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3篇 您的检索式:作者名="Nazri Mustaffa"
    题名 作者 年代 出处 被引量
1Anti-hepatitis A seroprevalence among chronic viral hepatitis patients in Kelantan,Malaysia显示文摘AIM:To determine the seroprevalence of anti-hepatitis A virus (HAV) antibodies in patients with chronic liver disease (CLD) and to justify the need for hepatitis A vaccination.METHODS:Patients (n=119) were enrolled between July and September 2009.The diagnosis of CLD was based on the presence of viral markers for more than 6 mo.The diagnosis of liver cirrhosis was based on clinical,biochemical and radiological profiles.Patient serum was tested for anti-HAV IgG.RESULTS:The overall anti-HAV seroprevalence was 88.2%.The aetiology of CLD was hepatitis B in 96 patients (80.7%) and hepatitis C in 23 patients (19.3%).Mean age was 44.4 ± 14 years.Patients were grouped according to age as follows:24 (20.2%) patients in the 21-30 years age group,22 (18.5%) in the 31-40 years age group,31 (26.1%) in the 41-50 years age group,23(19.3%) in the 51-60 years age group and 19 (16.0%) patients aged greater than 60 years,with reported seroprevalences of 66.7%,95.5%,93.5%,91.3% and 94.7%,respectively.There was a marked increase of seroprevalence in subjects older than 30 years (P=0.001).CONCLUSION:Our study demonstrated that patients aged greater than 30 years of age were likely to have natural immunity to hepatitis A.Therefore,hepatitis A vaccination may not be routinely required in this age group.Fazlina Ahmad Nor Aizal Che Hamzah Nazri Mustaffa Siew Hua Gan 2011World Journal of Gastroenterology2011,17,36:1
2A Rome III survey of functional dyspepsia among the ethnic Malays in a primary care setting显示文摘Lee Yeong Yeh Wahab Noriza Mustaffa Nazri Daud Norwati Mohd Noor Noorhayati Shaaban Juwita Chua Andrew Seng Boon 2013BMC gastroenterology2013,14,13:1
3Prognostic prospect of soluble programmed cell death ligand-1 in cancer management显示文摘Aggressive tissue biopsy is commonly unavoidable in the management of most suspected tumor cases to conclusively verify the presence of cancerous cells through histological assessment.The extracted tissue is also immunostained for detection of antigens(tissue tumor markers)of potential prognostic or therapeutic importance to assist in treatment decision.Although liquid biopsies can be a powerful tool for monitoring treatment response,they are still excluded from standard cancer diagnostics,and their utility is still being debated in the scientific community.With a myriad of soluble tissue tumor markers now being discovered,liquid biopsies could completely change the current paradigms of cancer management.Recently,soluble programmed cell death ligand-1(sPD-L1),which is found in the peripheral blood,i.e.serum and plasma,has shown potential as a pre-therapeutic predictive marker as well as a prognostic biomarker to monitor treatment efficacy.Thus,this review focuses on the emergence of sPD-L1 and promising technologies for its detection in order to support liquid biopsies for future cancer management.Nur Amira Khairil Anwar Muhammad Najmi Mohd Nazri Ahmad Hafiz Murtadha Elis Rosliza Mohd Adzemi Venugopal Balakrishnan Khairul Mohd Fadzli Mustaffa Tengku Ahmad Damitri Al-Astani Tengku Din Maya Mazuwin Yahya Juhara Haron Noor Fatmawati Mokhtar 2021Acta Biochimica et Biophysica Sinica2021,53,8:1
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