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| 1 | Clinical outcomes of isolated renal failure compared to other forms of organ failure in patients with severe acute pancreatitis显示文摘AIM To assess differences in clinical outcomes of isolated renal failure(RF) compared to other forms of organ failure(OF) in patients with severe acute pancreatitis(SAP).METHODS Using a prospectively maintained database of patients with acute pancreatitis admitted to a tertiary medical center between 2003 and 2016, those with evidence of persistent OF were classified to renal, respiratory, cardiovascular, or multi-organ(2 or more organs). Data regarding demographics, comorbidities, etiology of acute pancreatitis, and clinical outcomes were prospectively recorded. Differences in clinical outcomes after development of isolated RF in comparison to other forms of OF were determined using independent t and Mann-Whitney U tests for continues variables, and χ~2 test for discrete variables.RESULTS Among 500 patients with acute pancreatitis, 111 patients developed persistent OF: mean age was 54 years, and 75(67.6%) were male. Forty-three patients had isolated OF: 17(15.3%) renal, 25(21.6%) respiratory, and 1(0.9%) patient with cardiovascular failure. No differences in demographics, etiology of acute pancreatitis, systemic inflammatory response syndrome scores, or development of pancreatic necrosis were seen between patients with isolated RF vs isolated respiratory failure. Patients with isolated RF were less likely to require nutritional support(76.5% vs 96%, P = 0.001), ICU admission(58.8% vs 100%, P = 0.001), and had shorter mean ICU stay(2.4 d vs 15.7 d, P < 0.001), compared to isolated respiratory failure. None of the patients with isolated RF or isolated respiratory failure died.CONCLUSION Among patients with SAP per the Revised Atlanta Classification, approximately 15% develop isolated RF. This subgroup seems to have a less protracted clinical course compared to other forms of OF. Isolated RF might be weighed less than isolated respiratory failure in risk predictive modeling of acute pancreatitis. | Amir Gougol Mohannad Dugum Anwar Dudekula Phil Greer Adam Slivka David C Whitcomb Dhiraj Yadav Georgios I Papachristou | 2017 | World Journal of Gastroenterology2017，23，29： | 20 |
| 2 | case of familial hyperlipoproteinemia type Ⅲ hypertriglyceridemia induced acute pancreatitis: role for outpatient apheresis maintenance therapy显示文摘Hypertriglyceridemic pancreatitis(HTGP) accounts for up to 10% of acute pancreatitis presentations in nonpregnant individuals and is the third most common cause of acute pancreatitis after alcohol and gallstones. There are a number of retrospective studies and case reports that have suggested a role for apheresis and insulin infusion in the acute inpatient setting. We report a case of HTGP in a male with hyperlipoproteinemia type Ⅲ who was treated successfully with insulin and apheresis on the initial inpatient presentation followed by bi-monthly outpatient maintenance apheresis sessions for the prevention of recurrent HTGP. We also reviewed the literature for the different inpatient and outpatient management modalities of HTGP. Given that there are no guidelines or randomized clinical trials that evaluate the outpatient management of HTGP, this case report may provide insight into a possible role for outpatient apheresis maintenance therapy. | Mohannad Abou Saleh Emad Mansoor Gregory S Cooper | 2017 | World Journal of Gastroenterology2017，23，40： | 10 |
