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12篇 您的检索式：作者名="Mora MI"

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		题名	作者	年代	出处	被引量
	1	Identification of replication-competent HSV-1 Cga1+ strain signaling targets in human hepatoma cells by functional organeUe proteomics 显示文摘	Santamari a E Mora MI Potel C	2009	Mol Cell Proteomics2009，8，4：	1
	2	High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene显示文摘	Torres-Arzayus MI De Mora JF Yuan J	2004	Cancer Cell2004，6，3：	1
	3	High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene 显示文摘	Torres-Arzayus MI Font de Mora J Yuan J	2004	Cancer Cell2004，6，：	1
	4	The influence of hydrosalpinx on endometrial elafin expression显示文摘	Guedes Neto Ede P Edelweiss MI de Moraes GS	2011	Fertil Steril2011，95，8：	1
	5	Regulation of stathmin phosphorylation in mouse liver progentitor-29 cells during proteasome inhibition显示文摘	Santamaría E Mora MI Mu(n)oz J	2009	Proteomics2009，9，44：	1
	6	Membranous glomerulonephritis in a patient with syphilis显示文摘	Mora Mora MT Gallego Dominguez MS Castellano Cervino MI		0，，：	1
	7	The influence of hydrosalpinx on endometrial elafin expression显示文摘	Guedes Neto Ede P Edelweiss MI de Moraes GS	2011	Fertil Steril2011，95，8：	1
	8	The influence of hydrosalpinx on endom- etrial elafin expression 显示文摘	Guedes Neto Ede P Edelweiss MI de Moraes GS	2011	Fertil Steril2011，95，8：	1
	9	The effect of chronic intraperitoneal infusion of bacterial endotoxin on exocrine pancreas function in rats显示文摘	Vaccaro MI Dagrosa MA Mora MT	1996	Int J Pancreatol1996，19，1：	1
	10	High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene显示文摘	Torres Arzayus MI Font de Mora J Yuan J	2004	Cancer Cell2004，6，3：	1
	11	Strongyloides stercoralis hyperinfection in systemic lupus erythematosus and the antiphospholipid syndrome显示文摘	Mora CS Segami MI Hidalgo JA	2006	Semin Arthritis Rheum2006，36，3：	1
	12	VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway显示文摘Although VEGF-B was discovered as a VEGF-A homolog a long time ago,the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups.Notwithstanding,drugs that inhibit VEGF-B together with other VEGF family members are being used to treat patients with various neovascular diseases.It is therefore critical to have a better understanding of the angiogenic effect of VEGF-B and the underlying mechanisms.Using comprehensive in vitro and in vivo methods and models,we reveal here for the first time an unexpected and surprising function of VEGF-B as an endogenous inhibitor of angiogenesis by inhibiting the FGF2/FGFR1 pathway when the latter is abundantly expressed.Mechanistically,we unveil that VEGF-B binds to FGFR1,induces FGFR1/VEGFR1 complex formation,and suppresses FGF2-induced Erk activation,and inhibits FGF2-driven angiogenesis and tumor growth.Our work uncovers a previously unrecognized novel function of VEGF-B in tethering the FGF2/FGFR1 pathway.Given the anti-angiogenic nature of VEGF-B under conditions of high FGF2/FGFR1 levels,caution is warranted when modulating VEGF-B activity to treat neovascular diseases.	Chunsik Lee Rongyuan Chen Guangli Sun Xialin Liu Xianchai Lin Chang He Liying Xing Lixian Liu Lasse DJensen Anil Kumar Harald FLanger Xiangrong Ren Jianing Zhang Lijuan Huang Xiangke Yin JongKyong Kim Juanhua Zhu Guanqun Huang Jiani Li Weiwei Lu Wei Chen Juanxi Liu Jiaxin Hu Qihang Sun Weisi Lu Lekun Fang Shasha Wang Haiqing Kuang Yihan Zhang Geng Tian Jia Mi Bi-Ang Kang Masashi Narazaki Aaron Prodeus Luc Schoonjans David MOrnitz Jean Gariepy Guy Eelen Mieke Dewerchin Yunlong Yang Jing-Song Ou Antonio Mora Jin Yao Chen Zhao Yizhi Liu Peter Carmeliet Yihai Cao Xuri Li	2023	Signal Transduction and Targeted Therapy2023，8，9：	0

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