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| 1 | Success rates for various graft materials in tympanoplasty e A review显示文摘Objectives:The aim of this paper is to review how successful each type of grafts is in tympanoplasty.Methods:Pubmed,Google and the Proquest Central Database at Kırıkkale University were queried using the keywords“graft”,“success”“tympanoplasty”,“success rate”with the search limited to the period 1955 to 2017.Results:Various types of graft materials including temporalis fascia,cartilage,perichondrium,periosteum,vein,fat or skin have been used in the reconstruction of tympanic membrane(TM)perforation.Although temporalis fascia ensures good hearing is restored,there are significant concerns that its dimensional stability characteristics may lead to residual perforation,especially where large TM perforations are involved.The“palisade cartilage”and“cartilage island”techniques have been stated to increase the strength and stability of a tympanic graft,but they may result in a less functional outcome in terms of restoring hearing.Smoking habits,the size and site of a perforation,the expertise level of the operating surgeon,age,gender,the status of the middle ear mucosa and the presence of myringosclerosis or tympanosclerosis are all important in determining how successful a graft is.Conclusion:Although temporal fascia is the most commonly used graft material for tympanoplasty,poor graft stability may cause failure.This failure is due to the inclusion of connective fibrous tissue containing irregular elastic fibers present in the grafted fascia.Cartilage grafts offer better ability to resist infection,pressure,and cope with insufficient vascular supply.This means that cartilage grafts are suitable for use in revision cases. | Ali Bayram Nuray Bayar Muluk Cemal Cingi Sameer Ali Bafaqeeh | 2020 | Journal of Otology2020，15，3： | 4 |
| 2 | Nasobronchial interaction显示文摘Upper and lower airways can be considered as a unifiedmorphofunctional unit. In this paper, nasobronchial interactions are evaluated based on literature.To discuss nasobronchial interactions, literature review from Pub Med since 1982 is evaluated. Data base was including the terms 'nasobronchial interaction, nasal and bronchial'. Asthma and rhinosinusitis may be associated with environmental factors and immunological predisposition. Treatment of rhinosinusitis may decrease asthma exacerbations. It was concluded that 'one airway, one disease'-concept may be accepted when considering naso-bronchial interaction. Asthma treatment should also mean treating the nose as good as treating patients with nasal symptoms. To reach the succesful results it should be associated with evaluation of lung functions. | Cemal Cingi Nuray Bayar Muluk Bengu Cobanoglu Tolgahan ?atli O?uzhan Dikici | 2015 | World Journal of Clinical Cases2015，3，6： | 3 |
| 3 | Endoscopic ear surgery显示文摘Objectives:This article reviews the advantages and disadvantages of endoscopic ear surgery(EES).Method:Pubmed,Google and the Proquest Central Database at Kirikkale University were queried using the keywords'endoscopic ear surgery','ear surgery'and'endoscopy'to identify the literature needed for the review.Results:Endoscopes allow for enhanced surgical visualisation.The distal part of the apparatus is illuminated and contains lenses angled to allow a wider view of the operative area.Transcanal endoscopic techniques have transformed the external ear canal(EAC)into an operative gateway.The benefits EES can offer include wider views,enhanced imaging capabilities and increased magnification,and ways to see otherwise poorly visualisable portions of the middle ear.EES permits surgeons to operate using minimally invasive otological techniques.When compared with microscope-assisted surgery,endoscopic tympanoplasty has been shown to require a shorter operating time in some instances.There are a number of drawbacks to EES,however,which include the fact that it is a single-handed technique,that the light source may produce thermal injury and that visualisation using the endoscope is severely curtailed if bleeding is profuse.Conclusion:EES is a safe and effective technique.The current literature supports the idea that the results achieved by endoscopic methods are usually comparably beneficial to results obtained using conventional microscopic methods. | Ismet Emrah Emre Cemal Cingi Nuray Bayar Muluk Joao Flaavio Nogueira | 2020 | Journal of Otology2020，15，1： | 3 |
