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您的检索式：作者名="PENG NanBo"
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| 1 | A SVM-kNN method for quasar-star classification显示文摘We integrate k-Nearest Neighbors(kNN) into Support Vector Machine(SVM) and create a new method called SVM-kNN.SVM-kNN strengthens the generalization ability of SVM and apply kNN to correct some forecast errors of SVM and improve the forecast accuracy.In addition,it can give the prediction probability of any quasar candidate through counting the nearest neighbors of that candidate which is produced by kNN.Applying photometric data of stars and quasars with spectral classification from SDSS DR7 and considering limiting magnitude error is less than 0.1,SVM-kNN and SVM reach much higher performance that all the classification metrics of quasar selection are above 97.0%.Apparently,the performance of SVM-kNN has slighter improvement than that of SVM.Therefore SVM-kNN is such a competitive and promising approach that can be used to construct the targeting catalogue of quasar candidates for large sky surveys. | PENG NanBo ZHANG YanXia ZHAO YongHeng | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，6： | 6 |
| 2 | Advances in 3D bioprinting technology for cardiac tissue engineering and regeneration显示文摘Cardiovascular disease is still one of the leading causes of death in the world,and heart transplantation is the current major treatment for end-stage cardiovascular diseases.However,because of the shortage of heart donors,new sources of cardiac regenerative medicine are greatly needed.The prominent development of tissue engineering using bioactive materials has creatively laid a direct promising foundation.Whereas,how to precisely pattern a cardiac structure with complete biological function still requires technological breakthroughs.Recently,the emerging three-dimensional(3D)bioprinting technology for tissue engineering has shown great advantages in generating micro-scale cardiac tissues,which has established its impressive potential as a novel foundation for cardiovascular regeneration.Whether 3D bioprinted hearts can replace traditional heart transplantation as a novel strategy for treating cardiovascular diseases in the future is a frontier issue.In this review article,we emphasize the current knowledge and future perspectives regarding available bioinks,bioprinting strategies and the latest outcome progress in cardiac 3D bioprinting to move this promising medical approach towards potential clinical implementation. | Nanbo Liu Xing Ye Bin Yao Mingyi Zhao Peng Wu Guihuan Liu Donglin Zhuang Haodong Jiang Xiaowei Chen Yinru He Sha Huang Ping Zhu | 2021 | Bioactive Materials2021，6，5： | 4 |
| 3 | Maturation of induced pluripotent stem cell-derived cardiomyocytes and its therapeutic effect on myocardial infarction in mouse显示文摘Induced pluripotent stem cell-derived cardiomyocytes(iPSC-CMs)have an irreplaceable role in the treatment of myocardial infarction(MI),which can be injected into the transplanted area with new cardiomyocytes(Cardiomyocytes,CMs),and improve myocardial function.However,the immaturity of the structure and function of iPSC-CMs is the main bottleneck at present.Since collagen participates in the formation of extracellular matrix(ECM),we synthesized nano colloidal gelatin(Gel)with collagen as the main component,and confirmed that the biomaterial has good biocompatibility and is suitable for cellular in vitro growth.Subsequently,we combined the PI3K/AKT/mTOR pathway inhibitor BEZ-235 with Gel and found that the two combined increased the sarcomere length and action potential amplitude(APA)of iPSC-CMs,and improved the Ca^(2+)processing ability,the maturation of mitochondrial morphological structure and metabolic function.Not only that,Gel can also prolong the retention rate of iPSC-CMs in the myocardium and increase the expression of Cx43 and angiogenesis in the transplanted area of mature iPSC-CMs,which also provides a reliable basis for the subsequent treatment of mature iPSC-CMs. | Peng Wu Xiyalatu Sai Zhetao Li Xing Ye Li Jin Guihuan Liu Ge Li Pingzhen Yang Mingyi Zhao Shuoji Zhu Nanbo Liu Ping Zhu | 2023 | Bioactive Materials2023，，2： | 0 |
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