUANG Yimin LU Qing WANG Chenliang WANG Yuzhu WANG Ming LU Wei ZHOU Yi LIU Xiaozhe YIN Zong WANG Zhengyi BAO Miaomiao ZHAO Yapeng ZHAO Yimeng JIAO Ufra NASEER Bin FAN Saibo LI Yang YANG John PWILSON | 2020 | Science China Earth Sciences2020，63，8： | 7 |
| 7 | Protonation induced high-T_c phases in iron-based superconductors evidenced by NMR and magnetization measurements显示文摘Chemical substitution during growth is a well-established method to manipulate electronic states of quantum materials, and leads to rich spectra of phase diagrams in cuprate and iron-based superconductors. Here we report a novel and generic strategy to achieve nonvolatile electron doping in series of(i.e.11 and 122 structures) Fe-based superconductors by ionic liquid gating induced protonation at room temperature. Accumulation of protons in bulk compounds induces superconductivity in the parent compounds, and enhances the Tclargely in some superconducting ones. Furthermore, the existence of proton in the lattice enables the first proton nuclear magnetic resonance(NMR) study to probe directly superconductivity. Using Fe S as a model system, our NMR study reveals an emergent high-Tcphase with no coherence peak which is hard to measure by NMR with other isotopes. This novel electric-fieldinduced proton evolution opens up an avenue for manipulation of competing electronic states(e.g.Mott insulators), and may provide an innovative way for a broad perspective of NMR measurements with greatly enhanced detecting resolution. | Yi Cui Gehui Zhang Haobo Li Hai Lin Xiyu Zhu Hai-Hu Wen Guoqing Wang Jinzhao Sun Mingwei Ma Yuan Li Dongliang Gong Tao Xie Yanhong Gu Shiliang Lie Huiqian Luo Pu Yu Weiqiang Yu | 2018 | Science Bulletin2018，63，1： | 7 |
| 8 | Parameter Group Optimization by Combining CUBE with Surface Filtering and Its Application显示文摘Shallow water multi-beam echo sounders(MBESs)are characterized by their high resolution and high density,and MBES data processing is a hotspot in modern marine surveying.The Combined Uncertainty and Bathymetry Estimator(CUBE)is the mainstream MBES data processing algorithm,although little is known about its core theories and parameters.In this paper,the basic principle,mathematical model,key parameters,and main processing steps of CUBE are described systematically.A parameter group optimization method that combines CUBE with a surface filter is established.Additionally,an example is given that shows the steps for parameter group optimization,including selection of a typical area,parameter group testing,and comparative analysis,and the method is then applied to shallow water MBES data processing.The results show that the method can improve the accuracy and efficiency of automatic data processing effectively,and it is thus of engineering application value. | Dineng ZHAO Ziyin WU Jieqiong ZHOU Mingwei WANG Zhihao LIU Jiabiao LI | 2020 | Journal of Geodesy and Geoinformation Science2020，3，2： | 7 |
| 9 | N-Methyl-D-Aspartate Receptor and Apoptosis in Alzheimer's Disease and Multiinfarct Dementia显示文摘 | Marong Fang Jicheng Li S.C. Tiu Lihong Zhang Mingwei Wang David T. Yew | 2005 | 中国生物学文摘2005，19，11： | 6 |
| 10 | Multi-robot cooperative localization based on autonomous motion state estimation and laser data interaction显示文摘Multi-robot cooperative localization is an important research topic in mobile robotics. This paper mainly studies the problem of cooperative localization based on environment information interaction in unknown complex environment. Considering the effiect of robot motion state on the cooperative localization, we present an algorithm for adaptive selecting periods of the cooperative localization based on autonomous motion state estimation. In order to avoid equipping an extra localization marker on the robot which is needed for direct observation between robots, and to make full use of the interactive information between robots in the same scene, a method for obtaining multi-robot observations based on MbICP algorithm is proposed, which makes multirobot cooperative localization using EKF feasible and reliable in cluttered environment. Experiment results with the Pioneer 3-DX robots and data analysis show the method's validity and practicability. | ZHUANG Yan, GU MingWei, WANG Wei & YU HaiYang Research Center of Information and Control, Dalian University of Technology, Dalian 106024, China | 2010 | Science China(Information Sciences)2010，53，11： | 6 |
