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| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | 有关正畸初始弓丝就位后的疼痛感——热激活弓丝和超弹弓丝的随机对照研究显示文摘目的:正畸热激活弓丝能够产生比超弹弓丝更轻、更符合生物学的力量.从而能够降低正畸初次就诊所产生的疼痛感。然而.该说法的证据却较少。本研究的目的即比较使用热激活弓丝(HANT)和超弹弓丝(SE)作为正畸初始弓丝就位后患者的疼痛感的差别。方法和材料:共纳入30例患者(男11例,女19例,年龄11~26岁)。上颌或下颌粘接金属托槽.随机使用0.016英寸热激活弓丝和0016英寸超弹弓丝,橡皮圈结扎入槽。要求患者使用视觉模拟量表(VAS)记录7d内不同时刻(8:00.12:00.16:00,2000.2400)的疼痛指数。结果:两组结果均显示疼痛程度最重的为第2天,疼痛程度最轻的为第7天:热激活弓丝组第2.3,4天的VAS评分均显著低于超弹弓丝组(P〈0.005)。针对服用止痛药、体育锻炼、合并其他来源的疼痛和伴随压力性事件等情况做出调整后.结果仍然相同。超弹弓丝组在第3天服用止痛药的频率明显高于热激活组(P〈0.05)。不同时间点间疼痛感未发现明显差异,牙列拥挤与疼痛程度未发现相关性.上下颔的疼痛感也无明显差异。结论:使用热激活弓丝能够降低正畸初诊疼痛感。 | Iacopo Cioffi Antonclla Piccolo Renato Tagliaferri Sergio Paduano Angela Galeotti Roberto Martina 邓金荣 高雪梅 | 2012 | 中国口腔医学继续教育杂志2012，15，6： | 8 |
| 3 | Colorectal cancer prevention in Europe: Burden of disease and status of screening programs显示文摘 | E. Altobelli A. Lattanzi R. Paduano G. Varassi F. di Orio | 2014 | Preventive Medicine2014，，： | 3 |
| 4 | Time efficiency of self-ligating vs conventional brackets in orthodontics: Effect of appliances and ligating systems显示文摘 | Paduano S Cioffi I Iodice G | 2008 | Prog Orthod2008，9，2： | 1 |
| 5 | Pre - stall Behavior of Several High - speed Compressors显示文摘 | Tryfonidis M Etchevers O Paduano J D | 1995 | ASME J of Turbomachinery1995，117，1： | 1 |
| 6 | The Proteomics Big Challenge for Biomarkers and New Drug-Targets Dis- covery 显示文摘 | Savino R Paduano S Preianb M | 2012 | Int J Mol Sci2012，13，13： | 1 |
| 7 | Time efficiency of selfligating vs conventional brackets in orthodontics:Effect of appliances and ligating systems显示文摘 | Paduano S Cioffi I Iodice G | 2008 | Prog Orthod2008，9，2： | 1 |
| 8 | Colorectal cancer screening in Italy: feasibility and cost -effective- ness in a model area 显示文摘 | Sorrentino D Paduano R Bernardis V | 1999 | Eur J Gastroenterol Hepatol1999，11，6： | 1 |
| 9 | Prestall Behaviour of Several High-speed Compressors 显示文摘 | Tryfonidis M Etchvers O Paduano J D | 1995 | ASMEJournal of Turbomachinery1995，117，1： | 1 |
| 10 | Time-Frequency Analysis for Transfer Function Estimation and Application to Flutter Clearance显示文摘 | Feron E Duchesne L Turevskiy A Paduano J D Brenner M | 1998 | Journal of Guidance Control and Dynamics1998，21，3： | 1 |
| 11 | Iuliano R: Pro- tein tyrosine phosphatase PTPRJ is negatively regulated bymicroRNA-328显示文摘 | Paduano F Dattilo V Narciso D | 2013 | Febs J2013，280，2： | 1 |
| 12 | Pre-stall behavior of several high-speed compressors 显示文摘 | Tryfonidis M Etehevers O Paduano J D | 1995 | ASME Jou rnal of Turbomaehinery1995，17，1： | 1 |
| 13 | Active control of rotating stall in a low speed axial compressor显示文摘 | Paduano J D et aI | 1993 | ASME Journal of Turbomachinery1993，115，： | 1 |
| 14 | Silencing of survivin gene bysmall interfering RNAs produces supra-additive growth suppres ?sion in combination with 17-allylamino-17-demethoxygeldana ?mycin in human prostate cancer cells显示文摘 | Paduano F Villa R Pennati M | 2006 | Mol Cancer Ther2006，5，1： | 1 |
| 15 | Prevalence of tooth --size discrepancy among different malocclusion groups显示文摘 | Laino A Quaremba G Paduano S | 2003 | Prog Orthod2003，4，1： | 1 |
| 16 | Prevalence of tooth-size discrepancy among different malocclusion groups显示文摘 | Laino A Quaremba G Paduano S | 2003 | Prog Orthod2003，4，： | 1 |
| 17 | Characterization and fractionation of phenolic compounds extracted from olive mill wastewaters显示文摘 | De Marco E Savarese M Paduano A | 2007 | Food Chemistry2007，104，： | 1 |
| 18 | Pre-stall behavior of several high-speed eompressors显示文摘 | Tryfonidis M Etchevers O Paduano J D | 1995 | Journal of Turbomachinery1995，17，1： | 1 |
| 19 | Rotating stall control in a high-speed stage with inlet distortion: Part 显示文摘 | Spakovszky Z S Weigl H J Paduano J D | 1999 | Journal of Turbomachinery1999，121，3： | 1 |
| 20 | The proteomics big challenge for biomarkers and new drug-targets discovery显示文摘 | Savino R Paduano S PreianòM | 2012 | Int J Mol Sci2012，13，13： | 1 |
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