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| 1 | Antihyperglycemic activity,antihyperlipedemic activity,haematological effects and histopathological analysis of Sapindus mukorossi Gaerten fruits in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antihyperglycemic and antihyperlipidemie properties of hydroalcoholic extract of fruits of Sapindus mukorossi Caerlen and its beneficial effect on haeniatological parameters with histopathological analysis in streptpzotocin induced diabetic rats.Methods:Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and standard drug glybenclamide(0.5 mg/kg body weight) were administered to diabetic rats.Effect of extract on hyperglycemia,hyperlipidemia and hematological parameters was studied in diabetic rats.Histopathological changes in diabetic rat pancreas were also observed after extract and glybenclamide treatment.Results:Daily oral administration of Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and glybenclamide for 20 days showed beneficial effects on blood glucose level(P<0.01) and lipid level.The extract has a favorable effect on the histopathological changes of the pancreas in streptozotocin induced diabetes.Conclusions: These findings reveal that the hydroalcoholic extract of Sapindus mukorossi fruits extract possesses antihyperglycemic and antihyperlipidemie properties.In addition.the extract can prevent various complications of diabetes and improve some haeniatological parameters. | Neeraj Verma G Amresh P K Sahu Neelam Mishra Anil P Singh Ch V Rao | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，7： | 14 |
| 2 | Pathogenesis and clinical spectrum of primary sclerosing cholangitis显示文摘Primary sclerosing cholangitis(PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly with ulcerative colitis, and is also part of the clinical spectrum of Ig G4-related diseases. Smallduct PSC, a variant of PSC, also has an association with inflammatory bowel disease. The exact pathogenesis of PSC is not well understood at present, however, is likely a combination of a genetic predisposition with alteration of the molecular structure of the gut. Abnormal serum liver chemistry and presence of certain autoimmune markers are usually the first indicators leading to a diagnosis of PCS, however, these may often be normal in early stages of this disease. The diagnosis is made by cholangiography, which is now considered the gold standard. PSC is a known pre-malignant condition. Such patients have an increased risk of developing cholangiocarcinoma, gallbladder neoplasia, and colon cancer. Many new treatment modalities have emerged in the recent past, including anti-tumor necrosis factor-α and anti-integrins; however, liver transplantation is the only known cure for PSC. Despite past and present research, PSC remains an enigmatic biliary disease with few viable treatment options. | Neelam G Gidwaney Swati Pawa Kiron M Das | 2017 | World Journal of Gastroenterology2017，23，14： | 4 |
| 3 | Effect of salinity and different nitrogen sources on the activity of antioxidant enzymes and indole alkaloid content in Catharan- thus roseus seedlings显示文摘 | NEELAM M AJAY K G | 2005 | Journal of Plant Physiology2005，163，： | 1 |
| 4 | Endometrial injury to overcome recurrent embryo implantation failure: a systematic review and me- ta-analysis显示文摘 | Neelam P Tarek G Luciano GN | 2012 | Reproductive Biomedicine Online2012，25，6： | 1 |
| 5 | Dual band (MWIR/LWIR) infrared hyper-spectral imager显示文摘 | MICHELE H NEELAM G AMOLD G | 2003 | IEEE2003，1103，5： | 1 |
| 6 | Data collection with a dual-band infrared hyper-spectral imager显示文摘 | DALE J SNITH D NEELAM G | 2005 | SPIE2005，5881，： | 1 |
| 7 | Effect of salt stress on proline metabolism in two high yielding genotypes of greengram显示文摘 | Neelam M Ajay K G | 2005 | Plant Science2005，169，2： | 1 |
| 8 | OAS single-nucleotide polymorphisms and haplotypes are association with variations in immune response to rullea vaccine 显示文摘 | Haralambieva H Neelam D Pnna G | 2010 | Hum Immunol2010，71，4： | 1 |
| 9 | The role of natural resource amenities in attracting retirees: Implications for economic growth policy显示文摘 | Neelam C Poudyal Donald G Hodges H Ken Cordell | 2008 | Ecological Economics2008，2008，： | 1 |
| 10 | Effect of salt stress on proline metabolism in two high yielding genotypes of green gram显示文摘 | Neelam M Ajay K G | 2005 | Plant Science2005，169，： | 1 |
| 11 | Effect of salt stress on praline me-tabolism in two high yidlding genotypes of green gram显示文摘 | NEELAM M AJAY K G | 2005 | Plant Science2005，169，： | 1 |
| 12 | Data collection with a dual-band infrared hyper-spectral imager显示文摘 | DALE J SNITH D NEELAM G | 2005 | SPIE2005，5881，： | 1 |
| 13 | Drug resistant urinary i-solates of Pseudomonas aeruginosa and Acinetobacter显示文摘 | Sharma J Neelam G Chander J | | 0，，03： | 1 |
| 14 | Functional 20S proteasomes in mature human red blood cells 显示文摘 | Neelam S Kakhniashvili D G Wilkens S | 2011 | Exp Biol IVied2011，236，5： | 1 |
| 15 | Effect of salt stress on praline metabolism in two high yidlding genotypes of green gram 显示文摘 | Neelam M Ajay K G | 2005 | Plant Sci2005，169，： | 1 |
| 16 | Effect of salt stress on proline metabolism in two high yielding genotypes of greengram显示文摘 | Neelam M Ajay K G | 2005 | Plant Science2005，169，2： | 1 |
| 17 | Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron - overload murine model显示文摘 | Gavin Y Maria G Neelam K | 2004 | Circulation2004，109，： | 1 |
| 18 | Effect of salt stress on proline metabolism in two high yielding genotypes of greengram显示文摘 | Neelam M Ajay K G | 2005 | Plant Science2005，169，2： | 1 |
| 19 | Endometrial injury to overcome recurrent embryo implantation failure :a systematic review and meta-anaysis显示文摘 | Neelam Potdar Tarek Gelbaya Luciano G Nado | 2012 | Reproductive Biomedicine online2012，25，： | 1 |
| 20 | Drug resistant urinary isolates of Pseudomonas aeruginosa and Acinetobacter species显示文摘 | Sharma J Neelam G Chander J | 2010 | J Glob Infect Dis2010，2，3： | 1 |
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