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| 1 | Diurnal changes in retinal nerve fiber layer thickness with obstructive sleep apnea/hypopnea syndrome显示文摘AIM:To compare the retinal nerve fiber layer(RNFL)thickness in the morning and evening in Thai patients with varying degrees of obstructive sleep apnea/hypopnea syndrome(OSAHS).METHODS:In this cross-sectional study,potential OSAHS patients at Siriraj Hospital underwent polysomnography to determine the severity of OSAHS and an eye examination(including best corrected visual acuity,slit-lamp examination,and Goldmann applanation tonometry).RNFL thickness was recorded once in the morning and once in the evening,using spectral domain optical coherence tomography.Thickness was expressed as an average and given for each quadrant.Patients with ocular or systemic diseases that might affect RNFL thickness were excluded.RESULTS:Forty-one eyes of 41 patients were classified into 4 OSAHS groups.The average and mean RNFL thickness in most of the four quadrants of the severe OSAHS group trended toward being less than those in the comparable quadrants of the other groups in both the morning and evening.In the moderate OSAHS group,the average RNFL thickness and temporal and superior quadrant thickness in the morning were significantly higher than in the evening(P=0.01,P=0.01,and P=0.03,respectively).In the severe OSAHS group,the inferior quadrant thickness in the morning was significantly higher than in the evening(P=0.03).CONCLUSION:The RNFL thickness in the morning was higher than in the evening in moderate OSAHS. | Niphon Chirapapaisan Techawit Likitgorn Mintra Pleumchitchom Darin Sakiyalak Wish Banhiran Manatsawin Saiman Wanicha Chuenkongkaew | 2016 | International Journal of Ophthalmology(English edition)2016，9，7： | 7 |
| 2 | Streamline upwind finite element method for conjugate heat transfer problems显示文摘This paper presents a combined finite element method for solving conjugate heat transfer problems where heat conduction in a solid is coupled with heat convection in viscous fluid flow. The streamline upwind finite element method is used for the analysis of thermal viscous flow in the fluid region, whereas the analysis of heat conduction in solid region is performed by the Galerkin method. The method uses the three-node triangular element with equal-order interpolation functions for all the variables of the velocity components,the pressure and the temperature. The main advantage of the proposed method is to consistently couple heat transfer along the fluid-solid interface. Three test cases, i.e. conjugate Couette flow problem in parallel plate channel, counter-flow in heat exchanger, and conjugate natural convection in a square cavity with a conducting wall, are selected to evaluate the efficiency of the present method. | Niphon Wansophark Atipong Malatip Pramote Dechaumphai | 2005 | Acta Mechanica Sinica2005，21，5： | 3 |
| 3 | Optical coherence tomography in central nervous system demyelinating diseases related optic neuritis显示文摘AIM:To compare the thickness of the peripapillary retinal nerve fiber layer(RNFL)and ganglion cell-inner plexiform layer(GCIPL)among patients with various forms of optic neuritis(ON)and to identify whether any particular parameters or their thinning pattern can be used to distinguish the type of ON.METHODS:This prospective study was conducted at the Department of Ophthalmology,Faculty of Medicine,Siriraj Hospital,Thailand,between January,2015 and December,2016.We enlisted patients over 18 years of age with history of ON and categorized patients into 4 groups:1)aquaporin 4 antibodies(AQP4-IgG)positive;2)multiple sclerosis(MS);3)myelin oligodendrocyte glycoprotein antibodies(MOG-IgG)positive;4)idiopathic-ON patients.Healthy controls were also included during the same study period.All patients underwent complete ophthalmological examination and spectral domain optical coherence tomography(OCT)imaging to analyze RNFL and GCIPL thickness after at least 3mo since