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| 1 | Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics显示文摘AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single center.METHODS:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related complications.RESULTS:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs.The mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 mm.Fifty-one per cent of SSAs were located in the cecum or ascending colon.Approximately half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous polyps.Synchronous adenocarcinoma was present in seven(4%) cases.Ninety-seven percent of polyps were removed by colonoscopy.CONCLUSION:Among patients with colon polyps,2.9% were found to have SSAs.Most of the SSAs were located in the right side and were safely managed by colonoscopy. | Suryakanth R Gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das | 2010 | World Journal of Gastroenterology2010,16,27: | 7 |
| 2 | Effect of feeding flax and two types of antioxidants on egg pro- duction, egg quality, and lipid composition of eggs 显示文摘 | HAYAT Z CHERIAN G PASHA T N | 2009 | The Journal of Applied Poultry Research2009,18,3: | 1 |
| 3 | Some properties of Renyi entropy and Renyi entropy rate显示文摘 | Golshani L Pasha E Yari G | | 0,,14: | 1 |
| 4 | WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary and endometrium 显示文摘 | Aes G Pasha T Zhang PJ | 2004 | Int J Gynecol Pathol2004,23,2: | 1 |
| 5 | WT1 is differentially expressed in serous, endometrioid, clear cell, and mueinous carcinomas of the peritoneum, fallopian tube, ovary and endometrium 显示文摘 | Acs G pasha T Zhang PJ | 2004 | Int J Gyneeol Pathol2004,23,2: | 1 |
| 6 | Precinditioning enhances cell survival and differentiation of stem cells during transplantation in infracted myocardium显示文摘 | Pasha Z Wang Y G Sheikh R | | 0,,: | 1 |
| 7 | Immunoprofile of endocervical and endometrial stromal cells and its potential application in localization of tumor involvement 显示文摘 | Barroeta JE Pasha TL Acs G | 2007 | Int J Gynecol Pathol2007,26,1: | 1 |
| 8 | Serological profiling of Crohn’s disease and ulcerative colitis patients reveals anti-microbial antibody signatures显示文摘BACKGROUND The healthcare burden of inflammatory bowel disease(IBD)is rising globally and there are limited non-invasive biomarkers for accurate and early diagnosis.AIM To understand the important role that intestinal microbiota play in IBD pathogenesis and identify anti-microbial antibody signatures that benefit clinical management of IBD patients.METHODS We performed serological profiling of 100 Crohn’s disease(CD)patients,100 ulcerative colitis(UC)patients and 100 healthy controls against 1173 bacterial and 397 viral proteins from 50 bacteria and 33 viruses on protein microarrays.The study subjects were randomly divided into discovery(n=150)and validation(n=150)sets.Statistical analysis was performed using R packages.RESULTS Anti-bacterial antibody responses showed greater differential prevalence among the three subject groups than anti-viral antibody responses.We identified novel antibodies against the antigens of Bacteroidetes vulgatus(BVU_0562)and Streptococcus pneumoniae(SP_1992)showing higher prevalence in CD patients relative to healthy controls.We also identified antibodies against the antigen of Streptococcus pyogenes(SPy_2009)showing higher prevalence in healthy controls relative to UC patients.Using these novel antibodies,we built biomarker panels with area under the curve(AUC)of 0.81,0.87,and 0.82 distinguishing CD vs control,UC vs control,and CD vs UC,respectively.Subgroup analysis revealed that penetrating CD behavior,colonic CD location,CD patients with a history of surgery,and extensive UC exhibited highest antibody prevalence among all patients.We demonstrated that autoantibodies and anti-microbial antibodies in CD patients had minimal correlation.CONCLUSION We have identified antibody signatures for CD and UC using a comprehensive analysis of antimicrobial antibody response in IBD.These antibodies and the source microorganisms of their target antigens improve our understanding of the role of specific microorganisms in IBD pathogenesis and,after future validation,should aid early and accurate diagnosis of IBD. | Mahasish Shome Lusheng Song Stacy Williams Yunro Chung Vel Murugan Jin G Park William Faubion Shabana F Pasha Jonathan A Leighton Joshua LaBaer Ji Qiu | 2022 | World Journal of Gastroenterology2022,28,30: | 1 |
| 9 | Single-wall Nanotubes Produced by Metal-catalyzed Disproportionation of Carbon Monoxide显示文摘 | Dai H J Rinzler A G Pasha N | 1996 | Chemical Physics Letters1996,260,: | 1 |
| 10 | Marine metabolites : the sterols of soft coral显示文摘 | SARMA N S KRISHNA M S PASHA S G | 2009 | Chem Rev2009,109,6: | 1 |
| 11 | Cytotoxicity and genotoxicity induced by the pesticide profenofos on cultured human peripheral blood lymphocytes显示文摘 | Pasha Shaik A Jamil K | 2006 | Drug Chem Toxicol2006,29,3: | 1 |
| 12 | 显示文摘 | Dai H J Rinzler A G Pasha N | 1996 | Chem Phys Lett1996,260,: | 1 |
| 13 | Effect of feeding flax and two types of antioxidants on egg production, egg quality, and lipid composition of eggs显示文摘 | Hayat Z Cherian G Pasha T N | 2009 | The Journal of Applied Poul- try Research2009,18,3: | 1 |
| 14 | The structure of anxiety symptoms among adolescents in Iran: A confirmatory actor analytic study of the Spence Children' s Anxiety Scale 显示文摘 | ESSAU CA OLAYA B PASHA G | 2012 | J Anx Disord2012,26,8: | 1 |
| 15 | Single-wall nanotubes produced by metal-catalyzed disproportionation of carbon monoxide 显示文摘 | Dai Hongjie Rinzler Andrew G Nikolaev Pasha | 1996 | Chem PhysLett1996,260,: | 1 |
| 16 | Stapled hemorrhoidopexy compared With conventional hemorrhoidectomy:systematic review of randomized,controlled trials显示文摘 | Pasha J Nisar Austin G Acheson Keith R Neal | 2004 | Dis Colon Rectum2004,47,: | 1 |
| 17 | Theoretical Analysis of Inverse Weibull Distribution 显示文摘 | Khan M S Pasha G R Pasha A H | 2008 | Wseas Trans on Mathematics2008,7,2: | 1 |
| 18 | Dexmedetomidine Reduces the Risk of Delirium, Agitation and Confusion in Critically Ill Patients: A Meta-analysis of Randomized Controlled Trials 显示文摘 | Pasha L Landoni G Nardelli P | 2014 | J Cardiothorac Vasc Anesth2014,,: | 1 |
| 19 | Theoretical Analysis of Inverse Weibull Distribution显示文摘 | Khan M S Pasha G R PASHA A H | | 0,,2: | 1 |
| 20 | WT1 is differentially expressed in serous,endometrioid,clear cell,and mucinous carcinomas of the peritoneum,fallopian tube,ovary,and endometrium显示文摘 | Acs G Pasha T Zhang P J | 2004 | Int J Gynecol Pathol2004,23,2: | 1 |