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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | 心房颤动——当今面临的挑战显示文摘在过去数年里,临床和科撞方面对心房颤动(房颤)的关注明显增加,有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常,包括其不良后果和症状,房颤无疑是虽迫切需要有更好治疗方法的一种心律失常。为了达到这一目的,就需要更深刻地认识房颤的机制.以便开发直接影响这一基础病理生理机制的治疗措施。 | Olsson SB Hansson A Hedin E Holm M Ingemansson M Johansson R Meurling C Pehrson S Roijer A Yuan S 方丕华 | 1997 | 中华心律失常学杂志1997，1，1： | 3 |
| 3 | Optical properties of biomimetically produced spectrally selective coatings显示文摘 | Joerger R Klaus-joerger T Olsson E | 2000 | Solar Energy2000，69，16： | 2 |
| 4 | Fundamental pathological lesions in vascular dementia显示文摘 | Brun A Engiuund E | 1996 | Acta Neurol Suppl1996，168，： | 1 |
| 5 | An opti mized grapevine RNA isolation procedure and statisti- cal determination of reference genes for real-time RT- PCR during berry development 显示文摘 | Reid K E Olsson N Sehlosser J | 2006 | BMC plant biology2006，6，1： | 1 |
| 6 | Silver-based crystalline nanoparticles, microbially fabricated 显示文摘 | KLAUS T JOERGER R OLSSON E | 1999 | Proceed- ings of the National Academy of Sciences1999，96，13： | 1 |
| 7 | Heavy trap formation by Athrobotrys oligospora in liquid culture 显示文摘 | FRIMAN E OLSSON S NORDBRING-HERTZ B | 1985 | FEMS Microbiology Ecology1985，31，： | 1 |
| 8 | Adaptive methods for sequential importance sampling with application to state space models 显示文摘 | CORNEBISE J MOULINES E OLSSON J | 2008 | Statistics and Computing2008，18，4： | 1 |
| 9 | High efficiency dye sensitized nanocrystalline solar cells based on sputter deposited Ti oxide films显示文摘 | Gomez M M Lu J Olsson E | 2000 | Solar Energy Materials & Solar Cells2000，64，4： | 1 |
| 10 | Combined Interpretation of Fracture Zones In Crystalline Rock Using Single hole,Crosshole Tomography and Directional Borehole-radar Data显示文摘 | Sandberg E V Olsson O L Falk Lars R | 1991 | The Log Analyst1991，32，： | 1 |
| 11 | Evidence of calcium phosphate depositions in stenotic arteriovenous fistulas显示文摘 | Olsson LF Odselius R Ribbe E | 2001 | Am J Kidney Dis2001，38，2： | 1 |
| 12 | Use of VSC-HVDC for industrial systems having onsite generation with frequency control显示文摘 | Du C Q Agneholm E Olsson G | 2008 | IEEE Transactions on Power Delivery2008，23，4： | 1 |
| 13 | Thoracic aortic aneurysm and dissection:increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987 to 2002显示文摘 | Olsson C Thelin S St(a)hle E | | 0，，： | 1 |
| 14 | Vertical ground reaction force feedback to enhance stroke patients' symmetrical body-weight distribution while rising/sitting down 显示文摘 | Engardt M Ribbe T Olsson E | 1993 | Scand J Rehabil Med1993，25，1： | 1 |
| 15 | Bacteria as workers in the living factory: metal-accumulating bac- teria and their potential for materials science显示文摘 | KLAUS-JOERGER T JOERGER R OLSSON E | 2001 | Trends in Biotechnology2001，19，1： | 1 |
| 16 | Fundamental pathological lesions in vascular dementia显示文摘 | Olsson Y Brun A Engiuund E | 1996 | Acta Neurol Scand Suppl1996，168，： | 1 |
| 17 | Thoracic aortic aneurysm and dissectionincreasing prevalence and improved outcomes reported in a nationwide populationbased study of more than 14 000 cases from 1987 to 2002显示文摘 | Olsson C Thelin S Sthie E | 2006 | Circulation2006，114，12： | 1 |
| 18 | Does an active sun exposure habit lower the risk of venous thrombotic events? AD-lightful hypothesis 显示文摘 | Lindqvist PG Epstein E Olsson H | 2009 | J Thromb Haemost2009，7，4： | 1 |
| 19 | Fault diagnosis in industry using sensor readings and case-based reasoning显示文摘 | OLSSON E FUNK P XIONG N | 2004 | Journal of Intelligent and Fuzzy Systems2004，15，1： | 1 |
| 20 | Increasedgibberellin biosynthesis in transgenic trees promotes growth,biomass production and xylem fiber length 显示文摘 | ERIKSSON M E ISRAELSSON M OLSSON O | 2000 | Nat Biotechnol2000，18，7： | 1 |
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