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8篇 您的检索式：作者名="Mojib"

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		题名	作者	年代	出处	被引量
	1	Antimycobacterial activity in vitro of pigments isolated from Antarctic bacteria显示文摘	Mojib N Philpott R Huang J P		0，，：	1
	2	Antimycobacterial activity in vitro of pigments isolated from Antarctic bacteria显示文摘	Mojib N Philpott R Huang JP	2010	Antonie van Leeuwenhoek2010，98，4：	1
	3	Cyclone life cycle characteristics over the Northern Hemisphere in coupled GCMs显示文摘	Ulrike L?ptien Olga Zolina Sergey Gulev Mojib Latif Vladimir Soloviov	2008	Climate Dynamics2008，，5：	1
	4	Detection, expression and quantitation of the biodegradative genes in Antarctic microorganisms using PCR显示文摘	Panicker G Mojib N Aislabie J	2010	Antonie Van Leeuwenhoek2010，97，3：	1
	5	30/3显示文摘	PANICKER G MOJIB N NAKATSUJI T et ah Occurrence and distribution of capB in Antarctic microorganisms and study of its structure and regulation in the Antarctic biodegradative Pseudomonas sp	2010	Extremophiles2010，14，2：	1
	6	Detection, expression and quantitation of the biodegradative genes in Antarctic microorganisms using PCR 显示文摘	Panicker G Mojib N Aislabie J Bej AK	2010	Anton Leeuwenhoek J Microbiol2010，97，3：	1
	7	Detection, expression and quantitation of the biodegradative genes in Antarctic microorganisms using PCR显示文摘	Panicker 0 Mojib N Aislabie J	2009	Antonie van Leeuwenhoek2009，97，：	1
	8	Antimicrobial activity of PVP from an Antarctic bacterium, Janthinobacterium sp. Ant5-2, on multi-drug and methicillin resistant Staphylococcus aureus显示文摘Multiple drug resistant(MDR)and methicillin-resistant Staphylococcus aureus(MRSA)have become increasingly prevalent as a community acquired infection.As a result limited treatment options are available with conventional synthetic antibiotics.Bioprospecting natural products with potent antimicrobial activity show promise for developing new drugs against this pathogen.In this study,we have investigated the antimicrobial activity of a purple violet pigment(PVP)from an Antarctic bacterium,Janthinobacterium sp.Ant5-2 on 15 clinical MDR and MRSA strains.The colorimetric resazurin assay was employed to determine the minimum inhibitory concentration(MIC90)of PVP against MDR and MRSA.The MIC90 ranged between 1.57μg/mL and 3.13μg/mL,which are significantly lower than many antimicrobials tested from natural sources against this pathogen.The spectrophotometrically determined growth analysis and total microscopic counts using Live/dead®BacLight™fluorescent stain exhibited a steady decrease in viability of both MDR and MRSA cultures following treatment with PVP at the MIC levels.In silico predictive molecular docking study revealed that PVP could be a DNA-targeting minor groove binding antimicrobial compound.The continued development of novel antimicrobials derived from natural sources with the combination of a suite of conventional antibiotics could stem the rising pandemic of MDR and MRSA along with other deadly microbial pathogens.	Jonathan P.HUANG Nazia MOJIB Rakesh R.GOLI Samantha WATKINS Ken B.WAITES Rasik RAVINDRA Dale T.ANDERSEN Asim K.BEJ	2012	Natural Products and Bioprospecting2012，2，3：	0

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