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| 1 | Comparison of 3 techniques for ureteroneocystostomy in cats显示文摘 | Mehl M L Kyles A E Pollard R | 2005 | Vet Surg2005,34,: | 1 |
| 2 | 查看详情显示文摘 | Pollard J A Zhang D S Downing J A Knorr F J McHale J L J | | 0,,: | 1 |
| 3 | Not all arrestins are created equal: Therapeutic implications of the functional diversity of the β-arrestins in the heart显示文摘The two ubiquitous, outside the retina, G protein-coupled receptor(GPCR)adapter proteins, β-arrestin-1 and-2(also known as arrestin-2 and-3,respectively), have three major functions in cells: GPCR desensitization, i.e.,receptor decoupling from G-proteins; GPCR internalization via clathrin-coated pits; and signal transduction independently of or in parallel to G-proteins. Bothβ-arrestins are expressed in the heart and regulate a large number of cardiac GPCRs. The latter constitute the single most commonly targeted receptor class by Food and Drug Administration-approved cardiovascular drugs, with about onethird of all currently used in the clinic medications affecting GPCR function.Since β-arrestin-1 and-2 play important roles in signaling and function of several GPCRs, in particular of adrenergic receptors and angiotensin II type 1 receptors,in cardiac myocytes, they have been a major focus of cardiac biology research in recent years. Perhaps the most significant realization coming out of their studies is that these two GPCR adapter proteins, initially thought of as functionally interchangeable, actually exert diametrically opposite effects in the mammalian myocardium. Specifically, the most abundant of the two β-arrestin-1 exerts overall detrimental effects on the heart, such as negative inotropy and promotion of adverse remodeling post-myocardial infarction(MI). In contrast, β-arrestin-2 is overall beneficial for the myocardium, as it has anti-apoptotic and antiinflammatory effects that result in attenuation of post-MI adverse remodeling,while promoting cardiac contractile function. Thus, design of novel cardiac GPCRligands that preferentially activate β-arrestin-2 over β-arrestin-1 has the potential of generating novel cardiovascular therapeutics for heart failure and other heart diseases. | Anastasios Lymperopoulos Shelby L Wertz Celina M Pollard Victoria L Desimine Jennifer Maning Katie A McCrink | 2019 | World Journal of Cardiology2019,11,2: | 1 |
| 4 | Evaluation of enzyme-linked immunosorbent assay for the determination of polycyclic aromatic hydrocarbons in house dust and residential soil显示文摘 | CHUANG J C POLLARD M A CHOU Y L | 1998 | The Science of the Total Environment1998,224,: | 1 |
| 5 | The calculation of some laminar flows using various discretization schemes 显示文摘 | POLLARD A SIu A L W | 1982 | Computer Methods in Applied Mechanics and Engineering1982,35,3: | 1 |
| 6 | The calculation of some laminar flows using various discretization schemes 显示文摘 | Pollard A Siu A L W | 1982 | Computer Methods in Applied Mechanics and Engineering1982,35,: | 1 |
| 7 | Characterization and application of activated carbon produced from Moringa oleifera seed usks by single-step steam pyrolysis显示文摘 | Warhurst A M Me Connachie G L Pollard S J T | 1997 | Water Res1997,31,: | 1 |
| 8 | Respiratory syncytial virus infections in children and adults显示文摘 | Collins C L Pollard A J | 2002 | J Infect2002,45,1: | 1 |
| 9 | Exploitation of adherent neural stem cells in basic and applied neurobiology 显示文摘 | Pollard S Conti L Smith A | 2006 | Regen Med2006,1,1: | 1 |
| 10 | Carbon-13 nuclear magnetic resonance of 5-substituted uracils显示文摘 | PAUL D E DUNLAP R B POLLARD A L | 1973 | J Am Chem Soc1973,95,: | 1 |
| 11 | Economic benefits at- tributed to opening a preoperative evaluation clinic for out- patients显示文摘 | Pollard J B Zboray A L Mazze R I | 1996 | Anesthesia and Analgesia1996,,83: | 1 |
| 12 | A Review of Recent Artificial Reef Developments in Australia显示文摘 | Branden K L Pollard D A Reimers H A | 1994 | Bulletin of Marine Science1994,55,23: | 1 |
| 13 | A review of recent artificial reef Developments in Australia 显示文摘 | BRAND K L POLLARD D A REMERS H A | 1994 | Bulletin of marine science1994,55,23: | 1 |
| 14 | Investigating the effects of reduced size on the properties of ferroelectrics显示文摘 | Saad M M Baxter P McAneney J Lookman A Sinnamon L J Evans P Schilling A Adams T Zhu X H Pollard R J Bowman R M Gregg J M Jung D J Morrison F D Scott J F | 2006 | IEEE Trans Ultrason Ferroelect Freq Contr l2006,53,: | 1 |
| 15 | Characterisation and applications of activated carbon produced from Moringa oleifera seed husks by single-step steam pyrolysis 显示文摘 | Warhurst A Michael McConnachie Gordon L Pollard Simon J T | 1997 | Water Resource1997,31,4: | 1 |
| 16 | Maerophage biology in devel- opment, homeostasis and disease 显示文摘 | Wynn T A Chawla L Pollard J W | 2013 | Nature2013,496,7446: | 1 |
| 17 | Peripartum myocardial ischemia:a review of Canadian deliveries from 1970 to 1998显示文摘 | Macarthur A Cook L Pollard J K | 2006 | Am J Obstet Gynecol2006,194,: | 1 |
| 18 | The calculation of some laminar flows using various discrimination schemes显示文摘 | Pollard A Siu A L W | 1982 | Comput Math Appl Mech Eng1982,35,: | 1 |
| 19 | A model of carbon evasion and sedimentation in temperate lakes 显示文摘 | Hanson P C Pollard A I Bade D L | 2004 | Global Change Biology2004,10,: | 1 |
| 20 | Multi element analysis of iron ore pellets by laser-induced breakdown spectroscopy and principal components regression显示文摘 | Death D L Cunningham A P Pollard L J | 2008 | Spectrochimica Acta Part B2008,63,7: | 1 |