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| 1 | Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery. | Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen | 2008 | World Journal of Gastroenterology2008，14，45： | 4 |
| 2 | ZrO2-ZrW2O8 composites with tailor-made thermal expansion显示文摘 | Klaartje De Buysser Petra Lommens De Meyer C | 2004 | Ceramics-Silikaty2004，48，4： | 1 |
| 3 | R-AIIyl Nickel( 11 ) complexes with chelating N-Heteroeyclic carbenes:synthesis, structural characterization and catalytic activity显示文摘 | JUNQUERA B L PETRA C M VALERGA P | 2012 | Organometallics2012，31，6： | 1 |
| 4 | ReverseELISA for IgG and IgM antibodies to detect Lassa vi-rus infections in Africa显示文摘 | Petra E Corinna T B Drosten C | 2006 | J Clin Virol2006，37，： | 1 |
| 5 | Spatial and temporal distribution patterns of three trophic levels in a saline lake显示文摘 | PETRA H L SCOTY D C JOHN M M | 1986 | Journal of Plankton Research1986，8，6： | 1 |
| 6 | Salivary cortisol concentrations, stress and quality of life in women with endometriosis and chronic pelvic pain 显示文摘 | PETRELLUZZI K F GARCIA M C PETrA C A | 2008 | Stress2008，11，5： | 1 |
| 7 | Reductive carbonylation of aromatic dinitro compounds with a palladium(phenanthroline)2(triflate)2 catalyst and an aromatic carboxylic acid as catalyst显示文摘 | Petra Wehman Paul C J Kamer | 1996 | J Chem Soc Chem Commun1996，2，： | 1 |
| 8 | Characterization of mtDNA SNP typing and mixture ratio assessment with simultaneous real-time PCR quantification of both allelic states 显示文摘 | Harald N Michael D C Petra G | 2006 | Int J Leg Med2006，120，： | 1 |
| 9 | Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein显示文摘 | Petra N Angelica C Raffaele DF | 1999 | J virol1999，73，12： | 1 |
| 10 | Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis(comet)assay显示文摘 | Clements C Ralph S Petras M | 1997 | Environmental and molecular mutagenesis1997，29，3： | 1 |
| 11 | High-rsolution MR of the intraparotid facial nerve and parotid duct显示文摘 | Theodora D Donald C Petra S | 1997 | AJNR1997，18，： | 1 |
| 12 | The Contribution Soil Organic Matter Fractions to Carbon and Nitrogen Mineralization and Microbial Community Size and Structure 显示文摘 | WILLIAM R C DANIEL A A PETRA M | 2005 | Soil Biology and Biochemistry2005，37，9： | 1 |
| 13 | Accumulation of S-adenosylhomocysteine and S-adenosylmethionine by an ethionine-resistant mutant of bakers'yeast显示文摘 | PETRA C H FRANK F H | 1993 | Process Biochem1993，28，3： | 1 |
| 14 | High resolution MR of the intra-parotid facial nerve and parotid duct 显示文摘 | Theodora D Donald C Petra S | 1997 | AJNR1997，18，： | 1 |
| 15 | On the Biodegradation Performance of an Mg-Y-RE Alloy with Various Surface Conditions in Simulated Body Fluid 显示文摘 | Hanzi A C Gunde Petra Schinhammer M | 2009 | Acta Biomater2009，，5： | 1 |
| 16 | Carotid artery stenting in asymptomatic and surgically high risk patients:Single centre,single,operator results显示文摘 | Veselka J Petra Z Daniela C | 2008 | Int J Angiol2008，17，4： | 1 |
| 17 | Determination of phenolic acids and flavonoids of apple and pear by high-performance liquid chromatography 显示文摘 | Schieber A Petra K Reinhold C | 2001 | Journal of Chromatography A2001，910，： | 1 |
| 18 | Response of microbialactivity and community structure to decreasing soilosmotic and matric potentia显示文摘 | Nasrin C Petra M Richard B | 2011 | Plant Soil2011，344，： | 1 |
| 19 | Stress en- hances airway reactivity and airway inflammation in an animal model of allergic bronchial asthma 显示文摘 | JOACHIM R A QUARCOO D PETRA C | 2003 | Psychosom Med2003，65，5： | 1 |
| 20 | The contribution of soil organic matter fractions to carbon and nitrogen mineralization and microbial community size and structure显示文摘 | William R C Daniel A A Petra M | 2005 | Soil Biology & Biochemistry2005，37，： | 1 |
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