| 3 | Portal hypertension secondary to myelofibrosis with myeloid metaplasia:A study of 13 cases显示文摘AIM:To describe the clinical presentation and complications of portal hypertension (PH) secondary to myelofibrosis with myeloid metaplasia (MMM).METHODS: Medical records for 123 patients with MMM were reviewed.RESULTS: Thirteen patients with PH secondary to MMM were identified. Median ages at time of MMM and PH diagnosis were 61 and 66 years, respectively. The interval from MMM diagnosis to presentation with one of the PH features ranged from 1 to 11 years. Variceal bleeding and ascites were the most common presentations. Of the eight patients who presented with variceal bleeding, six patients underwent endoscopic variceal ligation (EVL) with no variceal recurrence or hematological worsening during a 12-mo follow up period.CONCLUSION: Patients with MMM might develop PH. Exact mechanisms leading to PH in MMM are still controversial. As in other etiologies, variceal bleeding and ascites are the most common presentations. Anemia may correlate with, and/or predict, the severity of the PH presentation in these patients. EVL can successfully control variceal bleeding in MMM. Further clinical studies are required. | Mohannad Abu-Hilal Jayant Tawaker | 2009 | World Journal of Gastroenterology2009，15，25： | 9 |
| 4 | Use of testicular sperm in couples with SCSA-defined high sperm DNA fragmentation and failed intracytoplasmic sperm injection using ejaculated sperm显示文摘Sperm DNA fragmentation(SDF)has been linked with male infertility,and previous studies suggest that SDF can have negative influence on pregnancy outcomes with assisted reproduction.We performed a retrospective review of consecutive couples with a high SDF level that had intracytoplasmic sperm injection(ICSI)using testicular sperm(T-ICSI).We compared the T-ICSI outcomes to that of two control groups:87 couples with failed first ICSI cycle and who had a second ICSI cycle using ejaculated sperm(Ej-ICSI),and 48 consecutive couples with high sperm chromatin structure assay(SCSA)-defined SDF(>15%)that underwent an ICSI cycle using ejaculated sperm after one or more failed ICSI cycles(Ej-ICSI-high SDF).The mean number of oocytes that were retrieved and the total number of embryos were not different among the three groups.The mean number of transferred embryos in the T-ICSI group was higher than the Ej-ICSI group but not significantly different than the Ej-ICSI-high SDF group(1.4,1.2,and 1.3,respectively,P<0.05).Clinical pregnancy rate in the T-ICSI group was not significantly different than the Ej-ICSI and Ej-ICSI-high SDF groups(48.6%,48.2%,and 38.7%,respectively,P>0.05).No significant difference was found in live birth rate when comparing T-ICSI to Ej-ICSI and Ej-ICSI-high SDF groups.The results suggest that pregnancy outcomes and live birth rates with T-ICSI are not significantly superior to Ej-ICSI in patients with an elevated SCSA-defined sperm DNA fragmentation and prior ICSI failure(s). | Mohannad Alharbi Fadl Hamouche Simon Phillips Jacques Isaac Kadoch Armand Zini | 2020 | Asian Journal of Andrology2020，22，4： | 4 |
| 5 | Low back Pain educaton and short term quality of life:a randomized trial显示文摘 | Jamshidi A Mohannad K | 2007 | BMC Mcusculoskelet Disord2007，28，8： | 1 |
| 6 | Extrathyroidal manifestations of thyroid disease:thyroidophthalmopathy显示文摘 | Hemant Parmar Mohannad Ibrahim | 2008 | Neuroimag Clin N Am2008，18，3： | 1 |
| 7 | Numerical modeling of traffic-induced ground vibration显示文摘 | Mohannad Mhanna Marwan Sadek Isam Shahrour | 2011 | Computers and Geotechnics2011，，： | 1 |
| 8 | Optimization of the polymer concrete used manufacturing bases for precision tool machines显示文摘 | Header Haddad Mohannad A1 Kobaisi | 2012 | Composites Part B2012，43，： | 1 |
| 9 | Targeting multiple signaling pathways by green tea显示文摘 | Naghma Khan Farrukh Afaq Mohannad | 2006 | Cancer Res2006，66，5： | 1 |
| 10 | Targeting multiple signaling pathways by green tea显示文摘 | Naghma Khan Farrukh Afaq Mohannad | 2006 | Cancer Res2006，66，5： | 1 |
| 11 | Extrathyroidal manifestations of thyroid disease:thyroid ophthalmopathy显示文摘 | Hemant Parmar Mohannad Ibrahim | 2008 | Neuroimag Clin N Am2008，18，3： | 1 |
