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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Atomic bonding of precipitate and phase transformation of Al-Cu-Mg alloy 显示文摘 | CAO Y J HOU X H MO Q F | 2007 | J Alloys Compd2007，441，： | 1 |
| 3 | Effect of the Woods-Saxon nuclear distribution on the chiral magnetic field in Relativ- istic Heavy-ion Collisions显示文摘 | Mo Y J Feng S Q Shi Y F | 2013 | Physical Review C2013，88，88： | 1 |
| 4 | Geochemical investigation of Early Cretaceous igneous rocks along an east-west traverse throughout the central Lhasa Terrane, Tibet显示文摘 | Zhu D C Mo X X Niu Y L Zhao Z D Wang L Q Liu Y S Wu F Y | 2009 | Chem Geol2009，268，34： | 1 |
| 5 | Symptoms of posttraumatic stress disorder,depression,and anxiety among adolescents following the 2008 Wenchuan earthquake in China显示文摘 | Fan F Zhang Y Yang Y Mo L & Liu X | | 0，，01： | 1 |
| 6 | The Lhasa Terrane: Record of a microcontinent and its histories of drift and growth显示文摘 | Zhu D C Zhao Z D Niu Y L Mo X X Chung S-L Hou Z Q Wang L Q Wu F Y | 2011 | Earth Planet Sci Lett2011，301，12： | 1 |
| 7 | Development of microwave assisted extraction for the simultaneous determination of isoflavonoids and sa- ponins in radix astragali by high performance liquid chromatography显示文摘 | SONG J Z MO S F YIP Y K ct al | 2007 | J Sep Sci2007，30，6： | 1 |
| 8 | Efficient Electron Injection from a Bilayer Cathode Consisting of Aluminum and Alcohol-/Water-Soluble Conjugated Polymers显示文摘 | WU H B HUANG F MO Y Q | | 0，，20： | 1 |
| 9 | Effect of anion on micro/ nano-tribological properties of ultra-thin imidazolium ionic liquid films on silicon wafer显示文摘 | Zhao W J Zhu M Mo Y F | 2009 | Colloids Surf A2009，332，： | 1 |
| 10 | Serum immunoreactivity of SMP30 and its tissues expression in hepatocellular carcinoma显示文摘 | Zhou S F Mo F R Bin Y H | 2011 | Clinical Biochemistry2011，44，4： | 1 |
| 11 | Nanotribological proper- ties of precision-controlled regular nanotexture on H-passiva- ted Si surface by current-induced local anodic oxidation 显示文摘 | Mo Y F Zhao W J Huang D M | 2009 | Ultramicroscopy2009，109，： | 1 |
| 12 | VEGF incorporated intocalcium phosphate ceramics promotes vascularisation and boneformation in vivo显示文摘 | Wemike E Montjovent MO f Liu Y ef al | 2010 | Eur Cell Mater2010，19，2： | 1 |
| 13 | Diagnosis technique based on BP and D-S theory 显示文摘 | Mo Q Y Cao J Gao F | 2011 | Advanced Materials Re- search2011，，： | 1 |
| 14 | Circulating CD133 +VEGFR2+ and CD34+ VEGFR2+ cells and arterialfunction in patients with beta - thalassaemia major显示文摘 | CHEUNG Y F SHING C MO Y | 2011 | Ann Hematol2011，8，： | 1 |
| 15 | New species and records of Orbilia (Orbiiiaceae,Ascomycota) from China 显示文摘 | Zhang Y Yu Z F Baral H O Mo M H and Zhang KQ | 2009 | Fungal Diversity2009，36，： | 1 |
| 16 | Fabrication and tribological behavior of patterned multiply-alkylated cyclopentanes ( MACs ) -octadecyhrichlorosilane ( OTS ) dual-component film by a soft lithographic approach显示文摘 | Wang Y Mo Y F Wang L P | 2011 | Tribol Lett2011，41，： | 1 |
| 17 | Precise positioning of lubricant on a surface using the local anodic oxide method 显示文摘 | Mo Y F Wang Y Pu J B | 2009 | Lang- muir2009，25，： | 1 |
| 18 | The repair of the injured adult rat hippocampus with NT-3-chitosan carriers显示文摘 | Mo L H Yang Z Y Zhang A F | | 0，，08： | 1 |
| 19 | Diagnosis technique based on BP and D-S theory 显示文摘 | MO Q Y CAO J GAO F | 2011 | Advanced Materials Research2011，，： | 1 |
| 20 | Notch Signaling and its role in breast cancer显示文摘 | Wu F Stutzman A Mo Y Y | 2007 | Front Biasci2007，12，： | 1 |
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