| 4 | Comparison of multichannel intraluminal impedance-pH monitoring and reflux scintigraphy in pediatric patients with suspected gastroesophageal reflux显示文摘AIM To evaluate the agreement of multichannel intraluminal impedance-p H monitoring(MII-p HM) and gastroesophageal reflux scintigraphy(GES) for the diagnosis of gastroesophageal reflux disease. METHODS Seventy-five consecutive patients with suspectedgastroesophageal reflux disease(GERD) underwent 24-h combined MII-p HM recording and one hour radionuclide scintigraphy during the course of the MIIpH M study. Catheters with 6 impedance channels and 1 p H sensor were placed transnasally. Impedance and p H data analysis were performed automatically and manually. For impedance monitoring, reflux was defined as a retrograde 50% drop in impedance, starting distally and propagating retrogradely to at least the next two more proximal measuring channels. Reflux index(RI, percentage of the entire record that esophageal p H is < 4.0) greater than 4.2% for p HM and number of refluxes more than 50 for 24 h for MII were accepted as positive test results. At scintigraphy, 240 frames of 15 seconds duration were acquired in the supine position. Gastroesophageal reflux was defined as at least one reflux episode in the esophagus. After scintigraphic evaluation, impedance-pH recordings and scintigraphic images were evaluated together and agreement between tests were evaluated with Cohen's kappa.RESULTS Sufficient data was obtained from 60(80%) patients(34 male, 56.7%) with a mean age of 8.7 ± 3.7 years(range: 2.5-17.3 years; median: 8.5 years). Chronic cough, nausea, regurgitation and vomiting were the most frequent symptoms. The mean time for recording of MII-pH M was 22.8 ± 2.4 h(range: 16-30 h; median: 22.7 h). At least one test was positive in 57(95%) patients. According to diagnostic criteria, GERD was diagnosed in 34(57.7%), 44(73.3%), 47(78.3%) and 51(85%) patients by means of p HM, MII, GES and MII-p HM, respectively. The observed percentage agreements/κ values for GES and p HM, GES and MII, GES and MII-p HM, and MII and p HM are 48.3%/-0.118; 61.7%/-0.042; 73.3%/0.116 and 60%/0.147, respectively. There was no or slight agreement between GES and p HM alone, MII alone or MII-p HM. p H monitoring alone missed 17 patients compared to combined MII-p HM. The addition of MII to pH monitoring increased the diagnosis rate by 50%.CONCLUSION No or slight agreement was found among p H monitoring, MII monitoring, MII-pH monitoring and GES for the diagnosis of gastroesophageal reflux disease. | Nuray Uslu Kizilkan Murat Fani Bozkurt Inci Nur Saltik Temizel Hülya Demir Aysel Yüce Biray Caner Hasan Ozen | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 5 | Midkine secretion protects Hep3B cells from cadmium induced cellular damage显示文摘AIM: To evaluate role of midkine secretion during Cadmium (Cd) exposure in the human hepatocyte cell line Hep3B cells. METHODS: Different dosages of Cd (0.5-1-5-10 μg/mL) were applied to Hep3B cells and their effects to apoptosis, lactate dehydrogenase (LDH) leakage and midkine secretion were evaluated as time dependent manner. Same experiments were repeated with exogenously applied midkine (250-5000 pg/mL) and/or 5 μg/mL Cd.RESULTS: Cd exposure induced prominent apoptosis and LDH leakage beginning from lower dosages at the 48th h. Cd induced midkine secretion with higher dosages (P < 0.001), (control, Cd 0.5-1-5-10 μg/mL respectively: 1123 ± 73, 1157 ± 63, 1242 ± 90, 1886 ± 175, 1712 ± 166 pg/mL). Exogenous 500-5000 pg/mL midkine application during 5 μg/mL Cd toxicity prevented caspase-3 activation (control, Cd toxicity, 250, 500, 1000, 2500, 5000 pg/mL midkine+ Cd toxicity, respectively: 374 ± 64, 1786 ± 156, 1545 ± 179, 1203 ± 113, 974 ± 116, 646 ± 56, 556 ± 63 cfu) LDH leakage and cell death in Hep3B cells (P < 0.001). CONCLUSION: Our results showed that midkine secretion from Hep3B cells during Cd exposure protects liver cells from Cd induced cellular damage. Midkine has anti-apoptotic and cytoprotective role during Cd toxicity. Further studies are needed to explain the mechanism of midkine secretion and cytoprotective role of midkine during Cd exposure. Midkine may be a promising theurapatic agent in different toxic hepatic diseases. | Nuray Yazihan Haluk Ataoglu Ethem Akcil Burcu Yener Bulent Salman Cengiz Aydin | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 6 | Protective effect of Spirulina platensis enriched in phenolic compounds against hepatotoxicity induced by CCl 4显示文摘 | Remziye Aysun Kepek?i Sait Polat Ahmet ?elik Nuray Bayat Saadet Demir?rs Saygideger | 2013 | Food Chemistry2013，，3： | 2 |