| 12 | The relationship between anatomical variations of the sino-nasal region and chronic sinusitis extension in children显示文摘 | Mohannad Al-Qudah | 2008 | International Journal of Pediatric Otorhinolaryngology2008，，： | 1 |
| 13 | Suggested Mecha- nism for the MAO Ceramic:Coating on Aluminium Sulf- strates Using Bipolar Current Mode in the Alkaline Silicate Electrolytes显示文摘 | MOHANNAD M S BOSTA A MA K J | 2014 | Applied Surface Science2014，308，： | 1 |
| 14 | Successful liver transplantation for acute sickle cell intrahepatic cholestasis: A case report and review of the literature显示文摘BACKGROUND Sickle cell hepatopathy(SCH)is an inclusive term referring to any liver dysfunction among patients with sickle cell disease.Acute sickle cell intrahepatic cholestasis is one of the rarest and most fatal presentations of SCH.We present the 23rd reported case of liver transplantation(LT)for SCH;a rare case of acute sickle cell intrahepatic cholestasis managed with LT from a hepatitis C virus(HCV)nucleic acid amplification test positive donor.CASE SUMMARY A 29-year-old male with a past medical history of sickle cell disease presented with vaso-occlusive pain crisis.On examination,he had jaundice and a soft,nontender abdomen.Initially he was alert and fully oriented;within 24 h he developed new-onset confusion.Laboratory evaluation was notable for hyperbilirubinemia,leukocytosis,anemia,thrombocytopenia,acute kidney injury and elevated international normalized ratio(INR).Imaging by ultrasound and computed tomography scan suggested a cirrhotic liver morphology with no evidence of biliary ductal dilatation.The patient was diagnosed with acute sickle cell intrahepatic cholestasis after excluding competing etiologies of acute liver injury.He underwent LT from an HCV nucleic acid amplification test positive donor 9 d after initial presentation.The liver explant was notable for widespread sinusoidal dilatation with innumerable clusters of sickled red blood cells and cholestasis.On postoperative day 3,HCV RNA was detectable in the patient's peripheral blood and anti-HCV therapy with glecaprevir/pibrentasvir was initiated on postoperative day 23.He subsequently achieved sustained virologic response after completing 3 mo of therapy and has been followed clinically for 12 mo post-transplant.CONCLUSION This case highlights the utility of LT as a viable treatment option for acute sickle cell intrahepatic cholestasis. | Motasem Alkhayyat Mohannad Abou Saleh Mohammad Zmaili Vedha Sanghi Tavankit Singh Carol Rouphael C Roberto Simons-Linares Carlos Romero-Marrero William D Carey Christina C Lindenmeyer | 2020 | World Journal of Hepatology2020，12，3： | 1 |
| 15 | Extrathyroidal manitestations ol thyroid d-sea se:thyroidophthalmopathy显示文摘 | Hemant Parmar Mohannad lbrahim | 2008 | Neuroimag Clin NAm2008，18，3： | 1 |
| 16 | In vitro effect of hes- petidin on root dentin collagen and dere-mineralization 显示文摘 | Sofiqul Md Noriko H Mohannad N | 2012 | Dent- al Mat J2012，31，3： | 1 |
| 17 | Evidence That the Brief Symptom Inventory Can Be Used to Measure Anxiety Quickly and Reliably in Patients Hospitalized for Acute Myocardial Infarction显示文摘 | Mohannad E. Abu Ruz Terry A. Lennie Barbara Riegel Sharon McKinley Lynn V. Doering Debra K. Moser | 2010 | The Journal of Cardiovascular Nursing2010，，2： | 1 |
| 18 | Sister Mary Joseph and Her Nodule: Historical and Clinical Perspective显示文摘 | Mohannad Abu-Hilal James S. Newman | 2009 | The American Journal of the Medical Sciences2009，，4： | 1 |
| 19 | Training Feedforward Networks with the Marquardt Algorithm 显示文摘 | MARTING T HAGAN MOHANNAD B MENHAJ | 1994 | IEEE Trans on Neural Net-Works1994，5，6： | 1 |
| 20 | Natural Stone in Jordan: Characteristics and Specifications and Its Importance in Interior Architecture显示文摘 | Mohannad Tarrad Omar Al-Omari Mohammed AL-Rawashdeh | 2012 | Journal of Environmental Science and Engineering(B)2012，1，6： | 0 |
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