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| 1 | Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups显示文摘AIM:To investigate differences in microbes and short chain fatty acid(SCFA) levels in stool samples from Hispanic and non-Hispanic African American,American Indian,and White participants.METHODS:Stool samples from twenty participants were subjected to analysis for relative levels of viable bacteria and for SCFA levels.Additionally,the samples were subjected to 16 S r RNA gene pyrosequencing for identification of bacteria present in the stool.We used a metagenome functional prediction technique to analyze genome copy numbers and estimate the abundance of butyrate kinase in all samples.RESULTS:We found that African Americans had significantly lower levels of acetate,butyrate,and total SCFAs than all other racial/ethnic groups.We also found that participant microbial profiles differed by racial/ethnic group.African Americans had significantly more Firmicutes than Whites,with enriched Ruminococcaceae.The Firmicutes /Bacteroidetes ratio was also significantly higher for African Americans than for Whites(P =0.049).We found Clostridium levels to be significantly and inversely related to total SCFA levels(P =0.019) and we found Bacteroides to be positively associated(P =0.027) and Clostridium to be negatively associated(P =0.012) with levels of butyrate.We also identified a correlation between copy number for a butyrate kinase predicted from 16 S r RNA gene abundance and levels of butyrate in stool.CONCLUSION:The identified differences in gut flora and SCFA levels may relate to colorectal cancer mortality differentials and may be useful as targets for future clinical and behavioral interventions. | Christina M Hester Venkatakrishna R Jala Morgan GI Langille Shahid Umar K Allen Greiner Bodduluri Haribabu | 2015 | World Journal of Gastroenterology2015，21，9： | 2 |
| 2 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 3 | Genetic influences on beef longissimus palatability in Charolais-and Limousin-sired steers and heifers显示文摘 | Wulf D M Tatum J D Green R D Morgan J B Golden B L and Smith G C | 1996 | J Anim Sci1996，74，： | 2 |
| 4 | The commitment-trust theory of relationship marketing 显示文摘 | MORGAN R M HUNT S D | 1994 | Journal of Marketing1994，58，3： | 1 |
| 5 | The Commitment-Trust Theory of Relationship Marketing显示文摘 | HUNT D S | 1994 | Journal of Marketing Research1994，58，： | 1 |
| 6 | Assessment of erosion haz- ard with the USLE and GIS A ease study of the Upper Ewaso Nglro North basin of Kenya显示文摘 | Bancy M Mati Royston P C Morgan Francis N Gichuki John N Quinton Tim R Brewer Hans P l iniger | 2000 | lnternation Journal of Applied Earth Ob- servation and Geoinformation2000，2，2： | 1 |
| 7 | Evaluation of the ergogenic properties of ginseng:an update显示文摘 | Bahrke M S Morgan W R | 2000 | Sports Med2000，29，2： | 1 |
| 8 | Genetic improvement in the yield of winter:afurther evaluation 显示文摘 | AUSTIN R B FORD M A MORGAN C L | 1989 | J Agric Sci1989，112，： | 1 |
| 9 | Radiological manage- ment of hemoptysis: a comprehensive review of diag- nostic imaging and bronchial arterial embolization显示文摘 | Chun J Y Morgan R Belli A M | 2010 | Cardiovasc Intervent Radiol2010，33，： | 1 |
| 10 | The Commitment - Trust Theory of Relationship Marketing 显示文摘 | Morgan R M Hunt S D | 1994 | Journal of Marketing1994，58，3： | 1 |
| 11 | The use of enzymes in pouhry diets显示文摘 | Bedford M R Morgan A J | 1996 | World''s Poultry Science Journal1996，52，： | 1 |
| 12 | Prediction of stress concentrations and degrees of bending in axially loaded tubular K-joints 显示文摘 | Morgan M R Lee M M K | 1998 | Journal of Constructional Steel Research1998，45，1： | 1 |
| 13 | The role of metallic stents in malignant duodenal obstruction 显示文摘 | Scott-Mackie P Morgan R Farrugia M Glynos M Adam A | 1997 | Br J Radiol1997，70，： | 1 |
| 14 | Stereophonic acoustic echo cancellation-an overview of the fundamental problem显示文摘 | M Mohan Sondhi Dennis R Morgan Joseph L Hall | 1995 | IEEE Signal Processing Letters1995，2，8： | 1 |
| 15 | Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue gene 显示文摘 | Parcells M S Anderson A S Morgan R W | 1994 | Virus Genes1994，9，： | 1 |
| 16 | Phase Ⅰ/Ⅱ study of thalidomide in combination with interleukin-2 in patients with matastatic renal cell carcinoma显示文摘 | Amato R J Morgan M Rawat A | 2006 | Cancer2006，106，7： | 1 |
| 17 | Dermatology quality of life scales-ameasure of the impact of skin diseases显示文摘 | Morgan M Mc Creedy R Simpson J | 2007 | British Jour- nal of Dermatology2007，136，2： | 1 |
| 18 | Effects of bone-tar-geted agents on cancer progression and mortality显示文摘 | Coleman R Gnant M Morgan G | 2012 | J Natl Cancer Inst2012，104，： | 1 |
| 19 | Assessment of erosion hazard with the USLE and GIS:a case study of the upper Ewaso Ng'iro North Basin of Kenya显示文摘 | Mati B M Morgan R P C Gichuki F N Quinton J N Brewer T R Liniger H P | | 0，，02： | 1 |
| 20 | Relationship-based competitive advantage: the role of relationship marketing in marketing strategy 显示文摘 | R M Morgan S Hunt | 1999 | Journal of business re search1999，，46： | 1 |
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