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| 1 | Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gammasecretase activity显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Nature1999，398，6727： | 1 |
| 2 | Activity-dependent isolation of the presenilin-gamma-secretase complex reveals nicastrin and a gamma substrate显示文摘 | Esler WP Kimberly WT Ostaszewski BL | 2002 | Proc Natl Acad Sci USA2002，99，5： | 1 |
| 3 | 显示文摘 | Esler WP Kimberly WT Ostaszewski BL | 2002 | Proc Natl Acad Sci U S A2002，99，5： | 1 |
| 4 | Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1显示文摘 | Esler WP Kimberly WT Ostaszewski BL | 2000 | Nat Cell Biol2000，2，7： | 1 |
| 5 | Gamma-secretase is a membrane protein complex comprised of presenilin,nicastrin,Aph-1,and Pen-2显示文摘 | Kimberly WT LaVoie MJ Ostaszewski BL | 2003 | Proc Natl Acad Sci USA2003，100，11： | 1 |
| 6 | Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity 显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Nature1999，398，6727： | 1 |
| 7 | Gama-secretease isamembrane protein complex comprised of presenilin,nicastrin,Aph-1,and Pen-2显示文摘 | Kimberly WT LaVoie MJ Ostaszewski BL | 2003 | Proc Natl Acad SCI USA2003，100，： | 1 |
| 8 | Two transmembrane aspartares in presenilin - 1 required for presenilin endoproteolysis and gamma - secretase aetivity显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Nature1999，398，： | 1 |
| 9 | Dopamine Covalently Modifies and Functionally Inactivates Parkin显示文摘 | OSTASZEWSKI BL WEIHOFEN A | 2005 | Nat Med(S1078-8956)2005，11，11： | 1 |
| 10 | Two transmembran aspartates in Presenilin-1 requried for presenilin endoproteolysis and gamma-secretase activity显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Nature1999，39，8： | 1 |
| 11 | ,-secretase is a membrane protein complex com- prised of presenilin, nicastrin, Aph-1, and Pen-2 显示文摘 | Kimberly WT LaVoie M J Ostaszewski BL | 2003 | Proc Natl Acad Sci USA2003，100，11： | 1 |
| 12 | γ-Secretase is a membrane protein complex comprised of presenilin,nicastrin,aph-1,and pen-2显示文摘 | Kimberly WT LaVoie MJ Ostaszewski BL | 2003 | Proc Natl Acad Sci USA2003，100，11： | 1 |
| 13 | Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation显示文摘 | Hong S Quintero-Monzon O Ostaszewski BL | | 0，，： | 1 |
| 14 | Trans - ition - state analogue inhibitors ofγ- secretase binds directly to pressenilin - 1显示文摘 | Esler WP Kimberly WT Ostaszewski BL | 2002 | Nat Cell Biol2002，2，3： | 1 |
| 15 | Soluble Aβoligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes显示文摘 | Hong S Ostaszewski BL Yang T | 2014 | Neuron2014，82，2： | 1 |
| 16 | Soluble Aboligomers are rapidly sequestered from brain ISF in vivo andbind GM1 ganglioside on cellular membranes 显示文摘 | Hong S Ostaszewski BL Yang T | 2014 | Neuron2014，82，2： | 1 |
| 17 | Aggregation of secreted amyloid b-protein into SDS-stable oligomers in cellculture显示文摘 | Podlisny MB Ostaszewski BL Squazzo SL | 1995 | J Biol Chem1995，270，： | 1 |
| 18 | Two transmembrane aspartates in presenilin-one required for presenilin endoproteolysis and gamma-secretase activity显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Nature1999，398，6727： | 1 |
| 19 | Pinkl forms a multiprotein complex with Miro and Milton, linking Pinkl function to mitochondrial trafficking显示文摘 | Weihofen A Thomas KJ Ostaszewski BL | 2009 | Biochemistry2009，48，： | 1 |
| 20 | Two trans- membrane aspartates in presenilin-1 required for preseni- lin endoproteolysis and gamma-secretase activity显示文摘 | Wolfe MS Xia W Ostaszewski BL | 1999 | Na- ture1999，398，6727： | 1 |
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