| 7 | Impact of combining chlorine dioxide and chlorine on DBP formation in simulated indoor swimming pools显示文摘The main objective of this study was to assess the combined use of chlorine dioxide(ClO_2)and chlorine(Cl_2) on the speciation and kinetics of disinfection by-product(DBP) formation in swimming pools using synthetic pool waters prepared with a body fluid analog(BFA)and/or fresh natural water. At 1:25(mass ratio) of ClO_2 to Cl_2, there was no significant reduction in the formation of trihalomethanes(THMs) and haloacetic acids(HAAs) for both BFA solution and natural water compared to the application of Cl_2 alone. When the mass ratio of ClO_2 to Cl_2increased to 1:1, substantial decreases in both THMs and HAAs were observed in the natural water, while there was almost no change of DBP formations in the BFA solution. Haloacetonitriles and halonitromethanes levels in both water matrices remained similar. In the presence of bromide, the overall DBP formation increased in both BFA solution and natural water. For the DBP formation kinetics, after 72 hr of contact time,very low formation of THMs and HAAs was observed for the use of ClO_2 only. Compared to Cl_2 control, however, applying the 1:1 mixture of ClO_2/Cl_2 reduced THMs by > 60% and HAAs by > 50%. Chlorite was maintained below 1.0 mg/L, while the formation of chlorate significantly increased over the reaction time. Finally, in a bench-scale indoor pool experiment, applying ClO_2 and Cl_2simultaneously produced less THMs compared to Cl_2 control and kept chlorite at < 0.4 mg/L, while HAAs and chlorate accumulated over 4-week operation period. | Daekyun Kim Nuray Ates Sehnaz Sule Kaplan Bekaroglu Meric Selbes Tanju Karanfil | 2017 | Journal of Environmental Sciences2017，29，8： | 2 |
| 8 | Effects of octreotide acetate and amniotic membrane on wound healing in experimental glaucoma surgery显示文摘 | Tamer Demir Burak Turgut Ulku Celiker Ibrahim Ozercan Fatih Ulas Nuray Akyol | 2003 | Documenta Ophthalmologica2003，，2： | 2 |
| 9 | Re- moval of disinfection by - product precursors by UF and NF membranes in low - SUVA waters 显示文摘 | Nuray Ates Levent Yilmaz Mehmet Kitis Ulku Yetis | 2009 | Journal of Membrane Science2009，328，12： | 1 |
| 10 | Effect of high pressure (HP) on the quality and shelf life of red mullet (Mullus surmelutus) 显示文摘 | Nuray E Gonca ? Hami A | 2010 | Innovative Food Science and Emerging Technologies2010，11，： | 1 |
| 11 | Effect of high pressure (HP) on the quality and shelf life of red mullet ( Mullus surmelutus )显示文摘 | Nuray Erkan Gonca üretener Hami Alpas | 2010 | Innovative Food Science and Emerging Technologies2010，，2： | 1 |
| 12 | Aydinoglu An incremental response spectrum analysis procedure based on inelastic spectral displacements for multi-Mode seismic performance evaluation 显示文摘 | Nuray M | 2003 | Bulletin of Earthquake Engi- neering2003，1，1： | 1 |
| 13 | Enzymatic synthesis of benzoin in supercritical carbon dioxide显示文摘 | Nuray Celebi a Nuray Yildiz b Ayhan S Demir | 2007 | J Supererit Fluids2007，4，3： | 1 |
| 14 | Surface coal mine area monitoring using multi-temporal high-resolution satellite imagery显示文摘 | Nuray Demirel M. Kemal Emil H. Sebnem Duzgun | 2010 | International Journal of Coal Geology2010，，1： | 1 |
| 15 | Endurance training attenuates exercise-induced oxidative stress in erythrocytes in rats显示文摘 | Nuray O Seyithan T | 2004 | European Journal of Applied Physiology2004，，91： | 1 |
| 16 | The Impact of E-Commerce on International Trade and Employment显示文摘 | Nuray Terzia | 2011 | Procedia Social and Behavioral Sciences2011，，74： | 1 |
| 17 | Effect of different dose gamma radiation and refrigeration on the chemical and sensory properties and microbiological status of aquacultured sea bass ( Dicentrarchus labrax ) 显示文摘 | Ozden O Inugur M Nuray E | 2007 | Radiation Physics and Chemistry2007，76，： | 1 |
| 18 | Dendritic cells from patients with meloma are numerically normal but functionally defective as they fail to upregulate CD80( ( B7 - 1 ) expression by transforming growth factor - batal and interleukin - 10 显示文摘 | Brown R D Pope B Nuray A | 2001 | Blood2001，98，10： | 1 |
| 19 | Kinetics of Nonenzymatic Browning Reaction in Citrus Juice Concentrates during Storage 显示文摘 | Nuray KOCA | 2003 | Turk J Agric2003，，27： | 1 |
| 20 | An incremental response spectrum analysis procedure based on inelastic spectral displacements formulti-mode seismic performance evaluation 显示文摘 | Nuray M A | 2003 | Bulletin of Earthquake Engineering2003，1，1： | 1 |
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