| 11 | miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor显示文摘Embryo implantation is a crucial step in mammalian reproduction.However,little is known regarding the physiological roles of microRNAs in the regulation of embryo implantation.Here we show that a minimum uterine expression of miR-181 is essential for the onset of embryo implantation.Both transient and prolonged transgenic expression of miR-181 led to impaired implantation,which can be rescued by exogenous administration of leukemia inhibitory factor(LIF).Mechanistically,miR-181 is able to directly target LIF and downregulate LIF expression,thereby inhibiting embryo implantation.We also show that miR-181 expression is regu-lated by the transcriptional factor Emx2,and the Emx2–miR-181 axis plays an importantrole in regulating embryo implantation.Taken together,these results reveal a novel function of miR-181 in embryo implantation through the regulation of LIF,and also indicate a potential link between miR-181 dysregulation and human embryo implantation defects. | Bo Chu Liangwen Zhong Shuang Dou Jun Wang Jianmin Li Mingwei Wang Qinghua Shi Yide Mei Mian Wu | 2015 | Journal of Molecular Cell Biology2015，7，1： | 5 |
| 12 | Effect of the degree of milling on the physicochemical properties,pasting properties and in vitro digestibility of Simiao rice显示文摘Simiao rice is a variety of long-grain Indica rice popular in South China.However,researches on the milling technology of Simiao rice are limited.The effect of different degrees of milling(DOMs)of Simiao rice(0-12%)were evaluated in terms of the physicochemical properties and in vitro starch digestibility of the rice.The results showed that,as the DOM increased from 0 to 12%,the head rice yield(HRY)and the content of protein,lipid,dietary fiber,vitamin B1,vitamin E and niacin nonlinearly decreased,while the content of total starch and amylose and paste viscosity parameters nonlinearly increased.The differences in chemical constituents between the brown and milled Simiao rice with different DOMs lead to the variation in their pasting properties and in vitro digestibility.Because of lower content of slowly digestible starch(SDS)and resistant starch(RS),milled Simiao rice exhibited greater digestibility and a higher estimated glycaemic index(EGI).The EGI of Simiao rice ranged from 77.98 to 85.55,and remained almost constant(approximately 84)when the DOM was above 4%.Correlation analysis indicated that the EGI had strong negative correlations with lipid,protein,dietary fiber and RS,but a positive correlation with amylose.These results provide theoretical guidance for the production of Simiao rice with desired physicochemical properties and digestibility by adjusting the DOM. | Zhiming Wang Mingwei Zhang Guang Liu Yuanyuan Deng Yan Zhang Xiaojun Tang Ping Li Zhencheng Wei | 2021 | Grain & Oil Science and Technology2021，4，2： | 5 |
| 13 | Atomistic Surface Passivation of CH_(3)NH_(3)PbI_(3) Perovskite Single Crystals for Highly Sensitive Coplanar-Structure X-Ray Detectors显示文摘Organic-inorganic halide perovskites(OIHPs)are recognized as the promising next-generation X-ray detection materials.However,the device performance is largely limited by the ion migration issue of OIHPs.Here,we reported a simple atomistic surface passivation strategy with methylammonium iodide(MAI)to remarkably increase the ion migration activation energy of CH_(3)NH_(3)PbI_(3)single crystals.The amount of MAI deposited on the crystal surface is finely regulated by a self-assemble process to effectively suppress the metallic lead defects,while not introducing extra mobile ions,which results in significantly improved dark current stability of the coplanar-structure devices under a large electric field of 100Vmm^(-1).The X-ray detectors hence exhibit a record-high sensitivity above 700,000μC Gy^(-1)_(air) cm^(-2)under continuum X-ray irradiation with energy up to 50 keV,which enables an ultralow X-ray detection limit down to 1.5 nGy_(air)s^(-1).Our findings will allow for the dramatically reduced X-ray exposure of human bodies in medical imaging applications. | Yilong Song Liqi Li Weihui Bi Mingwei Hao Yifei Kang Anran Wang Zisheng Wang Hanming Li Xiaohui Li Yanjun Fang Deren Yang Qingfeng Dong | 2020 | Research2020，，1： | 5 |
| 14 | A machine learning-based algorithm used to estimate the physiological elongation of ocular axial length in myopic children显示文摘Background:Axial myopia is the most common type of myopia.However,due to the high incidence of myopia in Chinese children,few studies estimating the physiological elongation of the ocular axial length(AL),which does not cause myopia progression and differs from the non-physiological elongation of AL,have been conducted.The purpose of our study was to construct a machine learning(ML)-based model for estimating the physiological elongation of AL in a sample of Chinese school-aged myopic children.Methods:In total,1011 myopic children aged 6 to 18 years participated in this study.Cross-sectional datasets were used to optimize the ML algorithms.The input variables included age,sex,central corneal thickness(CCT),spherical equivalent refractive error(SER),mean K reading(K-mean),and white-to-white corneal diameter(WTW).The output variable was AL.A 5-fold cross-validation scheme was used to randomly divide all data into 5 groups,including 4 groups used as training data and one group used as validation data.Six types of ML algorithms were implemented in our models.The best-performing algorithm was applied to predict AL,and estimates of the physiological elongation of AL were obtained as the