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| 1 | Evaluation of microstructure and mechanical properties of squeeze overcast Al7075-Cu composite joints显示文摘Al7075-Cu composite joints were prepared by the squeeze overcast process.The effects of melt temperature,die temperature,and squeeze pressure on hardness and ultimate tensile strength(UTS)of squeeze overcast Al7075-Cu composite joints were studied.The experimental results depict that squeeze pressure is the most significant process parameter affecting the hardness and UTS.The optimal values of UTS(48 MPa)and hardness(76 HRB)are achieved at a melt temperature of 800℃,a die temperature of 250℃,and a squeeze pressure of 90 MPa.Scanning electron microscopy(SEM)shows that fractured surfaces show flatfaced morphology at the optimal experimental condition.Energy-dispersive spectroscopy(EDS)analysis depicts that the atomic weight percentage of Zn decreases with an increase in melt temperature and squeeze pressure.The optimal mechanical properties of the Al7075-Cu overcast joint were achieved at the Al2Cu eutectic phase due to the large number of copper atoms that dispersed into the aluminum melt during the solidification process and the formation of strong intermetallic bonds.Gray relational analysis integrated with the Taguchi method was used to develop an optimal set of control variables for multi-response parametric optimization.Confirmatory tests were performed to validate the effectiveness of the employed technique.The manufacturing of squeeze overcast Al7075-Cu composite joints at optimal process parameters delivers a great indication to acknowledge a new method for foundry practitioners to manufacture materials with superior mechanical properties. | Muhammad Waqas Hanif Ahmad Wasim Muhammad Sajid Salman Hussain Muhammad Jawad Mirza Jahanzaib | 2023 | China Foundry2023，20，1： | 1 |
| 2 | Hoarding behaviour in a person with dementia显示文摘Hoarding is defined as the acquisition and failure to discard a large number of possessions,resulting in significant cluttering and distress to themselves and others.When the severity of hoarding behaviour increases with age,the risk of vulnerability increases,especially in older people with dementia.This pathological comportment tends not to be identified until the patient is hospitalized and needs a home visit for safe discharge planning or when major concerns arise from family or the public.Diagnosing hoarding disorders from secondary conditions with hoarding behaviour can be challenging.A number of assessments and intervention strategies for hoarding can be implemented to improve the health and safety of these patients.A case of a patient with hoarding behaviour in a patient with dementia is described. | Muhammad Hanif Ahmad Shyh Poh Teo | 2022 | Aging Communications2022，4，4： | 0 |
| 3 | SDN Based DDos Mitigating Approach Using Traffic Entropy for IoT Network显示文摘The Internet of Things(IoT)has been widely adopted in various domains including smart cities,healthcare,smart factories,etc.In the last few years,the fitness industry has been reshaped by the introduction of smart fitness solutions for individuals as well as fitness gyms.The IoT fitness devices collect trainee data that is being used for various decision-making.However,it will face numerous security and privacy issues towards its realization.This work focuses on IoT security,especially DoS/DDoS attacks.In this paper,we have proposed a novel blockchain-enabled protocol(BEP)that uses the notion of a self-exposing node(SEN)approach for securing fitness IoT applications.The blockchain and SDN architectures are employed to enhance IoT security by a highly preventive security monitoring,analysis and response system.The proposed approach helps in detecting the DoS/DDoS attacks on the IoT fitness system and then mitigating the attacks.The BEP is used for handling Blockchain-related activities and SEN could be a sensor or actuator node within the fitness IoT system.SEN provides information about the inbound and outbound traffic to the BEP which is used to analyze the DoS/DDoS attacks on the fitness IoT system.The SENcalculates the inbound and outbound traffic features’entropies and transmits them to the Blockchain in the form of transaction blocks.The BEP picks the whole mined blocks’transactions and transfers them to the SDN controller node.The controller node correlates the entropies data of SENs and decides about the DoS or DDoS attack.So,there are two decision points,one is SEN,and another is the controller.To evaluate the performance of our proposed system,several experiments are performed and results concerning the entropy values and attack detection rate are obtained.The proposed approach has outperformed the other two approaches concerning the attack detection rate by an increase of 11%and 18%against Approach 1 and Approach 2 respectively. | Muhammad Ibrahim Muhammad Hanif Shabir Ahmad Faisal Jamil Tayyaba Sehar YunJung Lee DoHyeun Kim | 2022 | Computers, Materials & Continua2022，，3： | 0 |
| 4 | The dilemma of cytomegalovirus and hepatitis B virus interaction显示文摘Hepatitis B virus(HBV)remains a global public health problem despite the availability of effective vaccine and antiviral therapy.Cytomegalovirus(CMV),another hepatotropic virus,is also very prevalent in the general population worldwide.Both HBV and CMV can persist in the host and have potential to reactivate especially with weakened host cellular immunity.Superimposed CMV infection can lead to severe HBV reactivation.The pathogenesis of the co-infection of HBV and CMV remains poorly understood.Studies reported conflicting results regarding the inhibitory effect of CMV on HBV replication.There is an unmet need on the management of co-infection of HBV and CMV;research initiatives dedicated to understanding their interactions are urgently needed. | Muzammil M.Khan Mukarram J.Ali Hira Hanif Muhammad H.Maqsood Imama Ahmad Javier E.G.Alvarez Maria-Andreea Catana Daryl T.Y.Lau | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 5 | Inhibitive efficacy of Nymphoides indica rhizome extract onα-glucosidase, and cross-link formation of advanced glycation end products显示文摘OBJECTIVE: To investigate the inhibitive efficacy of Nymphoides Indica(L.) Kuntze rhizome extract onα-glucosidase and on cross-link