the last episode of acute ON.The generalized estimating equation(GEE)models were used to compare the data amongst ON groups. RESULTS: Among 87 previous ON eyes from 57 patients(43 AQP4-IgG+ON,17 MS-ON,8 MOG-IgG+ON,and 19idiopathic-ON),mean logMAR visual acuity of AQP4-IgG+ON,MS-ON,MOG-IgG+ON,and idiopathic-ON groups was 0.76±0.88,0.12±0.25,0.39±0.31,and 0.75±1.08,respectively.Average,superior,and inferior RNFL were significantly reduced in AQP4-IgG+ON,MOG-IgG+ON and idiopathic-ON eyes,relative to those of MS-ON.Differences were not statistically significant for RNFL or GCIPL between the AQP4-IgG+ON and MOG-IgG+ON groups,whereas visual acuity in MOG-IgG+ON was slightly,but not significantly,better(0.39 vs 0.76).Although RNFL thickness in MOG-IgG+ON was significantly reduced as compared to MS-ON,mean visual acuity and GCIPL were not different.CONCLUSION:Thinning of superior and inferior quadrants of RNFL are more commonly seen in MOG-IgG+ON and AQP4-IgG+ON.Long term visual acuity in MOG-IgG+ON is often better than AQP4-IgG+ON,whereas the structural change from OCT is comparable. | Nattapong Mekhasingharak Poramaet Laowanapiban Sasitorn Siritho Chanjira Satukijchai Naraporn Prayoonwiwat Jiraporn Jitprapaikulsan Niphon Chirapapaisan | 2018 | International Journal of Ophthalmology(English edition)2018，11，10： | 3 |
| 4 | Effect of chemical treatments on ‘ Candidatus Liberibacter asiaticus’ infected pomelo ( Citrus maxima )显示文摘 | Thamrongjet Puttamuk Shouan Zhang Yongping Duan Arom Jantasorn Niphone Thaveechai | 2014 | Crop Protection2014，，： | 1 |
| 5 | Streamline upwind finite element method using 6-node triangular element with adaptive remeshing technique for convective-diffusion problems显示文摘A streamline upwind finite element method using 6-node triangular element is presented. The method is applied to the convection term of the governing transport equation directly along local streamlines. Several convective-diffusion examples are used to evaluate effciency of the method. Results show that the method is monotonic and does not produce any oscillation. In addition, an adaptive meshing technique is combined with the method to further increase accuracy of the solution, and at the same time, to minimize computational time and computer memory requirement. | Niphon Wansophark Pramote Dechaumphai | 2008 | Applied Mathematics and Mechanics(English Edition)2008，29，11： | 1 |
| 6 | Clinical expression and mitochondrial deoxyribonucleic acid study in twins with 14484 Leber’s hereditary optic neuropathy:A case report显示文摘BACKGROUND This study aimed to explore clinical and molecular factors that cause discordance for clinical expression of Leber’s hereditary optic neuropathy(LHON)in a pair of identical twins with the 14484 point mutation.CASE SUMMARY Twin patients with the 14484 point mutation were studied for zygosity by using the Short Tandem Repeats Typing system.For the monozygotic twins,the radioactive restriction and densitometric analyses were used to quantitate the heteroplasmy level for the 14484 point mutation.The mitochondrial genome was analyzed to determine influential factors by mitochondrial deoxyribonucleic acid(DNA)sequencing,denaturing high-performance liquid chromatography and next generation sequencing.For the dizygotic twins,the nuclear DNA was analyzed.The twins with 14484 LHON were monozygotic with homoplasmy.No difference in the point mutation in mitochondrial DNA was found.No modifying genes that potentially influenced the disparity in phenotypic expression of LHON were detected in these twins.CONCLUSION This 11-year follow-up of monozygotic twins showed additional genetic modifications and epigenetic factors are possibly associated with discordance for LHON. | Wanicha Leetiratanai Chuenkongkaew Buakhwan Chinkulkitnivat Patcharee Lertrit Niphon Chirapapaisan Supannee Kaewsutthi Bhoom Suktitipat Chalermchai Mitrpant | 2022 | World Journal of Clinical Cases2022，10，20： | 0 |
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