partial derivatives of AL_(predicted)-age curves based on an unchanged SER value with increasing age.Results:Among the six algorithms,the robust linear regression model was the best model for predicting AL,with a R^(2) value of 0.87 and relatively minimal averaged errors between the predicted AL and true AL.Based on the partial derivatives of the AL_(predicted)-age curves,the estimated physiological AL elongation varied from 0.010 to 0.116 mm/year in male subjects and 0.003 to 0.110 mm/year in female subjects and was influenced by age,SER and K-mean.According to the model,the physiological elongation of AL linearly decreased with increasing age and was negatively correlated with the SER and the K-mean.Conclusions:The physiological elongation of the AL is rarely recorded in clinical data in China.In cases of unavailable clinical dat,an ML algorithm could provide practitioners a reasonable model that can be used to estimate the physiological elongation of AL,which is espedally useful when monitoring myopia progression in orthokeratology lens wearers. | Tao Tang Zekuan Yu Qiong Xu Zisu Peng Yuzhuo Fan Kai Wang Qiushi Ren Jia Qu Mingwei Zhao | 2020 | Eye and Vision2020，7，1： | 4 |
| 15 | Binary glowworm swarm optimization for unit commitment显示文摘This paper proposes a new algorithm—binary glowworm swarm optimization(BGSO)to solve the unit commitment(UC)problem.After a certain quantity of initial feasible solutions is obtained by using the priority list and the decommitment of redundant unit,BGSO is applied to optimize the on/off state of the unit,and the Lambda-iteration method is adopted to solve the economic dispatch problem.In the iterative process,the solutions that do not satisfy all the constraints are adjusted by the correction method.Furthermore,different adjustment techniques such as conversion from cold start to hot start,decommitment of redundant unit,are adopted to avoid falling into local optimal solution and to keep the diversity of the feasible solutions.The proposed BGSO is tested on the power system in the range of 10–140 generating units for a 24-h scheduling period and compared to quantuminspired evolutionary algorithm(QEA),improved binary particle swarm optimization(IBPSO)and mixed integer programming(MIP).Simulated results distinctly show that BGSO is very competent in solving the UC problem in comparison to the previously reported algorithms. | Mingwei LI Xu WANG Yu GONG Yangyang LIU Chuanwen JIANG | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，4： | 4 |
| 16 | Applying resolved-scale linearly forced isotropic turbulence in rational subgrid-scale modeling显示文摘In previous attempts of rational subgrid-scale (SGS) modeling by employing the Kolmogorov equation of filtered (KEF) quantities, it was necessary to assume that the resolved-scale second-order structure function is stationary. Forced isotropic turbulence is often used as a framework for establishing and validating such SGS models based on stationary restrictions, for it generates statistical stationary samples. However, traditional forcing method at low wavenumbers cannot provide an analytic form of forcing term for a complete KEF in physical space, which has been illustrated to be essential in the modeling of such SGS models. Thus, an alternative forcing method giving an analytic forcing term in physical space is needed for rational SGS modeling. Giving an analytic linear driving term in physical space, linearly forced isotropic turbulence should be considered an ideal theoretical framework for rational SGS modeling. In this paper, we demonstrate the feasibility of establishing a rational SGS model with stationary restriction based on linearly forced isotropic turbulence. The performance of this rational SGS model is validated. We, therefore, propose the use of linearly forced isotropic turbulence as a complement to free-decaying isotropic turbulence and low-wavenumber forced isotropic turbulence for SGS model validations. | Chuhan Wang Mingwei Ge | 2019 | Acta Mechanica Sinica2019，35，3： | 3 |
| 17 | An Improved Filter of Progressive TIN Densification for LiD AR Point Cloud Data显示文摘Based on the classic filter of progressive triangulated irregular network(TIN) densification, an improved filter is proposed in this paper. In this method, we divide ground points into grids with certain size and select the lowest points in the grids to reconstruct TIN in the process of iteration. Compared with the classic filter of progressive TIN densification(PTD), the improved method can filter out attached objects, avoid the interference of low objects and obtain relatively smooth bare-earth. In addition, this proposed filter can reduce memory requirements and be more efficient in processing huge data volume. The experimental results show that the filtering accuracy and efficiency of this method is higher than that of the PTD method. | WANG Huan WANG Shugen CHEN Qi JIN Weihua SUN Mingwei | 2015 | Wuhan University Journal of Natural Sciences2015，20，4： | 3 |
