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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Interesting physical properties of the new spinel phase of Si《,3》N《,4》 and C《,3》N《,4》显示文摘 | Ouyang L Z and Ching W Y | 1999 | Physical Review Letters1999，83，： | 1 |
| 3 | Theoretical prediction of the structure and properties of cubic spinel nitrides显示文摘 | Mo S D Ouyang L Z | 2002 | Journal of the American Ceramic Society2002，85，： | 1 |
| 4 | Undetstanding PRRSV Infection in Porcine Lung Based on Genome-Wide Transcriptome Response Identified by Deep Sequencing显示文摘 | Xiao S Q Jia J Y Mo D L | 2010 | PLoS ONE2010，5，6： | 1 |
| 5 | Interesting physical properties of the new spinel phase of Si3 N4 and C3N4显示文摘 | MO S D OUYANG L CHING W Y | 1999 | Phys Rev Lett1999，83，24： | 1 |
| 6 | 查看详情显示文摘 | MO Y PEYERIMHOFF S D | | 0，，： | 1 |
| 7 | Geochemical investigation of Early Cretaceous igneous rocks along an east-west traverse throughout the central Lhasa Terrane, Tibet显示文摘 | Zhu D C Mo X X Niu Y L Zhao Z D Wang L Q Liu Y S Wu F Y | 2009 | Chem Geol2009，268，34： | 1 |
| 8 | Receiver gain function: the actu- al NMR receiver gain 显示文摘 | Mo H Harwood J S Raftery D | 2010 | Magn Reson Chem2010，48，3： | 1 |
| 9 | Electronic Structure of Normal, Inverse,and Partially Inverse Spinels in the MgAl2O4 System 显示文摘 | Mo S D Ching W Y | 1996 | Phys Rev B1996，54，16： | 1 |
| 10 | Structural transformation of carbon nanotubes to silicon carbide nanorods or microcrystals by the reaction with different silicon sources in rf induced CVD reactor显示文摘 | Mo Y H Shajaban M D Lee Y S | 2004 | Synthetic Met2004，140，7： | 1 |
| 11 | Interesting Physical Properties of the New Spinel Phase of Si3N4 and C3N4显示文摘 | Mo S D Ouyang L Z Ching W Y | 1999 | Physical Review Letters1999，83，： | 1 |
| 12 | Reduction of obesity,as induced by leptin,reverses endothelial dysfunction in obese (Lepob) mice显示文摘 | Bradford W Mo ZP Brooks-Asplund E Kim S Shoukas A Li D | 2000 | J Appl Physiol2000，89，： | 1 |
| 13 | Electronic and optical properties of three phases of titanium dioxide: rutile, anatase, and brookite显示文摘 | MO S D CHING W Y | 1995 | Physical Review B1995，51，13： | 1 |
| 14 | Understanding Prrsv infec- tion in porcine lung based on genome-wide transcrip- tome response identified by deep sequencing显示文摘 | Xiao S Jia J Mo D | 2010 | PLoS One2010，5，11： | 1 |
| 15 | Nickel-catalyzed propylene dimerization in organochloroaluminate ionic liq uids: control of the isomerization reaction显示文摘 | SOUZA R F D LEAL B C MO D S | 2007 | J Mol Catal A: Chem2007，272，12： | 1 |
| 16 | Undetstanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequendng显示文摘 | Xiao S Q Jia J Y Mo D L | 2010 | PLoS ONE2010，5，： | 1 |
| 17 | The 132 Ma ComeiBunbury large igneous province:Remnants identified in presentday southeastern Tibet and southwestern Australia显示文摘 | ZHU D C CHUNG S L MO X X | 2009 | Geology2009，37，7： | 1 |
| 18 | 显示文摘 | Mo S D Ching W Y | 1995 | Phys Rev B1995，51，13： | 1 |
| 19 | The NCEP/NCAR 40-yeax reanalysis project 显示文摘 | E Kalnay M Kanamitsu R Kistler WCollins D Deaven L Gandin M Iredell S Saha G White J Woollen Y Zhu M Chelliah W Ebisuzaki W Higgins J Janowiak KC Mo C Ropelewski J Wang A Leetmaa R Reynolds R Jenne D Joseph | 1996 | Bulletin of the American Meteorological Society (S0003-0007)1996，77，3： | 1 |
| 20 | Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling显示文摘 | Xiao S Q Mo D L Wang Q W | 2010 | BMC Genomics2010，11，： | 1 |
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