formation of advanced glycation end products(AGEs).METHODS: The plant extracts were prepared by cold maceration and fractionated in solvents of diverse polarity. The in vitro α-glucosidase inhibition assay, fluorescence spectrometry and SDS-PAGE analysis was performed for antiglycation assays.RESULTS: During α-glucosidase inhibition assay significant inhibition by chloroform(0.43 mg/mL)and methanol fractions(0.66 mg/mL) was noticed.During the AGEs inhibition assay, both oxidative(BSA-MGO) and non-oxidative(BSA-glucose)modes were employed. The inhibition of AGEs by total extract was considered moderate(IC_(50)0.10 mg/mL) as a result of non-oxidative mode, whereas in case of oxidative mode(BASA-MGO) no activity was recorded. Among fractions the methanolic fraction presented significant results both in oxidative(IC_(50)0.01 mg/mL) and non-oxidative modes(IC_(50) 0.3 mg/mL). Likewise the ethyl acetate fraction was more active in non-oxidative mode(IC_(50)0.04 mg/mL) compared to oxidative mode(IC_(50)0.32 mg/mL).During assay for inhibition of cross-link formation,the chloroform fraction significantly inhibited cross-link formation in a dose dependent mode.CONCLUSION: It was finally concluded that N. Indica rhizome extract possesses significant properties that inhibit α-glucosidase, and AGEs cross-link formation. | Muhammad Hanif Muzammil Ahmad Khan Muhammad Ramzan Abdul Rafey Ali Zaman Imran Aziz Ama'null'ah Adnan Amin | 2021 | Journal of Traditional Chinese Medicine2021，41，3： | 0 |
| 6 | National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma显示文摘A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the experts.The Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this meeting.This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these patients.This coordinated effort can minimise delays and give patients a chance for curative treatment and effective palliation.The diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance cholangiopancreato-graphy.Brush cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for diagnosis.However,histopathologic confirmation is not always required before resection.Endoscopic ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for staging.The only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette classification.Selected patients with unresectable hCCA can be considered for liver transplantation.Adjuvant chemotherapy should be offered to patients with a high risk of recurrence.The use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary discussions.Patients with acute cholangitis can be drained with endoscopic or percutaneous biliary drainage.Palliative chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA. | Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed | 2024 | World Journal of Gastroenterology2024，30，9： | 0 |
| 7 | General Classes of Variance Estimators in Simple Random Sampling Using Multi-auxiliary Variables显示文摘 | Zahoor Ahmad Shoaib Ali Muhammad Hanif | 2013 | Journal of Mathematics and System Science2013，3，5： | 0 |
| 8 | A New Class of L-Moments Based Calibration Variance Estimators显示文摘Variance is one of themost important measures of descriptive statistics and commonly used for statistical analysis.The traditional second-order central moment based variance estimation is a widely utilized methodology.However,traditional variance estimator is highly affected in the presence of extreme values.So this paper initially,proposes two classes of calibration estimators based on an adaptation of the estimators recently proposed by Koyuncu and then presents a new class of L-Moments based calibration variance estimators utilizing L-Moments characteristics(L-location,Lscale,L-CV)and auxiliary information.It is demonstrated that the proposed L-Moments based calibration variance estimators are more efficient than adapted ones.Artificial data is considered for assessing the performance of the proposed estimators.We also demonstrated an application related to apple fruit for purposes of the article.Using artificial and real data sets,percentage relative efficiency(PRE)of the proposed class of estimators with respect to adapted ones are calculated.The PRE results indicate to the superiority of the proposed class over adapted ones in the presence of extreme values.In this manner,the proposed class of estimators could be applied over an expansive range of survey sampling whenever auxiliary information is available in the presence of extreme values. | Usman Shahzad Ishfaq Ahmad Ibrahim Mufrah Almanjahie Nadia H.Al Noor Muhammad Hanif | 2021 | Computers, Materials & Continua2021，，3： | 0 |
| 9 | A Periglacial Palaeoenvionment in the Upper Carboniferous-Lower Permian Tobra Formation of the Salt Range,Pakistan显示文摘The Upper Carboniferous—Lower Permian(Upper Pennsylvanian-Asselian) Tobra Formation is exposed in the Salt and Trans Indus ranges of Pakistan.The formation exhibits an alluvial plain(alluvial fan-piedmont alluvial plain) facies association in the Salt Range and Khisor Range.In addition,a stream flow facies association is restricted to the eastern Salt Range.The alluvial plain facies association is comprised of clast-supported massive conglomerate(Gmc),diamictite(Dm)facies,and massive sandstone(Sm) Hthofacies whereas the stream flow-dominated alluvial plain facies association includes fine-grained sandstone and siltstone(Fss),fining upwards pebbly sandstone(Sf),and massive mudstone(Fm) Hthofacies.The lack of glacial signatures(particularly glacial grooves and striatums) in the deposits in the Tobra Formation,which are,in contrast,present in their timeequivalent and palaeogeographically nearby strata of the Arabian peninsula,e.g.the AI Khlata Formation of Oman and Unayzah B member of the Saudi Arabia,suggests a pro-to periglacial,i.e.glaciofluvial depositional setting for the Tobra Formation.The sedimentology of the Tobra Formation attests that the Salt Range,Pakistan,occupied a palaeogeographic position just beyond the maximum glacial extent during Upper Pennsylvanian-Asselian time. | Irfan U.JAN Shahid IQBAL Sarah J.DA VIES Jan A.ZALASIEWICZ Michael H.STEPHENSON Michael WAGREICH Muhammad HANEEF Muhammad HANIF Sajjad AHMAD | 2017 | Acta Geologica Sinica(English Edition)2017，91，3： | 0 |
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