| 18 | Grain size characteristics of surface sediment and its response to the dynamic sedimentary environment in Qiantang Estuary, China显示文摘The composition and grain size characteristics of sediment in estuarine and coastal environments provide important information on the material source, hydrodynamic environment, environmental events,etc. However, few studies have focused on the sediment characteristics of the entire Qiantang Estuary,particularly, on the correlation between hydrodynamics and sediment properties. Through systematic sampling of the surface sediment in a large area of the Qiantang Estuary, the spatial distribution characteristics of the surface sediment of the Qiantang Estuary, such as the grain size composition and particle size parameters, in different sections of the estuary area are analyzed. By comparing the particle size data of different estuaries, the similarities and differences of the particle size parameters of the Qiantang Estuary and other estuaries are compared and analyzed. According to the differences in the sediment composition, the distribution status of the particle size frequency curves and the morphological characteristics of the probability curves in the entire study area, the Qiantang Estuary is divided into 7 dynamic depositional areas: Fuchunjiang Hydropower Station-Fuyang, Fuyang-Qibao, Qibao-Cao’e River, Cao’e River-Zhapu, North Shore of Hangzhou Bay, middle part of Hangzhou Bay, and South Shore of Hangzhou Bay, which are different from the previous estuary segmentation system. The study area is divided into 13 dynamic depositional sub-regions using the Pejrup M triangle diagram. Combining the calculation results of the mathematical model and the Pejrup M triangle diagram, the relation between the dynamic deposition environment and the bottom shear stress is discussed. It is found that the spatial distribution of the bottom shear stress in the study area is in good agreement with the zoning of the dynamic sedimentary environment. | Shanshan Wang Cunhong Pan Dongfeng Xie Mingwei Xu Yuhan Yan Xinwen Li | 2022 | International Journal of Sediment Research2022，37，4： | 3 |
| 19 | Liquid droplet movement on horizontal surface with gradient surface energy显示文摘A surface with gradient surface energy was fabricated on a silicon wafer by using the chemical vapor deposition (CVD) technology with the dodecyltrichlorosilane (C12H25Cl3Si) vapor which was adsorbed chemically on the surface of the silicon wafer to form a self-assemble monolayer (ASM) and thus a gradient profile of wettability. The microscopic contours of the gradient surface were measured with Seiko SPA400 atom force microscope (AFM). And the surface wettability profile was characterized by the sessile drop method, measuring the contact angle of fine water droplets that lay on the gradient surface, to represent the distribution of the surface energy on the surface. Using a high-speed video imaging system, the motion of water droplet on the horizontal gradient surface was visualized and the transient velocity was measured under ambient condition. The experimental results show that the liquid droplets can be driven to move from hydrophobic side to hydrophilic side on the horizontal gradient surface and the velocity of droplet can reach up to 40 mm/s. In addition, the motion of the water droplet can be generally divided into two stages: an acceleration stage and a deceleration stage. The droplet presents a squirming movement on the surface with a lower peak velocity and a larger extent of deceleration motion. And the static advancing contact angle of the droplet is obviously larger than the dynamic advancing contact angle on the gradient energy surface. | LIAO Qiang WANG Hong ZHU Xun LI Mingwei | 2006 | Science China(Technological Sciences)2006，49，6： | 3 |
| 20 | Synthesis of O-(2-[^(18)F]fluoroethyl)-L-tyrosine and its biological evaluation in B16 melanoma-bearing mice as PET tracer for tumor imaging显示文摘O-(2-[18F]fluoroethyl) -L-tyrosine([18F]FET) ,a fluorine-18 labeled analogue of tyrosine,has been syn-thesized and biologically evaluated in tumor-bearing mice. The whole synthesis procedure is com-pleted within 50 min. The radiochemical yield is about 40%(no decay corrected) and radiochemical purity more than 97% after simplified solid phase extraction. [18F]FET shows rapid,high uptake and long retention in the tumor as well as low uptake in the brain. The ratios of tumor-to-muscle(T/M) and tumor-to-blood(T/B) of [18F]FET are similar to those of [18F]FDG,but the ratios of tumor-to-brain(T/Br) are 2-3 times higher than that of [18F]FDG. Autoradiography of [18F]FET demonstrates a remarkable accumulation in melanoma with high contrast. It appears to be a probable competitive candidate for melanoma imaging with PET. | WANG MingWei,YIN DuanZhi,LI ShiQiang & WANG YongXian Radiopharmaceutical Centre,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China | 2007 | Science China Chemistry2007，50，2： | 3 |
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